Peripheral Nerve‐Derived Matrix Hydrogel Promotes Remyelination and Inhibits Synapse Formation

Regeneration of injured nerve tissues requires intricate interplay of complex processes like axon elongation, remyelination, and synaptic formation in a tissue‐specific manner. A decellularized nerve matrix‐gel (DNM‐G) and a decellularized spinal cord matrix‐gel (DSCM‐G) are prepared from porcine sciatic nerves and spinal cord tissue, respectively, to recapitulate the microenvironment cues unique to the native tissue functions. Using an in vitro dorsal root ganglion–Schwann cells coculture model and proteomics analysis, it is confirmed that DNM‐G promotes far stronger remyelination activity and reduces synapse formation of the regenerating axons in contrast to DSCM‐G, Matrigel, and collagen I, consistent with its tissue‐specific function. Bioinformatics analysis indicates that the lack of neurotrophic factors and presence of some axon inhibitory molecules may contribute to moderate axonal elongation activity, while laminin β2, Laminin γ1, collagens, and fibronectin in DNM‐G promote remyelination. These results confirm that DNM‐G is a promising matrix material for peripheral nerve repair. This study provides more insights into tissue‐specific extracellular matrix components correlating to biological functions supporting functional regeneration.     

A Versatile Pt‐Based Core–Shell Nanoplatform as a Nanofactory for Enhanced Tumor Therapy

Hypoxia, one of the representative characteristics in solid tumors, not only reduces the effectiveness of multiple treatments, but also relates to the tumor invasion and metastasis. Here, a hybrid core–shell nanoplatform to produce adequate oxygen, supporting for more effective tumor treatment, is developed. Composed of polydopamine cores, platinum nanoparticle interlayers, and zirconium‐porphyrin (PCN) shells, the hybrid core–shell nanoplatform works like a nanofactory, providing necessary products at different time and space. Platinum nanoparticle interlayers can catalyze the endogenous H₂O₂ to O₂, which plays a dual rule in the enhanced tumor treatment. In the presence of light irradiation, O₂ can be converted into the lethal reactive oxygen species by the PCN shell. In the absence of light irradiation, O₂ ameliorates the hypoxic microenvironment, thereby reduces the invasion and metastasis of the tumor. Through a synergism of enhanced treatment and reduced metastasis, tumors could be treated more vigorously.     

Joint impact of CEE and IQI on NOMA with full-duplex relaying system

Wireless Networks - This paper considers the performance of non-orthogonal multiple-access (NOMA) with full-duplex (FD) relaying system in the presence of two practical undesirable defects, namely...     

再入式集成光学陀螺实验研究

本文在干涉型光纤陀螺 (IFOG)成熟产品模块化结构的基础上 ,提出了无源和有源再入式集成光学陀螺 (IOG)的系统方案。它们在光源、调制器等主要器件上和 IFOG是兼容的。理论分析表明 ,无源和有源 IOG可以分别达到 10 .0°/ h和 0 .1°/ h的精度。     

新型解复用接收器件：理论分析与实验研究

本文对一镜斜置三镜腔光电探测器进行理论分析及实验验证。一镜斜置三镜腔结构是一种新型高性能的光电探测器结构,斜境使滤波波腔与吸收腔之间解耦,因此这种结构的探测器可以同时获得高的量子效率、高的响应效率和窄的光谱响应线宽。本文在理论分析的基础上,利用分立光学器件对斜镜的解耦作用进行了实验验证。     

低功率激光对血液氧合过程的影响研究

为研究低功率激光对血液氧合过程的影响,采用He-Ne激光作为照射光源,从健康人静脉取血,将血液样品分为激光照射和不照射激光的对照组,分别逐次充氧并检测血氧饱和度。结果表明,在一定条件下,激光照射能显著提高血液的氧合速率,使血氧饱和度更快地趋于100％。这一结果提示,用低功率激光照射血液,会加快血液的氧合过程。     

一种新型可溶性PPV的电致发光特性的研究

合成了一种新型聚对苯撑乙稀（PPV）衍生物聚{1,6－已烷二氧代－（2－甲基－1,4－亚苯基）－氰代－[2－甲氧基－5－正幸氧基苯－1,4－二甲基]}－3－甲基－1,4－亚苯基。利用光电子能谱及UV－vis吸收光谱确定了其HOMO和LUMO能级,在此基础上,研制了结构为ITO／Polymer/Al的单层器件,起亮电压4V,电致发光峰值540nm。     

密集型色散管理模式中DM孤子传输特性分析

本文以经典色散管理孤子的传输特性为参照,研究了单信道40Gbit/s密集型色散管理系统内色散管理孤子的诸多传输特性,证实了密集型色散管理模式相对于经典色散管理模式的优势所在,同时给出了系统最佳传输性能与入射功率、分段数、以及脉冲初始宽度等因素的数值关系。     

CVD金刚石薄膜紫外光探测器研究

金刚石薄膜紫外光探测器对紫外光有较高的灵敏度和良好的开关特性。本文讨论了该器件的光电流随入射光波长的变化和开关时间响应。实验证明,金刚石薄膜是一种良好的紫外光探测材料。     

按队长周期性设置EFCI的ABR流量控制算法

本文提出了一种新的基于EFCI的ABR流量控制算法,它的基本思想是扩展EFCI的功能,使其不仅反映网络阻塞状况,而且还反映网络排队状况,在交换机中通过周期性设置EFCI来传递网络的排队信息。仿真结果表明,本文提出的算法比基本EFCI算法具有更好的控制行为,减小了ACR和排队长度的振荡幅度,提高了链路利用率,并具有较高的性能价格比。