辐射制备缓释抗癌药阿糖胞苷的研究

报告了甲基丙烯酸酯类在室温下进行辐射聚合制备缓释抗癌药阿糖胞苷（Ａｒａ－Ｃ）的研究结果。结果表明，不仅亲水性单体，而且疏水性单体（包括ＭＭＡ、ＥＭＡ和ＢＭＡ等）都可用于辐射固化。加入到亲水性基质中的疏水性单体可以延缓药物的离体释放，其顺序是ＭＭＡ＜ＥＭＡ＜ＢＭＡ，央ＭＭＡ－ＨＥＭＡ共聚物中，Ａｒａ－Ｃ释放率随着基质中的ＭＭＡ含量增加而降低。药物的离体释放还受许多困素的控制，结果显示：药物释放量随着     

A truncated poisson regression model with applications to occurrence of adenomatous polyps

Adenomatous polyps are considered as the dominant precursor lesion of colorectal cancer. A phase III colorectal cancer prevention trial, conducted by the Arizona Cancer Center, concerns the ability of wheat bran fibre supplement to reduce the recurrence of adenomatous polyps. All participants in the study are to have had colorectal polyps detected and removed during a baseline (qualifying) colonoscopy within three months prior to enrolment. In this paper, our interest focuses on occurrence of adenomatous polyps at the baseline colonoscopy. We use a truncated Poisson model to fit these types of data. We develop a regression model to assess the effects of explanatory factors on the positive counting variable. We fit truncated Poisson parameters by a log-linear regression model and estimate regression parameters by the maximum likelihood procedure. Finally, we apply it to the baseline colonoscopy data from the Wheat Bran Fiber study.     

STRUCTURE REPRESENTATION OF THE SPECIFIC FRACTIONS FROM PINGSHUO COAL

Basic data of four fractions, PM₁, PM₆, PM₇and PM₈, derived from Pingshuo bituminous coal were obtained by ultimate analyses, mean molecular weight measure, GC/MS, ¹³C-NM R, ¹H-NM R and FTIR technigues. A method of calculating the average molecular parameters of the fractions is introduced. Based on the calculated parameters, the molecular structure models of the fractions of PM₆, PM;and PM₈are constructed. Significant structural information about the saturated hydrocarbon and aromatic hydrocarbon with heteroatom groups is given also.     

Simulation of programmable logic controller

The development and test of a PLC control program takes time, increases equipment down-time, and might damage hardware due to program errors. All of these problems can be eliminated if there is a computer simulation system for testing control programs off line. This paper presented a new method, called Direct Sequential Method, for simulating PLCs. This method resolves a ladder logic sequentially by applying a series of logic deductions. This simulation system has been implemented in C and tested successfully.     

Improved Poisson intensity estimation: denoising application using Poisson data

Recently, Timmermann and Nowak developed algorithms for estimating the means of independent Poisson random variables. The algorithms are based on a multiscale model where certain random variables are assumed to obey a beta-mixture density function. Timmermann and Nowak simplify the density estimation problem by assuming the beta parameters are known and only one mixture parameter is unknown. They use the observed data and the method of moments to estimate the unknown mixture parameter. Taking a different approach, we generate training data from the observed data and compute maximum likelihood estimates of all of the beta-mixture parameters. To assess the improved performance obtained by the proposed modification, we consider a denoising application using Poisson data.     

An investigation of bulk recycling planning for an electronics recycling facility receiving industrial returns versus residential returns

Since most end-of-life electronics equipment contain hazardous materials such as lead solder alloys or lead-impregnated glass, it is important to divert them from landfills. For end-of-life products that are not repairable and do not contain reusable parts, bulk recycling is an alternative to recover base materials. In this paper, we contrast production and recycling planning and distribution decisions, activities, and costs. We reveal that while a traditional production facility connects suppliers and customers, a recycling facility connects both "input" and "output" customers. As a result, decisions in short-term bulk recycling planning include what products to accept, what products to process and reprocess, and what products to carry in inventory. Many recyclers set prices to receive "input" based on experience. For various prices to receive "input", we use a new analytical model to investigate the sensitivity of the short-term bulk recycling planning decisions in products from two different sources: industrial returns versus residential returns. The results of the case study show that different decisions are recommended for the industrial returns versus the residential returns when the total quantity of the incoming products is equal.     

A vectorial boundary element method analysis of integrated optical waveguides

In this paper, a new vectorial boundary element method is introduced and applied to the modal analysis of dielectric waveguides with piecewise homogeneous refractive indexes. The procedure, which is free of spurious modes, determines the full field distribution from the longitudinal fields at the refractive index boundaries. Singular kernels are evaluated through series solutions while the electric field discontinuity at corners is accommodated through either a grid refinement technique or a semianalytic approach. Our formalism generates propagation constants and modal field distributions for several representative refractive index profiles with far higher accuracy than standard finite-difference or finite-element procedures.     

热分析在PVA纤维预处理中的应用

用差热、热重法对原丝的热性能及由不同预处理方法所引起的PVA纤维的热行为变化进行了研究;并通过模拟脱水条件,用不同升温速率,求出了经不同预处理纤维的脱水反应活化能。结果表明,PVA原丝在230℃有一软化点,三种预处理都不同程度地影响了原丝的热效应变化;纤维在180～340℃主要为脱水反应;原丝及经脱水剂、O_3和O_3综合脱水剂处理的纤维,其脱水反应的表观活化能分别为:164.3kJ/mol,92.9kJ/mol,130.5kJ/mol和117.6kJ/mol。     

An observer-based robust adaptive controller for permanent magnet synchronous motor drive with initial rotor angle uncertainty

An observer-based robust adaptive nonlinear position and speed tracking controller is developed for a permanent magnet synchronous motor with initial rotor angle uncertainty. The unknown initial rotor position is treated as a constant motor parameter in the development of the controller. An incremental encoder, which provides relative position variation of the rotor, is used along with stator current signals to achieve stable control. However, the controller does not require the knowledge of motor parameters and it only assumes friction, external disturbances, and model uncertainties are bounded. By using state observers, the measurement of acceleration and load torque, which is required usually in the nonlinear controller design with high tracking performance, is avoided. The stability of the control system and tracking convergence are guaranteed using Lyapunov theory. Finally, the stability and efficacy of the proposed drive system are verified by experimental results.