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181.
Jha Sudan Seo Changho Yang Eunmok Joshi Gyanendra Prasad 《Multimedia Tools and Applications》2021,80(3):3981-3996
Multimedia Tools and Applications - This paper introduces a system capable of real-time video surveillance in low-end edge computing environment by combining object detection tracking algorithm.... 相似文献
182.
Babu R. Dawadi Danda B. Rawat Shashidhar R. Joshi Pietro Manzoni Martina M. Keitsch 《International Journal of Network Management》2021,31(4):e2145
This paper studies a problem for seamless migration of legacy networks of Internet service providers to a software-defined networking (SDN)-based architecture along with the transition to the full adoption of the Internet protocol version 6 (IPv6) connectivity. Migration of currently running legacy IPv4 networks into such new approaches requires either upgrades or replacement of existing networking devices and technologies that are actively operating. The joint migration to SDN and IPv6 network is considered to be vital in terms of migration cost optimization, skilled human resource management, and other critical factors. In this work, we first present the approaches of SDN and IPv6 migration in service providers' networks. Then, we present the common concerns of IPv6 and SDN migration with joint transition strategies so that the cost associated with joint migration is minimized to lower than that of the individual migration. For the incremental adoption of software-defined IPv6 (SoDIP6) network with optimum migration cost, a greedy algorithm is proposed based on optimal path and the customer priority. Simulation and empirical analysis show that a unified transition planning to SoDIP6 network results in lower migration cost. 相似文献
183.
Dr. Anand Kumar Awasthi Dr. Somnath D. Bhagat Aditi Banerjee Prof. Aasheesh Srivastava 《Chembiochem : a European journal of chemical biology》2023,24(20):e202300449
Lipids are key constituents of numerous biomedical drug delivery technologies. Here, we present the design, synthesis and biophysical characterizations of a library of cationic lipids containing an acetal residue in their linker region. These cationic acetal lipids (CALs) were conveniently prepared through a trans-acetalization protocol from commercially available precursors. NMR studies highlighted the conformational rigidity at the acetal residue and the high hydrolytic stability of these CALs. Fluorescence anisotropy studies revealed that the CAL with a pyridinium headgroup (CAL1) formed highly cohesive vesicular aggregates in water. These structural and self-assembly features of the CAL1 allowed up to 196 % w/w loading of curcumin (Cur) as a representative hydrophobic drug. A reconstitutable formulation of Cur was obtained as a result, which could deliver the drug inside mammalian cells with very high efficiency. The hemocompatibility and cytocompatibility of CAL1 was significantly enhanced by creating a coating of polydopamine (PDA) onto its vesicular assemblies to produce hybrid lipid-polymer nanocapsules. This work demonstrates rapid access to the useful synthetic lipid formulations with high potential in drug and gene delivery applications. 相似文献
184.
Aditi Dixit Dr. Jeet Kalia 《Chembiochem : a European journal of chemical biology》2023,24(13):e202200755
Metabolites orchestrate cellular processes as either substrates, co-enzymes, inhibitors, or activators of cellular proteins such as enzymes and receptors. Although traditional biochemical and structural biology-based approaches have been successfully employed for the discovery of protein-metabolite interactions, they often fail to detect transient and low-affinity biomolecular relationships. Another limitation of these approaches is that they are performed under in vitro conditions lacking the physiological context. Recently developed mass spectrometry-based methodologies overcome both these shortcomings, and have resulted in the discovery of global protein-metabolite cellular interaction networks. Herein, we describe traditional and modern approaches for the discovery of protein-metabolite interactions, and discuss the impact of these discoveries on our understanding of cellular physiology and on drug development. 相似文献
185.
Geeta Arora Pinkey Chauhan Muhammad Imran Asjad Varun Joshi Homan Emadifar Fahd Jarad 《计算机系统科学与工程》2023,45(3):2647-2658
The term ‘optimization’ refers to the process of maximizing the beneficial attributes of a mathematical function or system while minimizing the unfavorable ones. The majority of real-world situations can be modelled as an optimization problem. The complex nature of models restricts traditional optimization techniques to obtain a global optimal solution and paves the path for global optimization methods. Particle Swarm Optimization is a potential global optimization technique that has been widely used to address problems in a variety of fields. The idea of this research is to use exponential basis functions and the particle swarm optimization technique to find a numerical solution for the Sine-Gordan equation, whose numerical solutions show the soliton form and has diverse applications. The implemented optimization technique is employed to determine the involved parameter in the basis functions, which was previously approximated as a random number in the work reported till now in the literature. The obtained results are comparable with the results obtained in the literature. The work is presented in the form of figures and tables and is found encouraging. 相似文献
186.
A systematic model is presented for a free expansion polymer foaming process that includes simultaneous nucleation and bubble growth. An influence volume approach, which couples nucleation and bubble growth, is used to account for the limited supply of dissolved gas. The melt rheology is described using the Larson viscoelastic model. The initial conditions are obtained at the upper bound of critical cluster size under conditions of elastic deformation. The resulting set of equations are solved using a combination of numerical techniques. A parametric study is conducted to examine the effects of key process variables on bubble growth, nucleation, and final bubble size distribution. It shows that the factors influencing nucleation and growth affect the ultimate bubble sizes and their distribution. The Gibbs number, a dimensionless measure of the barrier to overcome for nucleation, has the strongest impact on the cellular structure of the foam. © 1998 John Wiley & Sons, Inc. J Appl Polym Sci 67:1353–1368, 1998 相似文献
187.
The genetic cost of sexual reproduction has been attributed to two causes in mathematical formulations: male function or genome dilution. We develop and analyse a genetic model that shows that both costs occur, depending upon the conditions. The model differs from previous formulations in that the level of output and fertilization success of male gametes produced by hermaphrodites that are asexual in their female function (henceforth "parthenogenetic hermaphrodites") are treated as variables, rather than constants fixed at 0 or 1, as has previously been the case. By expressing the cost of sex in terms of per capita egg loss of sexual individuals and parthenogenetic hermaphrodites, we partition the cost into components due to male function and genome dilution. Which component dominates the cost of sex depends upon the relative male gamete output of the parthenogenetic hermaphrodites. The cost of sex is observed to increase, or remain unchanged in some marginal cases, with increases in (i) frequency of parthenogenetic hermaphrodites, (ii) fertilization success of male gametes produced by parthenogenetic hermaphrodites and (iii) potential eggs lost by diverting resources to male gamete production. In certain situations, parthenogenetic hermaphrodites with an intermediate level of male gamete output have the greatest fitness advantage over sexual individuals. If heritable variation for levels of male gamete output exists among parthenogenetic hermaphrodites, this raises the possibility of the evolution of optimal levels of male gamete production by parthenogenetic hermaphrodites through natural selection, in situations of recurring invasion of asexual populations by propagules from sexual populations, a scenario that is increasingly being appreciated as potentially fairly likely to occur in nature. 相似文献
188.
Garimella S.V. Joshi Y.K. Bar-Cohen A. Mahajan R. Toh K.C. Carey V.P. Baelmans M. Lohan J. Sammakia B. Andros F. 《Components and Packaging Technologies, IEEE Transactions on》2002,25(4):569-575
The presentations made, as well as the discussions, in the panels at the workshop, Thermal Challenges in Next Generation Electronic Systems (THERMES), are summarized in this paper. The panels dealt with diverse topics including thermal management roadmaps, microscale cooling systems, numerical modeling from the component to system levels, hardware for future high performance and Internet computing architectures, and transport issues in the manufacturing of electronic packages. The focus of the panels was to identify barriers to further progress in each area that require the attention of the research community. 相似文献
189.
Unmetered electricity supply to agriculture has given rise to a unique and invidious water–energy–food nexus in India. Metering of agricultural consumers has been suggested as a way to break the nexus, but most states have not been able to meter farmers due to their opposition . The only exception is the state of West Bengal. Using primary data from a household survey conducted in 2010 when the metering process was still underway, this paper argues that farmers’ support for metering in West Bengal can be explained in terms of the economics of groundwater use and politics surrounding agriculture and groundwater in the state. 相似文献
190.
S.R. Joshi 《The Science of the total environment》1985,41(3):219-233
The 210Pb and 137Cs profiles are determined at five locations in Georgian Bay and Lake Huron. Compaction-corrected recent sedimentation rates are derived for all locations using the 210Pb data. The rates range from 0.13 ± 0.03 mm y?1 (2.2 ± 0.4 mg cm?2 y?1) to 0.78 ± 0.06 mm y?1 (14.5 ± 1.1 mg cm?2 y?1). Except for one location, the rates show marginal to good agreement with those estimated from palynological measurements at four of the five study locations. 137Cs profiles at study locations suggest that the top portions of the sediment cores were satisfactorily retrieved during coring and sectioning operations. However, considerable downward migration of 13Cs is noted at three locations. The fluxes of excess 210Pb vary between 0.06 and 0.27 pCi cm?2 y?1. The average depositional flux is found to be considerably lower than the flux of atmospheric 210Pb. It is postulated that the deposition of atmospheric 210Pb in Lake Huron and Georgian Bay sediments is limited by the supply of scavenging particulates. 相似文献