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101.
The Multidimensional Impact of Cancer Risk Assessment (MICRA) is a new tool to measure the specific impact of result disclosure after genetic testing. The authors compared its performance with that of questionnaires measuring general and cancer-specific distress. Participants (158 women) responded 1 month after they received genetic test results. The women were divided into 4 standard clinical test result groups: BRCA1/2 positive, BRCA1/2 negative, panel negative, and true negative. Factor analysis supported the formation of 3 subscales: Distress (6 items, α= .86), Uncertainty (9 items, α= .77), and Positive Experiences (4 items, α= .75). All 3 MICRA subscales differentiated participants who were BRCAI/2 positive from the other 3 groups. MICRA thus helps identify subgroups of vulnerable genetic testing participants. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
102.
    
Summary This study showed that the bitterness of dipeptide methyl esters depends on the amino acid sequence and that a N-terminall-phenylalanine residue is more effective than some other amino acid residues with hydrophobic side chains. It was observed that dipeptide benzyl esters were notably more bitter than the corresponding methyl esters and that their bitterness depends on the configuration of the C-terminal amino acid. These results exhibit analogies with those obtained with denatonium chloride derivatives, which suggests that the model of interaction with the bitter receptor previously proposed for denatonium chloride is applicable to dipeptides and their ester derivatives.
Struktur — Aktivitätsbeziehung von bitteren Dipeptidestern
Zusammenfassung Diese Studie zeigt, daß die Schwellenwerte der Bitterkeit von Dipeptidmethylestern von der Aminosäuresequenz abhängt und daß ein N-terminalerl-Phenylalaninrest wirksamer ist als andere Aminosäuren mit hydrophoben Seitenketten. Wir haben beobachtet, daß die Dipeptidbenzylester deutlich bitterer sind als die entsprechenden Methylester und daß die Bitterkeit von der Konfiguration der C-terminalen Aminosäure abhängt. Diese Resultate zeigen Ähnlichkeiten mit denen der Derivate von Denatoniumchlorid, woraus zu schließen ist, daß das für Denatoniumchlorid schon früher vorgeschlagene Modell der Wechselbeziehung mit dem Rezeptor der Bitterkeit auf Dipeptide und ihre Ester anwendbar ist.
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103.
The dependence of thermo-mechanical, and mechanical properties on various rare earth dopants (RE) including Nd2O3, Er2O3, and Yb2O3 in 0.4MgF2-0.4BaF2-0.1Ba(PO3)2-0.1Al(PO3)3 glasses (MBBA system) is systematically investigated. MBBA system doped with RE dopants presented the potential application in the field of communication and high power layer system in the previous reports. In this work, it is found that the density of the doped glass increases with an increasing of RE concentration, which could be understood in terms of cationic field strength (CFS) effect. The Knoop hardness is found to decrease with the loading time and dopant concentration due to the indentation size effect (ISE) effect. The observed decrease of thermal expansion coefficient and the increase of glass transition temperature T g with increasing dopant concentration are elucidated in terms of the increasing number of strong covalent bonds with increasing RE dopant concentration. Those results will be of paramount importance before designing optical devices.  相似文献   
104.
There are at least three heterogeneous catalyst systems of interest for low-pressure polymerization of olefins to high polymers:  相似文献   
105.
Durch Kombination eines Plasmaspektrometers (ICP) mit einer neuen Apparatur zur elektrothermischen Verdampfung konnte der Gehalt an metallischem Calcium in niedrig legiertem, calciumbehandeltem Stahl bestimmt werden. Die kontrollierte Erwärmung von Stahlspänen auf 2 000°C führt zur vollständigen Verdampfung des elementaren Calciums, während das chemisch gebundene Calcium bei dieser Temperatur nicht verdampft. Das verdampfte Calcium wurde mit Argon in das Plasmaspektrometer transportiert, und das erzeugte Emissionsspektrum wurde zur quantitativen Auswertung genutzt.  相似文献   
106.
107.
Teachers of introductory courses in psychology and those who wrote the textbooks for the courses at the start of the 20th century represented the new psychology that replaced the old psychology of mental philosophy. Teachers and texts presented psychology as a natural science of the mind and mental processes, described its methods, and suggested its potential applications to practical concerns. Textbooks and teachers varied in their approaches to psychology, their priorities among its methods, and their emphases on applying psychology. The introductory course in psychology accurately reflected the state of the discipline at the turn of the century. (PsycINFO Database Record (c) 2010 APA, all rights reserved)  相似文献   
108.
We monetize the cost for moving to a culturally different location. We combine administrative social security panel data with a proxy for cultural difference based on historical dialect dissimilarity between German counties. Conditional on geographic distance and pre‐migration wage profiles, we find that migrants demand a (indexed with respect to local rents) wage premium of about 1 (1.5) per cent for overcoming one standard deviation in cultural dissimilarity. The effect is driven by males and those who earn above average occupational wages before migration, and more pronounced for geographically short moves.  相似文献   
109.
The large amount video data produced by multi‐channel, high‐resolution microscopy system drives the need for a new high‐performance domain‐specific video compression technique. We describe a novel compression method for video microscopy data. The method is based on Pearson's correlation and mathematical morphology. The method makes use of the point‐spread function (PSF) in the microscopy video acquisition phase. We compare our method to other lossless compression methods and to lossy JPEG, JPEG2000, and H.264 compression for various kinds of video microscopy data including fluorescence video and brightfield video. We find that for certain data sets, the new method compresses much better than lossless compression with no impact on analysis results. It achieved a best compressed size of 0.77% of the original size, 25× smaller than the best lossless technique (which yields 20% for the same video). The compressed size scales with the video's scientific data content. Further testing showed that existing lossy algorithms greatly impacted data analysis at similar compression sizes. Microsc. Res. Tech. 78:1055–1061, 2015. © 2015 Wiley Periodicals, Inc.  相似文献   
110.
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