OBJECTIVE: To evaluate the effect of maternal age on outcomes for IVF and GIFT in women 40 to 45 years of age. DESIGN: Retrospective. SETTING: Boston IVF, a free-standing university-affiliated IVF and GIFT unit. PATIENTS: A total of 2,931 cycles of IVF and 1,826 cycles of GIFT were analyzed in women undergoing assisted reproductive technologies (IVF or GIFT) using autologous eggs. INTERVENTIONS: Medical records of patient outcomes were reviewed. RESULTS: For patients undergoing IVF, the cancellation rate for initiated cycles showed significant differences in women aged 25 to 39 (38.3%), women aged 40 to 43 (49.5%), and women aged 44 to 45 years (69.5%). A significantly lower delivery rate per stimulation and delivery rate per retrieval was found in women aged 40 to 43 years when compared with women aged 25 to 39 years. No deliveries occurred in 59 cycles in women aged 44 to 45 years, thereby representing a significant difference when compared with both women aged 25 to 39 years and women aged 40 to 43 years. For patients undergoing GIFT, the cancellation rate for initiated cycles was significantly higher in women aged 40 to 43 (25.0%) and 44 to 45 years (31.0%) when compared with women aged 25 to 39 years (15.1%). A significantly lower delivery rate per stimulation and delivery rate per retrieval was found in women aged 40 to 43 and 44 to 45 years when compared with women aged 25 to 39 years. CONCLUSIONS: Success rates for IVF and GIFT decline significantly in women > 40 years old. Women aged > or = 44 years are unlikely to benefit from the use of IVF and GIFT. 相似文献
Recent work on phase equilibria diagrams has shown that periclase can take R+3 (Cr+3, Al+3, and Fe+3) in solid solution at elevated temperatures. In order to retain electrical neutrality, 2R+3 and a vacancy replaces 3Mg+2 in the periclase lattices. When Li+1 is added to MgO/R2O3 compositions, one Li+1 and one R+3 replaces 2 Mg+2 to form a solid solution which is stable at room temperature. These periclase solid solutions are more stable under conditions of temperature fluctuations and hydration than periclase/R2O3 solid solutions without lithia. 相似文献
In 4 experiments 82 university students formed mental images of pairs of named objects touching and interacting in some way. On half of the trials, one member of the pair was imaged such that it was at a small subjective size; on the remaining half of the trials, both objects were imaged at normal relative sizes. Ss rated their images in terms of vividness. Results of an unexpected memory test presented after all the items had been rated reveal poorer recall of words encoded as smaller images. This result was not due to differences in imaginal relations between the imaged objects in the 2 conditions, nor was it due to greater ease in constructing images including a reduced member. In addition, pairs including a subjectively tiny image were rated as less vivid than pairs including images only of normally sized objects. A regression analysis indicated that the memory deficit was due to size per se and was not a consequence of differences in vividness induced by the size manipulation. (French summary) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
We present an algorithm that explicitly utilizes the wavelength dependence of tissue optical properties for diffuse optical tomography. We have previously shown that the method gives superior separation of absorption and scattering. Here the technique is described and tested in detail, and optimum wavelength sets for a broad range of chromophore combinations are discovered and analyzed. 相似文献
Two promising technologies cosidered for the Beyond 5G networks are the terahertz and nano-technologies. Besides other possible application areas they hold the commitment to numerous new nano-scale solutions in the biomedical field. Nano-technology, as the name implies, examines the construction and design of nano-sized materials. These two interconnected emerging technologies have the potential to find application in quite many areas, one of the most importan being healthcare. This overview paper discusses the specifics of these technologies, their most important characteristics and introduces some of the trends for their application in the healthcare sector. In the first section terahertz frequency radio waves and their specific properties depending on the surrounding environment are discussed, followed by an introduction to nano-scale communications. Terahertz waves mandate the use of nano-scale antennas, which in turn brings us to the concept of nano-scale nodes. Nano-scale nodes are units that can perform the most basic functions of nano-machines and inter-nano-machine communications, which allow distributed nano-machines to perform more complex functions. Beyond 5G the development of these nano-communications is expected to lead to the emergence of new complex network systems. In the second part of this paper the paradigms of the Internet of Nano Things, molecular commnications and the Internet of Bio-Nano Things are discussed followed by details on their integration in healthcare related applications. The main goal of the article is to provide an introduction to these intriguing issues discussing advanced nano-technology enablers for Beyond 5G networks such as terahertz and molecular communications, nano-communications between nano-machines and the Internet of Bio-Nano-Things in light of health related applications.