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31.
32.
Qiyong Han Xiaodong Zhang Dong Chen Pengfei Wang 《Metallurgical and Materials Transactions B》1988,19(4):617-622
The equilibrium Ca3P2(s) = 3[Ca] + 2[P] was studied at 1600 ° by equilibrating liquid iron, saturated with Ca3P2, and contained in a TiN crucible, with Ca vapor. The source of Ca was liquid Ca contained in an Mo crucible, and the vapor
pressure of Ca was varied by varying the position of the Mo crucible in the temperature gradient of a vertical tube furnace.
A least-squares analysis of the data gave and. The simultaneous equilibria CaO(s) = [Ca] + [O] and CaS(s) = [Ca] + [S] were studied at 1600 ° by equilibrating liquid iron, contained in a pressed and sintered CaO-CaS crucible with
Ca vapor. The advantage of this technique is that two equilibrium constants,K
cas andK
cao, and two interaction coefficients, and can be determined from one set of experiments. It was determined that, at 1600 °,K
cas = 5.9 × 10−8
K
cao = 5.5 × 10−9,, and.
Formerly Graduate Students 相似文献
33.
34.
35.
Silicon - In this paper, an analytical model for negative capacitance double gate field effect transistor (NC-DG-FET) is proposed. This model includes interface traps and temperature effects, which... 相似文献
36.
Maria Buuales Maria Cristina Ballesteros-Briones Manuela Gonzalez-Aparicio Sandra Hervas-Stubbs Eva Martisova Uxua Mancheo Ana Ricobaraza Sara Lumbreras Cristian Smerdou Ruben Hernandez-Alcoceba 《International journal of molecular sciences》2021,22(8)
Immune checkpoint inhibitors (ICIs) have demonstrated remarkable efficacy in a growing number of malignancies. However, overcoming primary or secondary resistances is difficult due to pharmacokinetics issues and side effects associated with high systemic exposure. Local or regional expression of monoclonal antibodies (mAbs) using gene therapy vectors can alleviate this problem. In this work, we describe a high-capacity adenoviral vector (HCA-EFZP-aPDL1) equipped with a mifepristone-inducible system for the controlled expression of an anti-programmed death ligand 1 (PD-L1) blocking antibody. The vector was tested in an immune-competent mouse model of colorectal cancer based on implantation of MC38 cells. A single local administration of HCA-EFZP-aPDL1 in subcutaneous lesions led to a significant reduction in tumor growth with minimal release of the antibody in the circulation. When the vector was tested in a more stringent setting (rapidly progressing peritoneal carcinomatosis), the antitumor effect was marginal even in combination with other immune-stimulatory agents such as polyinosinic-polycytidylic acid (pI:C), blocking mAbs for T cell immunoglobulin, mucin-domain containing-3 (TIM-3) or agonistic mAbs for 4-1BB (CD137). In contrast, macrophage depletion by clodronate liposomes enhanced the efficacy of HCA-EFZP-aPDL1. These results highlight the importance of addressing macrophage-associated immunoregulatory mechanisms to overcome resistance to ICIs in the context of colorectal cancer. 相似文献
37.
H. B. Wu Z. T. Fan N. Y. Huang X. P. Dong X. F. Tian 《Journal of Materials Engineering and Performance》2005,14(1):132-135
The magnesium (Mg) alloy low-pressure expendable pattern casting (EPC) process is a newly developed casting technique combining
the advantages of both EPC and low-pressure casting. In this article, metal filling and the effect of the flow quantity of
inert gas on the filling rate in the low-pressure EPC process are investigated. The results showed that the molten Mg alloy
filled the mold cavity with a convex front laminar flow and the metal-filling rate increased significantly with increasing
flow quantity when flow quantity was below a critical value. However, once the flow quantity exceeded a critical value, the
filling rate increased slightly. The influence of the flow quantity of inert gas on melt-filling rate reveals that the mold
fill is controlled by flow quantity for a lower filling rate, and, subsequently, controlled by the evaporation of polystyrene
and the evaporation products for higher metal velocity. Meanwhile, the experimental results showed that the melt-filling rate
significantly affected the flow profile, and the filling procedure for the Mg alloy in the low-pressure EPC process. A slower
melt-filling rate could lead to misrun defects, whereas a higher filling rate results in folds, blisters, and porosity. The
optimized filling rate with Mg alloy casting is 140 to 170 mm/s in low-pressure EPC. 相似文献
38.
A lignite (C, 67.4 wt%) was depolymerized with phenol, p-nitrophenol and o-chlorophenol using sulphuric acid as catalyst. The solubility of the lignite was enhanced by these treatments, with phenol being the most reactive reagent whereas p-nitrophenol was the least reactive. The distribution of nitro- and chloro-groups in the solubilized products was investigated by infrared spectrometry and it was found that these groups were redistributed among the pyridine- and methanol-soluble materials. It is suggested that benzene-soluble material is produced by self-depolymerization of coal or by degradation of pyridine- and methanol-soluble material. 相似文献
39.
Electron Emission from Barium Strontium Titanate Ceramics 总被引:1,自引:0,他引:1
Shutao Chen Xianlin Dong Shuxin Zheng Ziqiu Zhu Chuanxiang Tang 《Journal of the American Ceramic Society》2006,89(7):2118-2122
This paper focuses on understanding the influence of materials' properties on the ferroelectric electron emission. Ferroelectric ( x =1.0 and 0.8) and paraelectric ( x =0.67 and 0.5) compositions of barium strontium titanate (Ba x Sr(1− x ) TiO3 ) system were chosen for study based on their different ferroelectric and dielectric properties. Similar emission current waveforms were obtained from four compositions with negative triggering voltage applied to the rear electrode of the samples. It was difficult to explain the experimental results using the spontaneous polarization-switching model. The mechanism of electron emission from Ba x Sr(1− x ) TiO3 ceramics was ascertained to surface plasma emission. 相似文献
40.