Multihour engineering and traffic routing optimization in hierarchical telephone networks

Classical hierarchical routing in telephone networks is extended to a wider class called out-of-chain routing in such a way that some useful properties of hierarchical routing are retained. This new routing pattern offers more potential paths than the fixed hierarchical one and can be introduced as a dynamic routing where the fixed alternate sequences change at some predetermined instants during the day. The effect of this new routing pattern on the network performances is examined. The main topic of this paper is to present heuristic methods used to optimise such routings in large networks. We show on artificial networks that the throughput of a given network can be significantly improved by suitable routing choices. We demonstrate that the integration of routing changes within a multihour dimensioning process is possible but the lack of realistic data does not permit at this time to quantify the value of routing optimization on real networks.     

Chromosome comparison between populations of the collared peccary, Tayassu tajacu, raised in captivity

The collared peccary (Tayassu tajacu) is widely distributed over the American continent, being found from the south of the USA to the north of Argentina. In Brazil, it is spread all over the country, being one of the potential species to be raised in captivity. Therefore, the cytogenetic techniques could be a potential tool for reproductive monitoring of animals raised in captivity, mainly when destined for commercial purposes. This study had the objective of determining the chromosome number of two populations raised in captivity and characterizing them by GTG banding. For this purpose, an analysis was made of mitotic metaphases obtained from lymphocyte cultures made from blood samples of 11 animals, six of which from the Northeast and five from the North of Brazil. The results of this analysis showed the same karyotype pattern for the species (2n=30 chromosomes and NF=48), besides corresponding to the South American pattern of the species, i.e., without a translocation between autosomes 1 and 8, chromosome X acrocentric, and no differences were found between the two populations studied. However, chromosomal polymorphisms were observed compared to data from the literature on populations from North and South America.     

Inhibition et mémoire de travail : effet d'une privation aigu? de sommeil sur une tache de génération aléatoire.

The literature contains inconsistent data on the effects of acute sleep deprivation on the superior cognitive functions. The primary purpose of this study is to determine the effectiveness of inhibition, one of the functions of the working memory executive centre (EC), over an extended, 36-hour waking period. Inhibition is a cognitive mechanism whereby individuals ignore non-relevant information recorded in their working memory. We also tested the effects of a 36- hour period of acute sleep deprivation on simple reaction time. Twelve young, healthy volunteers (M=21.5 years, ?=2.3) performed a random generation task involving letters and a simple reaction time psychomotor test over four sessions held at 10-hour intervals. Each participant was assigned a "constant routine." Participants were kept awake in a prone position within a room whose environment was held strictly constant (light, noise, temperature, meals, etc.). This control procedure provided assurance that any variation in participant performance was solely caused by sleep deprivation. The random generation task, nearly two minutes in length, consisted in verbally producing a sequence of 100 letters in a random fashion (i.e. by inhibiting, for example, alphabetical order) and by keeping to a set rhythm... (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Cellular and subcellular localization of transforming growth factor-alpha and epidermal growth factor receptor in normal and diseased human and hamster pancreas

Four normal pancreas, 8 chronic pancreatitis specimens, and 30 non-endocrine pancreatic tumors from humans and 6 normal and 6 induced pancreatic cancers in hamsters were examined immunohistochemically by antibodies against human transforming growth factor-alpha (TGF-alpha) and epidermal growth factor receptor (EGFR). Two normal pancreas and two pancreatic cancer specimens from each species were also studied immunoelectron microscopically by the immunogold method. In chronic pancreatitis, the reactivity and intensity of the staining with both antibodies were much greater in ductal/ductular cells than in the normal pancreas. All 30 pancreatic cancers reacted with both antibodies with a variable degree of reactivity and staining intensity. No correlation was found between the histological type of tumors, the degree of tumor differentiation, and the incidence and patterns of reactivity of either antibody. Immunoelectron microscopically, both EGFR and TGF-alpha were demonstrated primarily on the basal membrane. In the normal hamster pancreas, TGF-alpha was overexpressed in the alpha-cells but not in any other islet cells. Both TGF-alpha and EGFR were marginally detectable in the exocrine pancreas and in induced pancreatic lesions. This is the first demonstration of subcellular localization of TGF-alpha and EGFR in the normal and diseased human and hamster pancreas.     

Design of an isolated pig heart preparation for positron emission tomography and magnetic resonance imaging

RATIONALE AND OBJECTIVES: Validation of new positron emission tomography (PET) tracers or magnetic (MR) imaging contrast agents is based on isolated rodent heart preparations. The use of larger animals could provide a more direct validation using the devices used for humans. METHODS: An isolated pig heart preparation has been developed and adapted to the technical constraints of whole body PET and MR imaging. This preparation could be used either in the Langendorff or working mode after selective cannulation of both coronary arteries. RESULTS: The authors showed that quantification of regional kinetics of PET tracers was possible using this preparation by measuring fluorine-18-labeled deoxyglycose (18FDG) kinetics in remote and ischemic territories. Experiments using MR imaging contrast agents, for myocardial perfusion, demonstrated the ability of this preparation to accurately validate these contrast agents over a wide range of flow rates. CONCLUSIONS: An isolated pig heart preparation could be developed to fulfill the constraints of PET and MR imaging, and proved useful for the study of the distribution of different tracers or contrast media developed for functional cardiac imaging in humans.     

Short cue presentations encourage advance task preparation: A recipe to diminish the residual switch cost.

In the task-switching literature, it has frequently been demonstrated that although advance task preparation reduces the switch cost, it never really eliminates the switch cost. This remaining residual switch cost received much attention, and it has been argued that advance preparation is restricted in nature. In the present study, the role of task-cue presentation in the establishment of the residual switch cost was investigated. In 4 experiments, the cue was removed during the preparation interval, and it was hypothesized that this would encourage participants to complete advance task preparation. The results of all 4 experiments provided support for this hypothesis: When the cue was presented for a short time and then removed, the residual switch cost completely disappeared. This was found for different cue types. Furthermore, Experiment 3 demonstrated that it was not the presence of the cue itself but merely differences in advance task preparation that caused the effects. This suggests that advance task preparation is not as restricted in nature as previously assumed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

How far can one compress digital fault records? Analysis of a matching pursuit-based algorithm

In this paper, we verify how far electric disturbance signals can be compressed without compromising the analysis of encoded fault records. A recently proposed compression algorithm, referred to as Damped Sinusoidal Matching Pursuit (DSMP) has the remarkable feature of obtaining both compact and physically interpretable representations. However, for fault analysis applications, one is primarily interested in how accurate can be the analysis performed on compressed signals, instead of evaluating mean-squared error figures. Unlike previous works in digital fault records compression, the performance of the DSMP compression method is evaluated using a protocol based on fault analysis procedures commonly performed by expert engineers. This protocol is applied for comparing the results obtained in the analysis of both uncompressed records and their compressed versions at different compression ratios. The results show that the DSMP is a reliable compression system since it achieves high compression ratios (6.4:1) without causing fault analysis misinterpretation.