The Nexus of Corporate Entrepreneurship and Radical Innovation

This paper explores the linkage between the entrepreneurial orientation of established firms and the development of radical innovation. Through five case studies in firms involved in radical innovation, three propositions are developed, suggesting that proactiveness, risk‐taking and autonomy stimulate the development of radical innovation, whereas competitive aggressiveness does not necessarily do so, as radical innovations are directed towards the creation of entirely new arenas of business, where existing competitors are not present.     

Partial summations of stationary sequences of non-Gaussian random variables

The distribution of the sum of a finite number of identically distributed random variables is in many cases easily determined given that the variables are independent. The moments of any order of the sum can always be expressed by the moments of the single term without computational problems. However, in the case of dependency between the terms even calculation of a few of the first moments of the sum presents serious computational problems.By use of computerized symbol manipulations it is practicable to obtain exact moments of partial sums of stationary sequences of mutually dependent lognormal variables or polynomials of standard Gaussian variables. The dependency structure is induced by specifying the autocorrelation structure of the sequence of standard Gaussian variables. Particularly useful polynomials are the Winterstein approximations that distributionally fit with non-Gaussian variables up to the moments of the fourth order [Winterstein, S. R. Nonlinear vibration models for extremes and fatigue. J. Engng Mech. ASCE 114 (1988) 1772–1790]¹. A method to obtain the Winterstein approximation to a partial sum of a sequence of Winterstein approximations is explained and results are given for different autocorrelation functions of the generic Gaussian sequence.The primary purpose of the investigation is to provide a tool for judging the validity of the central limit theorem argument in specific applicational situations occurring in stochastic mechanics, that is, to judge the speed of convergence of the distribution of a sum (or an integral) of mutually dependent random variables to the Gaussian distribution. The paper is closely related to the work in Ditlevsen et al. [Ditlevsen, O., Mohr, G. & Hoffmeyer, P. Integration of non-Gaussian fields. Prob. Engng Mech 11 (1996) 15–23]².     

A pragmatic approach to wind farm simulations using the dynamic wake meandering model

This paper presents a computationally efficient method for using the dynamic wake meandering model to conduct simulations of wind farm power production. The method is based on creating a database, which contains the time and rotor‐averaged wake effect at any point downstream of a wake‐emitting turbine operating in arbitrary ambient conditions and at an arbitrary degree of wake influence. This database is later used as a look‐up table at runtime to estimate the operating conditions at all turbines in the wind farm, thus eliminating the need to run the dynamic wake meandering model at runtime. By using the proposed method, the time required to conduct wind farm simulations is reduced by three orders of magnitude compared with running the standalone dynamic wake meandering model at runtime. As a result, the wind farm production dynamics for a farm of 100 turbines at 10,000 different sets of ambient conditions run on a normal laptop in 1 h. The method is validated against full scale measurements from the Smøla and OWEZ wind farms, and fair agreement is achieved. Copyright © 2014 John Wiley & Sons, Ltd.     

A Novel Nanoprobe for Multimodal Imaging Is Effectively Incorporated into Human Melanoma Metastatic Cell Lines

To facilitate efficient drug delivery to tumor tissue, several nanomaterials have been designed, with combined diagnostic and therapeutic properties. In this work, we carried out fundamental in vitro and in vivo experiments to assess the labeling efficacy of our novel theranostic nanoprobe, consisting of glycogen conjugated with a red fluorescent probe and gadolinium. Microscopy and resazurin viability assays were used to study cell labeling and cell viability in human metastatic melanoma cell lines. Fluorescence lifetime correlation spectroscopy (FLCS) was done to investigate nanoprobe stability. Magnetic resonance imaging (MRI) was performed to study T₁ relaxivity in vitro, and contrast enhancement in a subcutaneous in vivo tumor model. Efficient cell labeling was demonstrated, while cell viability, cell migration, and cell growth was not affected. FLCS showed that the nanoprobe did not degrade in blood plasma. MRI demonstrated that down to 750 cells/μL of labeled cells in agar phantoms could be detected. In vivo MRI showed that contrast enhancement in tumors was comparable between Omniscan contrast agent and the nanoprobe. In conclusion, we demonstrate for the first time that a non-toxic glycogen-based nanoprobe may effectively visualize tumor cells and tissue, and, in future experiments, we will investigate its therapeutic potential by conjugating therapeutic compounds to the nanoprobe.     

Lead Free Ammunition without Toxic Propellant Gases

Environmental and health considerations have encouraged the development of ammunition with substitutes for lead and other heavy metals. In general, the emission products from munitions containing nitro‐based propellants are highly complex mixtures of gases, vapors, and solid particles. The major combustion products are H₂O, CO, CO₂, H₂, and N₂. In addition, compounds including hydrogen cyanide (HCN), ammonia (NH₃), methane (CH₄), nitrogen oxides, benzene, acrylonitrile, toluene, furan, aromatic amines, benzopyrene, and various polycyclic aromatic hydrocarbons are detected in minor concentrations. Many of the identified chemical species have severe toxicological properties, and some of the compounds do even have mutagenic effects. Gun smoke emission is a concern because its exposure to humans may be substantial during military and civilian police training, as respiratory protection equipment is not routinely worn. In this work we study the compositions of some of the main decomposition products, experimentally as well as theoretically. The concept of frozen equilibrium at around 1500–2000 K appears to apply for CO, CO₂, and H₂. However, the trace species in the combustion mixtures appear theoretically to be present in negligible concentrations. Our measured results are many orders of magnitude higher than theoretical results in open space. We forecast that future development of gun powder will focus on reducing the amount of toxic trace species.     

Oil Spill Detection in Radarsat and Envisat SAR Images

We present algorithms for automatic detection of oil spills in synthetic aperture radar (SAR) images. The algorithms consist of three main parts, namely: 1) detection of dark spots; 2) feature extraction from the dark spot candidates; and 3) classification of dark spots as oil spills or look-alikes. The algorithms have been trained on a large number of Radarsat and Envisat Advanced Synthetic Aperture Radar (ASAR) images. The performance of the algorithm is compared to manual and semiautomatic approaches in a benchmark study using 59 Radarsat and Envisat images. The algorithms can be considered to be a good alternative to manual inspection when large ocean areas are to be inspected     

Hydro reservoir handling in Norway before and after deregulation

The Norwegian Energy Act that came into force in 1991 deregulated the electricity market and removed the former obligation power companies had to supply electricity to the geographical area they were responsible for. Hence producers can supply electricity on the basis of profitability. In 2007 the Energy Act was evaluated by the Government. As a part of this, a study concerning hydro reservoir handling before and after deregulation was carried out by SINTEF. Public statistics show that average hydro reservoir levels measured in per cent of reservoir capacity have been reduced after 1990. We have used the power-market model EMPS¹ (EFI's Multi-area Power-market Simulator) to analyze if this reduction can be explained by natural variation in climatic variables or by structural changes that have occurred after 1990. Simulation results show that the reduced reservoir levels cannot be explained by natural variation in climatic variables. Structural changes such as increased transmission capacities can, however, explain some of the reduction. Our study does not indicate that the present reservoir handling gives reservoir levels that are too low. In this paper we also describe the stochastic dynamic optimization problem for long-term hydropower scheduling, and we explain how this problem actually is solved by the EMPS model.     

The fake of reliability measures as absolutes

It is claimed that any reliability measure defined in connection with a limit state theory of a high reliability technological system is a purely formal comparative measure of safety. It only makes sense to make comparisons within classes of “similar” technological systems which are all accessible to the same theory. Interpretation of calculated formal failure probabilities as predictions of real failure rates are generally not justified.     

Influence of a glass-water interface on the on-axis trapping of micrometer-sized spherical objects by optical tweezers

A systematic study of the influence of a glass-water interface on the on-axis trapping of micrometer-sized spherical objects by optical tweezers is presented. The ways in which the escape force and the trapping position, as well as the stiffness of the trap, depend on the focusing depth, the numerical aperture, and the degree of overfilling of the objective entrance pupil are investigated. It is concluded, among other things, that objectives with the highest numerical aperture and the use of large degrees of overfilling do not always provide the optimum trapping conditions at finite depths.     

Duration of visit to critical set by Gaussian process

The exact distribution of the duration of a visit of a stationary Gaussian process to an interval is not known except for processes with certain simple auto-dependence properties of Markov type. However, the exact mean is known without any restrictive dependence assumptions.Since the duration distribution, or, equivalently, the first outpassage time distribution, is needed in several engineering applications, there is an interest in making the necessary simplifying assumptions concerning the auto-dependence properties of the process. For smooth wide band processes comparisons with simulated results show that it improves the accuracy of the results considerably if a Markov type property, called 0-lag dependence of the first passage time, is imposed on the Slepian model process rather than if it is imposed directly on the original stationary process. The Slepian model process describes the distributional behaviour of the original stationary and ergodic Gaussian process after a crossing into the interval.The resulting duration distribution formulas involve multiple integrals and are therefore numerically complicated. For practical applications a simple three-parameter distribution family is suggested such that it possesses the exact mean. The three parameters may be estimated by fit to some few points obtained by numerical calculation of the multiple integrals.