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31.
We consider adaptive stabilization for a class of nonlinear second-order systems. Interpreting the system states as position and velocity, the system is assumed to have unknown, nonparametric position-dependent damping and stiffness coefficients. Lyapunov methods are used to prove global convergence of the adaptive controller. Furthermore, the controller is shown to be able to reject constant disturbances and to asymptotically track constant commands. For illustration, the controller is used to stabilize the van der Pol limit cycle, the Duffing oscillator with multiple equilibria, and several other examples 相似文献
32.
Alexander V. Bernstein Alexander P. Kuleshov 《International Journal of Software and Informatics》2013,7(3):359-390
One of the ultimate goals of Manifold Learning (ML) is to reconstruct an unknown nonlinear low-dimensional Data Manifold (DM) embedded in a high-dimensional observation space from a given set of data points sampled from the manifold. We derive asymptotic expansion and local lower and upper bounds for the maximum reconstruction error in a small neighborhood of an arbitrary point. The expansion and bounds are defined in terms of the distance between tangent spaces to the original DM and the Reconstructed Manifold (RM) at the selected point and its reconstructed
value, respectively. We propose an amplification of the ML, called Tangent Bundle ML, in which proximity is required not only between the DM and RM but also between their tangent spaces. We present a new geometrically
motivated Grassman & Stiefel Eigenmaps algorithm that solves this problem and gives a new solution for the ML also. 相似文献
33.
Concentration polarization-enhanced radical graft polymerization, a facile surface modification technique, was examined as an approach to reduce bacterial deposition onto RO membranes and thus contribute to mitigation of biofouling. For this purpose an RO membrane ESPA-1 was surface-grafted with a zwitterionic and negatively and positively charged monomers. The low monomer concentrations and low degrees of grafting employed in modifications moderately reduced flux (by 20-40%) and did not affect salt rejection, yet produced substantial changes in surface chemistry, charge and hydrophilicity. The propensity to bacterial attachment of original and modified membranes was assessed using bacterial deposition tests carried out in a parallel plate flow setup using a fluorescent strain of Pseudomonas fluorescens. Compared to unmodified ESPA-1 the deposition (mass transfer) coefficient was significantly increased for modification with the positively charged monomer. On the other hand, a substantial reduction in bacterial deposition rates was observed for membranes modified with zwitterionic monomer and, still more, with very hydrophilic negatively charged monomers. This trend is well explained by the effects of surface charge (as measured by ζ-potential) and hydrophilicity (contact angle). It also well correlated with force distance measurements by AFM using surrogate spherical probes with a negative surface charge mimicking the bacterial surface. The positively charged surface showed a strong hysteresis with a large adhesion force, which was weaker for unmodified ESPA-1 and still weaker for zwitterionic surface, while negatively charged surface showed a long-range repulsion and negligible hysteresis. These results demonstrate the potential of using the proposed surface- modification approach for varying surface characteristics, charge and hydrophilicity, and thus minimizing bacterial deposition and potentially reducing propensity biofouling. 相似文献
34.
This paper considers the fixed-structure, discrete-time mixed H 2 / H X controller synthesis problem in the delta operator (difference operator) framework. The differential operator and shift operator versions of the problem are reviewed for comparison, and necessary conditions are derived for all three formulations. A quasi-Newton/continuation algorithm is then used to obtain approximate solutions to these equations. Controllers are synthesized for two numerical examples, and the performance of the algorithm on the differential, difference and shift operator versions of the problems is compared. 相似文献
35.
Zvolensky Michael J.; Marshall Erin C.; Johnson Kirsten; Hogan Julianna; Bernstein Amit; Bonn-Miller Marcel O. 《Canadian Metallurgical Quarterly》2009,17(1):31
The present investigation examines anxiety sensitivity, distress tolerance, and fear reactivity to bodily sensations in relation to Coping and Conformity marijuana use motives among a sample of young adult marijuana users (n = 135; 46.7% women; Mage = 20.45, SD = 5.0). After controlling for current marijuana use frequency (past 30 days), daily cigarette smoking rate, average volume of alcohol used over the past year, negative affectivity, and other marijuana use motives, anxiety sensitivity was significantly and uniquely associated with Coping and Conformity motives for marijuana use. Distress tolerance evidenced significant and unique incremental relations to Coping motives, whereas fear reactivity to bodily sensations was unrelated to any marijuana use motive. These results provide novel information related to the role of emotional sensitivity and tolerance factors as they pertain to specific types of motives for marijuana use among young adults. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
36.
Estimation of human dose of staphylococcal enterotoxin A from a large outbreak of staphylococcal food poisoning involving chocolate milk 总被引:14,自引:0,他引:14
M L Evenson M W Hinds R S Bernstein M S Bergdoll 《International journal of food microbiology》1988,7(4):311-316
An outbreak of gastroenteritis in a school district in the United States was determined to be staphylococcal food poisoning due to 2% chocolate milk containing staphylococcal enterotoxin A (SEA). Twelve one-half pint (approx 0.28 l) cartons of the 2% chocolate milk from this outbreak were analyzed for the quantity of SEA present in the milk. The amount of SEA in the cartons varied from 94 to 184 ng with the average being 144 ng (mean = 139 +/- 45). The attack rate for vomiting among those who consumed more than one carton was greater (38.3%) than among those who consumed only one carton (31.5%) with the highest attack rate among those who consumed three or more cartons (44.4%). 相似文献
37.
Ethan S. Pickerill Rebecca P. Kurtz Aaron Tharp Paula Guerrero Sanz Munni Begum Douglas A. Bernstein 《Yeast (Chichester, England)》2019,36(11):669-677
RNA can be modified in over 100 distinct ways, and these modifications are critical for function. Pseudouridine synthases catalyse pseudouridylation, one of the most prevalent RNA modifications. Pseudouridine synthase 7 modifies a variety of substrates in Saccharomyces cerevisiae including tRNA, rRNA, snRNA, and mRNA, but the substrates for other budding yeast Pus7 homologues are not known. We used CRISPR-mediated genome editing to disrupt Candida albicans PUS7 and find absence leads to defects in rRNA processing and a decrease in cell surface hydrophobicity. Furthermore, C. albicans Pus7 absence causes temperature sensitivity, defects in filamentation, altered sensitivity to antifungal drugs, and decreased virulence in a wax moth model. In addition, we find C. albicans Pus7 modifies tRNA residues, but does not modify a number of other S. cerevisiae Pus7 substrates. Our data suggests C. albicans Pus7 is important for fungal vigour and may play distinct biological roles than those ascribed to S. cerevisiae Pus7. 相似文献
38.
Badeau R.W. Bahar R.I. Bernstein D. Biro L.L. Bowhill W.J. Brown J.F. Case M.A. Castelino R.W. Cooper E.M. Delaney M.A. Deverell D.R. Edmonson J.H. Ellis J.J. Fischer T.C. Fox T.F. Gowan M.K. Gronowski P.E. Herrick W.V. Jain A.K. Meyer J.E. Miner D.G. Partovi H. Peng V. Preston R.P. Somanathan C. Stamm R.L. Thierauf S.C. Uhler G.M. Wade N.D. Wheeler W.R. 《Solid-State Circuits, IEEE Journal of》1992,27(11):1585-1598
A macropipelined CISC microprocessor was implemented in a 0.75-μm CMOS 3.3-V technology. The 1.3-million-transistor custom chip measures 1.62×1.46 cm2 and dissipates 16.3 W. The 100-MHz parts were benchmarked at 50 SPEC marks. The on-chip clocking system and several high-performance logic and circuit techniques are described. Macroinstruction handling, micropipeline management, and control store structures highlight the design architecture. The hierarchical array organization and fast tag comparison technique of the primary cache are discussed. Power estimation procedures are outlined, and the results are compared to measurements. Physical design and verification methods, and CAD tools are also described. After extensive functional verification efforts are described, chip and system test results are presented 相似文献
39.
40.
PP Sayeski MS Ali DJ Semeniuk TN Doan KE Bernstein 《Canadian Metallurgical Quarterly》1998,78(1-3):19-29
It has been 100 years since the discovery of renin by Tigerstedt and Bergman. Since that time, numerous discoveries have advanced our understanding of the renin-angiotensin system, including the observation that angiotensin II is the effector molecule of this system. A remarkable aspect of angiotensin II is the many different physiological responses this simple peptide induces in different cell types. Here, we focus on the signal transduction pathways that are activated as a consequence of angiotensin II binding to the AT1 receptor. Classical signaling pathways such as the activation of heterotrimeric G proteins by the AT1 receptor are discussed. In addition, recent work examining the role of tyrosine phosphorylation in angiotensin II-mediated signal transduction is also examined. Understanding how these distinct signaling pathways transduce signals from the cell surface will advance our understanding of how such a simple molecule elicits such a wide variety of specific cellular responses. 相似文献