首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   737篇
  免费   4篇
  国内免费   3篇
电工技术   29篇
化学工业   70篇
金属工艺   7篇
机械仪表   11篇
建筑科学   36篇
能源动力   28篇
轻工业   39篇
水利工程   22篇
石油天然气   3篇
无线电   101篇
一般工业技术   87篇
冶金工业   118篇
原子能技术   2篇
自动化技术   191篇
  2023年   2篇
  2022年   16篇
  2021年   20篇
  2020年   19篇
  2019年   22篇
  2018年   16篇
  2017年   14篇
  2016年   20篇
  2015年   4篇
  2014年   18篇
  2013年   71篇
  2012年   16篇
  2011年   35篇
  2010年   17篇
  2009年   22篇
  2008年   28篇
  2007年   15篇
  2006年   15篇
  2005年   21篇
  2004年   16篇
  2003年   8篇
  2002年   13篇
  2001年   10篇
  2000年   8篇
  1999年   11篇
  1998年   44篇
  1997年   48篇
  1996年   22篇
  1995年   26篇
  1994年   26篇
  1993年   17篇
  1992年   10篇
  1991年   6篇
  1990年   5篇
  1989年   9篇
  1988年   5篇
  1987年   7篇
  1986年   7篇
  1985年   3篇
  1984年   4篇
  1983年   4篇
  1982年   2篇
  1980年   3篇
  1979年   3篇
  1978年   4篇
  1977年   6篇
  1976年   7篇
  1974年   2篇
  1973年   5篇
  1971年   2篇
排序方式: 共有744条查询结果,搜索用时 0 毫秒
21.
Zhang et al. (Water Resour Manag doi:10.1007/s11269-012-0182-2, 2012) studied the impacts of climate change and human activities on the runoff for the Huifa River basin. They employed a soil and water assessment tool (SWAT), which was calibrated for the baseline period 1956–1964, and then used to reconstruct the natural runoff for the climate change period 1965–2000. Results showed that both climate change and human activities decrease the observed runoff. Climate change impacts on annual runoff were ?37.7, ?59.5, +36.9, and ?45.2 mm/a for 1965–1975, 1976–1985, 1986–1995, and 1996–2005 respectively, compared with the baseline period 1956–1964. Human activities decreased runoff and caused a relatively larger magnitude impact than those of climate change after 1985. Human activities decreased the annual runoff by ?32.9, ?46.8, ?67.8, and ?54.9 mm/a for 1965–1975, 1976–1985, 1986–1995, and 1996–2005 respectively. Human activities further decreased runoff in wet years due to regulation and storage of water projects.  相似文献   
22.
Over the last decade, evolutionary and meta-heuristic algorithms have been extensively used as search and optimization tools in various problem domains, including science, commerce, and engineering. Their broad applicability, ease of use, and global perspective may be considered as the primary reason for their success. The honey-bees mating process may also be considered as a typical swarm-based approach to optimization, in which the search algorithm is inspired by the process of real honey-bees mating. In this paper, the honey-bees mating optimization algorithm (HBMO) is presented and tested with few benchmark examples consisting of highly non-linear constrained and/or unconstrained real-valued mathematical models. The performance of the algorithm is quite comparable with the results of the well-developed genetic algorithm. The HBMO algorithm is also applied to the operation of a single reservoir with 60 periods with the objective of minimizing the total square deviation from target demands. Results obtained are promising and compare well with the results of other well-known heuristic approaches.  相似文献   
23.
    
Cardiovascular morbidity is the leading cause of death of obstructive sleep apnea (OSA) syndrome patients. Nocturnal airway obstruction is associated with intermittent hypoxia (IH). In our previous work with cell lines, incubation with sera from OSA patients induced changes in cell morphology, NF-κB activation and decreased viability. A decrease in beating rate, contraction amplitude and a reduction in intracellular calcium signaling was also observed in human cardiomyocytes differentiated from human embryonic stem cells (hESC-CMs). We expanded these observations using a new controlled IH in vitro system on beating hESC-CMs. The Oxy-Cycler system was programed to generate IH cycles. Following IH, we detected the activation of Hif-1α as an indicator of hypoxia and nuclear NF-κB p65 and p50 subunits, representing pro-inflammatory activity. We also detected the secretion of inflammatory cytokines, such as MIF, PAI-1, MCP-1 and CXCL1, and demonstrated a decrease in beating rate of hESC-CMs following IH. IH induces the co-activation of inflammatory features together with cardiomyocyte alterations which are consistent with myocardial damage in OSA. This study provides an innovative approach for in vitro studies of OSA cardiovascular morbidity and supports the search for new pharmacological agents and molecular targets to improve diagnosis and treatment of patients.  相似文献   
24.
    
The overall impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on our society is unprecedented. The identification of small natural ligands that could prevent the entry and/or replication of the coronavirus remains a pertinent approach to fight the coronavirus disease (COVID-19) pandemic. Previously, we showed that the phenolic compounds corilagin and 1,3,6-tri-O-galloyl-β-D-glucose (TGG) inhibit the interaction between the SARS-CoV-2 spike protein receptor binding domain (RBD) and angiotensin-converting enzyme 2 (ACE2), the SARS-CoV-2 target receptor on the cell membrane of the host organism. Building on these promising results, we now assess the effects of these phenolic ligands on two other crucial targets involved in SARS-CoV-2 cell entry and replication, respectively: transmembrane protease serine 2 (TMPRSS2) and 3-chymotrypsin like protease (3CLpro) inhibitors. Since corilagin, TGG, and tannic acid (TA) share many physicochemical and structural properties, we investigate the binding of TA to these targets. In this work, a combination of experimental methods (biochemical inhibition assays, surface plasmon resonance, and quartz crystal microbalance with dissipation monitoring) confirms the potential role of TA in the prevention of SARS-CoV-2 infectivity through the inhibition of extracellular RBD/ACE2 interactions and TMPRSS2 and 3CLpro activity. Moreover, molecular docking prediction followed by dynamic simulation and molecular mechanics Poisson–Boltzmann surface area (MMPBSA) free energy calculation also shows that TA binds to RBD, TMPRSS2, and 3CLpro with higher affinities than TGG and corilagin. Overall, these results suggest that naturally occurring TA is a promising candidate to prevent and inhibit the infectivity of SARS-CoV-2.  相似文献   
25.
    
Mosquito-borne Zika virus (ZIKV) became a real threat to human health due to the lack of vaccine and effective antiviral treatment. The virus has recently been responsible for a global outbreak leading to millions of infected cases. ZIKV complications were highlighted in adults with Guillain–Barré syndrome and in newborns with increasing numbers of congenital disorders ranging from mild developmental delays to fatal conditions. The ability of ZIKV to establish a long-term infection in diverse organs including the kidneys has been recently documented but the consequences of such a viral infection are still debated. Our study aimed to determine whether the efficiency of ZIKV growth in kidney cells relates to glucose concentration. Human kidney HK-2 cells were infected with different ZIKV strains in presence of normal and high glucose concentrations. Virological assays showed a decrease in viral replication without modifying entry steps (viral binding, internalization, fusion) under high glucose conditions. This decrease replication was associated with a lower virus progeny and increased cell viability when compared to ZIKV-infected HK-2 cells in normal glucose concentration. In conclusion, we showed for the first time that an elevated glucose level influences ZIKV replication level with an effect on kidney cell survival.  相似文献   
26.
In this paper, a linear viscoelastic material is considered as a dynamic system. From this point of view, a dynamic system identification method is developed for the determination of the relaxation or creep function of the material from dynamic experimental measurements. First, the relation between the relaxation or creep function and the transfer function of the system is established by assuming a model of rational functions of polynomials for the transfer function. Second, a discrete-time system analysis method is introduced to identify the order and parameters of the proposed model from the discretetime series of both the input and output signals. The numerical examples given show that the proposed procedure is reasonable and the model is accurate and efficient.  相似文献   
27.
28.
An automated technique is presented for the computation of the doping profiles that minimize the intrinsic fluctuations of various parameters induced by random doping fluctuations in semiconductor devices. The technique is based on the computation of the doping sensitivity functions of the parameters under consideration and the constrained minimization of the standard deviation of fluctuations by using the Lagrange multipliers technique. The technique is then applied to the minimization of the random doping induced fluctuations of the threshold voltage in 40-nm channel length MOSFET device.  相似文献   
29.
 A miniaturized torque sensor based on cable brake principle for the measurement of torque-characteristic of minimotors and micromotors has been developed. The first generation torque sensor enables the measurement of torque of minimotors in the range of μNm. Design principles and the production process are described. Experimental results show fair conformity with technical data for minimotors. Received: 30 October 1996 / Accepted: 14 November 1996  相似文献   
30.
Markov chains are a well-known stochastic process that provide a balance between being able to adequately model the system's behavior and being able to afford the cost of the model solution. The definition of stochastic temporal logics like continuous stochastic logic (CSL) and its variant asCSL, and of their model-checking algorithms, allows a unified approach to the verification of systems, allowing the mix of performance evaluation and probabilistic verification. In this paper we present the stochastic logic CSLTA, which is more expressive than CSL and asCSL, and in which properties can be specified using automata (more precisely, timed automata with a single clock). The extension with respect to expressiveness allows the specification of properties referring to the probability of a finite sequence of timed events. A typical example is the responsiveness property "with probability at least 0.75, a message sent at time 0 by a system A will be received before time 5 by system B and the acknowledgment will be back at A before time 7", a property that cannot be expressed in either CSL or asCSL. We also present a model-checking algorithm for CSLTA.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号