Propolis to Curb Lifestyle Related Disorders: An Overview

The natural products are gaining immense importance in the domain of nutrition to prevent various maladies and improve the quality of life. Among these, natural exudates are of significant worth as these biochemical compounds are released by various living entities having pharmacological properties for utilization in various drug developments. These natural exudates are the promising source for the discovery of new medications. Numerous bioactive moieties collected by honeybees from exudates and buds of particular trees and plants, considered to be utilized as defensive barrier with special reference to propolis. It generally contains numerous biochemical components, i.e., polyphenols, steroids, terpenoids, and amino acids. They also contain isoferulic acid, sinapinic acid, caffeic acid, and chrysin responsible for antibacterial perspectives. With special attention to propolis, it has been utilized in folk medicines due to several of its therapeutic activities, i.e., antioxidant, antidiabetic, anti-inflammatory, antiviral, and anticancer properties. In this context, it is extensively used in foodstuffs and beverages to improve health related disorders like inflammation, diabetes, heart disease, protects injured gums, and cancer insurgence. Moreover, it has been used to curtail stomatology, gastroenterology, skin lesions, and otorhinolaryngologic and respiration diseases.     

A computerized algorithm for milling non-convex pockets with numerically controlled machines

Advanced part programming languages like APT have the facility for stating pocket milling operations with one or more statements. However, these statements apply only to convex pockets. In this paper, an algorithm for machining non-convex pockets is described. This is done by defining one suitable edge of the polygon as a reference line and then defining a series of cutter paths parallel to it resulting in a continuous cutter path. The paper also describes the procedure for selecting reference line and cutter locations, the calculations involved and the computerization of the algorithm. Finally, it gives an illustrated example of a cutter path generated for a hypothetical component.     

Empirical correlation of estimating global solar radiation using meteorological parameters

An empirical model for the estimation of solar energy on the basis of Angstrom's model is proposed in this work. Seven regression equations are developed by using different meteorological parameters such as mean sunshine duration per hour, temperature, relative humidity, wind speed, and rainfall. The performance of the model is determined on the basis of statistical indicators like correlation coefficient(r), coefficient of determination (R²), root mean square error (RMSE), mean percentage error (MPE), and mean bias error (MBE). The results show that the equation with the highest value of r, R² and the least value of RMSE, MPE, and MBE provides better results.     

In vitro synergism of antimutagenic and antioxidant activities of Phoenix dactylifera fruit

The availability of total phenolics of date flesh (Pheonix dactylifera) in aqueous and acidified methanol and in vitro synergism of their antimutagenic and antioxidant activities were investigated. The antimutagenic activities of date flesh extracts tested against Salmonella strains TA-98 and TA-100 using Ames bacterial testing were in the range of 36.47 to 79.74% against the standard mutagens potassium dichromate and sodium azide. The antioxidant activities assessed as maximal inhibitory concentrations (IC₅₀) for DPPH radicals and linoleic acid peroxidation inhibition were 812.90 to 2,076.10 μg/mL and 54.43 to 80.89%, respectively. The total phenolic contents of date flesh extracts (35.76 to 114.09mg/g of gallic acid equivalents) were found to be correlated with the biological activities. Use of 0.5 N acidified methanol was efficient for extraction of phenolic compounds with retained antioxidant and antimutagen activities. Dates are a good candidate as a source for development of chemotherapeutic drugs, nutracueticals, and functional food ingredients.     

Mechanism of formation of urchin-like ZnO

Thin films composed of ZnO nanowires (NWs) hierarchically organized with an urchin-like 3D morphology were obtained by combining the electrochemical deposition and sphere lithography methods. Deposited on a transparent conductive oxide substrate (TCO), a monolayer of carboxylate modified polystyrene spheres organized with a hexagonal closed-packed structure played the role of a template. The spheres were activated in a solution of zinc chloride by the formation of bonds between the carboxylate terminals and the Zn²⁺ ions and were used as a template for the electrodeposition of vertically aligned ZnO NWs around them. Without this treatment, ZnO NWs were deposited only on the TCO substrate between the PS spheres. To reach a density of nanowires high enough to obtain the urchin morphology, the concentration of ZnCl₂ had to be at least equal to 2 M. It was also found, as soon as small grains of ZnO started to be electrodeposited on the polystyrene spheres that the spheres were no longer close packed. The space created between them increased with the increase in the number of small ZnO grains and the increase in their length, allowing the further growth of the nanowires between the spheres. As a result the initial round shape of the spheres was modified and the urchin-like ZnO exhibited an ellipsoidal shape.     

Evaluation of machinability and economic performance in cryogenic-assisted hard turning of α-β titanium: a step towards sustainable manufacturing

Abstract

Titanium, a difficult-to-cut material, consumes higher time and cost in removing material by machining to produce parts. Machining of Ti alloys has got serious attention owing to its reactive nature with tool materials at elevated temperature that aggravates tool wear. Reportedly, effective and efficient cooling and lubrication at the tool–work interface can ameliorate the machinability of Ti-alloys. In this perspective, this article interrogates the underlying mechanism of critical responses such as surface roughness, temperature, tool life and machining cost under dry, minimum quantity lubrication (MQL) and cryogenic liquid nitrogen (LN2) modes. The effect of cutting speeds and feed rates on such responses have been considered as a function of cooling strategy to standardize the cooling technique as the best alternative for machining. Cryogenic cooling seems to be preponderant regarding machining cost, temperature, surface roughness and tool life in hard turning of a–b titanium alloy. The feasibility of cryogenic cooling was investigated using the iso-response technique in comparison with dry and MQL-assisted hard turning. Experimental results revealed longer tool life and lower machining cost under cryogenic condition followed by MQL and dry machining. Moreover, cryogenic LN2 has been identified as an appropriate alternative to reduce the temperature and surface roughness. On contrary, dry turning evoked a high-temperature and rapid tool wear. In a nutshell, cryogenic assisted hard turning has acceded as a sustainable strategy from an environmental and economic perspective.     

The thermal modeling of a matrix heat exchanger using a porous medium and the thermal non-equilibrium model

Heat transfer and fluid flow characteristics through a porous medium were investigated using numerical simulations and experiment. For the numerical simulations two models were created: a two-dimensional numerical model and a Fluent™ computational fluid dynamics (CFD) porous media model. The experimental investigation consisted of a flow channel with a porous medium section that was heated from below by a heat source. The results of the numerical models were compared to the experimental data in order to determine the accuracy of the models. The numerical model was then modified to better simulate a matrix heat exchanger. This numerical model then generated temperature profiles that were used to calculate the heat transfer coefficient of the matrix heat exchanger and develop a correlation between the Nusselt number and the Reynolds number.     

Characterization of plasma propulsion by Nd:YAG laser

Significant propulsion parameters, specific impulse and coupling coefficient for the different metallic pendulums are presented. 4 N (99.99%) pure, solid targets are in the form of foils of aluminium, copper and gold. The targets are irradiated by Q-switched pulsed Nd:YAG laser (1064 nm, 10 mJ, 1.1 MW, 9-14 ns) under standard conditions of temperature and pressure. Plasma plume of these targets is also observed by employing CCD (BOSCH LTC0510, monochrome camera) based, computer controlled image capturing system and it was seen that expansion of plasma plume for oscillating targets is anisotropic in air. The results reveal that not only very high exhaust velocity of propellant 10⁶ m/s is achieved but also very specific impulse values of Al, Cu and Au targets (3.14 × 10⁶ s, 1.37 × 10⁷ s, 7.16 × 10⁵ s respectively) are obtained. Coupling coefficients are for Al, Cu and Au were 1.54 × 10³ (N-s/J), 1.88 × 10³ (N-s/J), and 1.08 × 10³ (N-s/J) respectively.     

Jatropha curcas: A potential crop for phytoremediation of coal fly ash

A greenhouse pot experiment was conducted to test the heavy metal phytoremediation capacity of Jatropha curcas from fly ash. Both natural accumulation by J. curcas and chemically enhanced phytoextraction was investigated. Plants were grown on FA and FA amended with fertile garden soil, in presence and absence of chemical chelating agent EDTA at 0.1 g kg⁻¹ and 0.3 g kg⁻¹ of soil. EDTA enhanced the uptake of all five elements (Fe, Al, Cr, Cu and Mn) tested. Fe and Mn were retained more in roots while Cu, Al and Cr were translocated more to the shoot. Metal accumulation index indicates that the effect of EDTA at 0.3 g kg⁻¹ was more pronounced than EDTA at 0.1 g kg⁻¹ in terms of metal accumulation. Biomass was enhanced up to 37% when FA was amended with GS. Heavy metal uptake was enhanced by 117% in root, 62% in stem, 86% in leaves when EDTA was applied at 0.3 g kg⁻¹ to FA amended with GS. Study suggest that J. curcas has potential of establishing itself on FA when provided with basic plant nutrients and can also accumulate heavy metals many folds from FA without attenuating plant growth.