A study of the effects of pavement ageing on binder deterioration

This paper discusses the ageing of asphalt binder of long-term pavement performance (LTPP) sites in Southeast Queensland. The effects of pavement age on binder deterioration were examined by performing ‘Shell’ sliding plate micro-viscometer laboratory tests in accordance with Australian and New Zealand Standard AS/NZS 2341.5: 1997. The tests were carried out on bituminous core samples obtained from the LTPP sites to determine the apparent viscosity of the asphalt binder. A binder deterioration model (BDM) was developed by establishing a relationship between the apparent viscosities of the binder with pavement age. The apparent viscosity data generated using the BDM were compared with that computed using the bitumen hardening model developed by Oliver (2003). The two models show a consistent trend in the binder deterioration, and the results were analysed statistically using regression analysis, Root Mean Square Error and t-test methods. The t-test shows that the data generated by the BDM have no significant deviation from the prediction by Oliver's model.     

Growth behavior comparison of Listeria monocytogenes between Type strains and beef isolates in raw beef

Food Science and Biotechnology - This study was conducted to compare the growth parameters of Listeria monocytogenes between beef isolates and Type strains in raw beef. Beef was artificially...     

Preloading using fill surcharge and prefabricated vertical drains for an airport

This paper presents the field measurements and analysis of a preloading project with the installation of prefabricated vertical drains (PVDs) in Wenzhou, China. At the site, PVDs were installed to a depth of 22?m from the ground surface with a spacing of 1.5?m in a triangular pattern. The preloading fill thickness was 6?m with a unit weight of approximately 18 kN/m³. After a total elapsed time of 310 days, approximately 3?m thick fill was removed. The measured preloading settlement was approximately 1.5?m. The measurements and analytical results indicated that the soil layer with PVD improvement reached almost 100% primary consolidation when part of the fill was removed. After partial unloading, the PVD-improved zone was in an over-consolidated state. After the runway was opened for traffic, a settlement increment of approximately 7?mm was monitored over a period of 11 months. Analysis indicated that the settlement was mainly due to the consolidation of soil layers below the PVD-improved zone and post-surcharge secondary consolidation of the PVD-improved zone. The values of the parameters related to PVD improvement were back-estimated from the field measurements. These findings can be used to guide the design of PVDs improvement along the east coast of China.     

Fabrication of Superjunction Trench Gate Power MOSFETs Using BSG‐Doped Deep Trench of p‐Pillar

In this paper, we propose a superjunction trench gate MOSFET (SJ TGMOSFET) fabricated through a simple p pillar forming process using deep trench and boron silicate glass doping process technology to reduce the process complexity. Throughout the various boron doping experiments, as well as the process simulations, we optimize the process conditions related with the p pillar depth, lateral boron doping concentration, and diffusion temperature. Compared with a conventional TGMOSFET, the potential of the SJ TGMOSFET is more uniformly distributed and widely spread in the bulk region of the n drift layer due to the trenched p‐pillar. The measured breakdown voltage of the SJ TGMOSFET is at least 28% more than that of a conventional device.     

Potentiometric detection of silver (I) ion based on carbon paste electrode modified with diazo-thiophenol-functionalized nanoporous silica gel

For the first time, triazene compound functionalized silica gel was incorporated into carbon paste electrode for the potentiometric detection of silver (I) ion. A novel diazo-thiophenol-functionalized silica gel (DTPSG) was synthesized, and the presence of DTPSG acted as not only a paste binder, but also a reactive material. The electrode with optimum composition, exhibited an excellent Nernstian response to Ag⁺ ion ranging from 1.0 × 10^? 6 to 1.0 × 10^? 1 M with a detection limit of 9.5 × 10^? 7 M and a slope of 60.4 ± 0.2 mV dec^? 1 over a wide pH range (4.0–9.0) with a fast response time (50 s) at 25 °C. The electrode also showed a long-time stability, high selectivity and reproducibility. The response mechanism of the proposed electrode was investigated by using AC impedance. Moreover, the electrode was successfully applied for the determination of silver ions in radiology films, and for potentiometric titration of the mixture solution of Cl^? and Br^? ions.     

Well-posedness and exact controllability of fourth-order Schrödinger equation with hinged boundary control and collocated observation

In this paper, we consider the well-posedness and exact controllability of a fourth-order multi-dimensional Schrödinger equation with hinged boundary by either moment or Dirichlet boundary control and collocated observation, respectively. It is shown that in both cases, the systems are well posed in the sense of D. Salamon, which implies that the systems are exactly controllable in some finite time interval if and only if its corresponding closed loop systems under the direct output proportional feedback are exponentially stable. This leads us to discuss further the exact controllability of the systems. In addition, the systems are consequently shown to be regular in the sense of G. Weiss as well, and the feedthrough operators are zero.     

高校网群建设与网络文化安全管理研究

高校网群建设与网络文化的快速发展,为传播信息、学习知识发挥了积极作用,同时也使意识形态领域多元、多样、多变的特点进一步凸现出来,给高校网络文化建设提出了新的课题。保定市顺应网络文化发展的大趋势,在高校中采取了一系列网群建设与网络文化安全管理的措施,并提出加强网络文化建设与安全管理的对策,构建了保定高校网群建设与网络文化安全防控体系。     

Homology Modeling Study of Bovine μ-Calpain Inhibitor-Binding Domains

The activated mammalian CAPN-structures, the CAPN/CAST complex in particular, have become an invaluable target model using the structure-based virtual screening of drug candidates from the discovery phase to development for over-activated CAPN linked to several diseases, such as post-ischemic injury and cataract formation. The effect of Ca²⁺-binding to the enzyme is thought to include activation, as well as the dissociation, aggregation, and autolysis of small regular subunits. Unfortunately, the Ca²⁺-activated enzyme tends to aggregate when provided as a divalent ion at the high-concentration required for the protease crystallization. This is also makes it very difficult to crystallize the whole-length enzyme itself, as well as the enzyme-inhibitor complex. Several parameters that influence CAPN activity have been investigated to determine its roles in Ca²⁺-modulation, autoproteolysis, phosphorylation, and intracellular distribution and inhibition by its endogenous inhibitor CAST. CAST binds and inhibits CAPN via its CAPN-inhibitor domains (four repeating domains 1–4; CAST1–4) when CAPN is activated by Ca²⁺-binding. An important key to understanding CAPN1 inhibition by CAST is to determine how CAST interacts at the molecular level with CAPN1 to inhibit its protease activity. In this study, a 3D structure model of a CAPN1 bound bovine CAST4 complex was built by comparative modeling based on the only known template structure of a rat CAPN2/CAST4 complex. The complex model suggests certain residues of bovine CAST4, notably, the TIPPKYQ motif sequence, and the structural elements of these residues, which are important for CAPN1 inhibition. In particular, as CAST4 docks near the flexible active site of CAPN1, conformational changes at the interaction site after binding could be directly related to CAST4 inhibitory activity. These functional interfaces can serve as a guide to the site-mutagenesis in research on bovine CAPN1 structure-function relationships for the design of small molecules inhibitors to prevent uncontrolled and unspecific degradation in the proteolysis of key protease substrates.     

冷成型焊接圆钢管径厚比限值合理取值的讨论

冷成型焊接圆钢管的径厚比过小会使钢管材料产生较强的冷作硬化效应,强度提高而延性、韧性与焊接性能下降。结合钢管标准的制定,对钢管径厚比的合理限值及径厚比与钢材伸长率的相关关系进行了研究与探讨,分析认为设定钢管中保有延伸率来确定其径厚比限值是较合理的方法。同时,对径厚比验证性试验数据进行的研究和分析表明,当冷成型圆管(Q345)的径厚比为15时,钢管材料强度提高而延性、韧性与焊接性能均有较大幅度下降。