多媒体查询语言及其评价准则

随着多媒体技术和多媒体相关应用的发展,对有效检索多媒体信息的要求越来越迫切.查询语言作为信息检索的有效工具,其研究也越来越受到关注.对现有的多媒体查询语言进行了全面的综述,将它们分为两类:专用语言和通用语言.尽管查询语言对多媒体信息系统提供有效的查询服务至关重要,但目前仍没有较好的多媒体查询语言评价准则.因此,针对多媒体查询语言的查询表达能力设计准则共16条,并根据这些准则对多媒体查询语言进行了评价.评价结果表明,这些语言能满足用户的基本查询要求,但在高级语义查询和不确定查询等方面还有欠缺.最后展望了多媒体查询语言的未来研究方向.     

同步语言Signal在综合航电系统建模仿真中的应用

为了辅助航空电子系统进行综合设计,提出了用Signal语言对新一代综合航电系统进行建模仿真和性能评估的方法。Signal语言是一种同步语言,它通过时钟推理机制来反映复杂系统的确定性、安全性、有界性等问题,能够直观地表示系统元素之间的约束关系及特性,通过构造同步实时评估模型来反映系统的实时性。基于ARINC653标准,对新一代模块化综合航电系统进行了建模仿真。     

基于融合百度指数的电商订单量组合预测研究

当前电商用户订单日志不断爆发式增加,日志行为数据亟需应用,在线用户订单量的快速动态预测成为研究的关键方向。为了提高订单量的预测精度,结合BP神经网络、基于Adaboost的BP神经网络和支持向量机的预测优点,提出一种基于融合网络搜索指数的组合预测模型,构建融合百度指数和电商用户订单信息的指标体系,并通过对比实验证明了网络搜索指数作为电商订单量组合预测模型影响因素的有效性。     

The Use of Distinctive Monoclonal Antibodies in FMD VLP- and P1-Based Blocking ELISA for the Seromonitoring of Vaccinated Swine

The serum neutralization (SN) test has been regarded as the “gold standard” for seroconversion following foot-and-mouth disease virus (FMDV) vaccination, although a high-level biosafety laboratory is necessary. ELISA is one alternative, and its format is constantly being improved. For instance, standard polyclonal antisera have been replaced by monoclonal antibodies (MAbs) for catching and detecting antibodies, and inactive viruses have been replaced by virus-like particles (VLPs). To the best of current knowledge, however, no researchers have evaluated the performances of different MAbs as tracers. In previous studies, we successfully identified site 1 and site 2 MAbs Q10E and P11A. In this study, following the established screening platform, the VLPs of putative escape mutants from sites 1 to 5 were expressed and used to demonstrate that S11B is a site 3 MAb. Additionally, the vulnerability of VLPs prompted us to assess another diagnostic antigen: unprocessed polyprotein P1. Therefore, we established and evaluated the performance of blocking ELISA (bELISA) systems based on VLPs and P1, pairing them with Q10E, P11A, S11B, and the non-neutralizing TSG MAb as tracers. The results indicated that the VLP paired with S11B demonstrated the highest correlation with the SN titers (R² = 0.8071, n = 63). Excluding weakly positive serum samples (SN = 16–32, n = 14), the sensitivity and specificity were 95.65% and 96.15% (kappa = 0.92), respectively. Additionally, the P1 pairing with Q10E also demonstrated a high correlation (R² = 0.768). We also discovered that these four antibodies had steric effects on one another to varying degrees, despite recognizing distinct antigenic sites. This finding indicated that MAbs as tracers could not accurately detect specific antibodies, possibly because MAbs are bulky compared to a protomeric unit. However, our results still provide convincing support for the application of two pairs of bELISA systems: VLP:S11B-HRP and P1:Q10E-HRP.     

NIR-Triggered Generation of Reactive Oxygen Species and Photodynamic Therapy Based on Mesoporous Silica-Coated LiYF4 Upconverting Nanoparticles

To date, the increase in reactive oxygen species (ROS) production for effectual photodynamic therapy (PDT) treatment still remains challenging. In this study, a facile and effective approach is utilized to coat mesoporous silica (mSiO₂) shell on the ligand-free upconversion nanoparticles (UCNPs) based on the LiYF₄ host material. Two kinds of mesoporous silica-coated UCNPs (UCNP@mSiO₂) that display green emission (doped with Ho³⁺) and red emission (doped with Er³⁺), respectively, were successfully synthesized and well characterized. Three photosensitizers (PSs), merocyanine 540 (MC 540), rose bengal (RB), and chlorin e6 (Ce6), with the function of absorption of green or red emission, were selected and loaded into the mSiO₂ shell of both UCNP@mSiO₂ nanomaterials. A comprehensive study for the three UCNP@mSiO₂/PS donor/acceptor pairs was performed to investigate the efficacy of fluorescence resonance energy transfer (FRET), ROS generation, and in vitro PDT using a MCF-7 cell line. ROS generation detection showed that as compared to the oleate-capped and ligand-free UCNP/PS pairs, the UCNP@mSiO₂/PS nanocarrier system demonstrated more pronounced ROS generation due to the UCNP@mSiO₂ nanoparticles in close vicinity to PS molecules and a higher loading capacity of the photosensitizer. As a result, the three LiYF₄ UCNP@mSiO₂/PS nanoplatforms displayed more prominent therapeutic efficacies in PDT by using in vitro cytotoxicity tests.     

LaO_x(OH)_y supported platinum catalysts for CO oxidation:Deactivation by formation of lanthanum carbonate

Platinum catalyst for CO oxidation has been studied for decades,due to its high activity and good stability.In this work,we prepared three different lantha num oxide or hydroxide supports(LaO_x(OH)_y),and deposited platinum(Pt) with 0.5 at% via an impregnation approach to synthesize Pt/LaO_x(OH)_y catalysts.However,we find that these catalysts perform a poor stability for the CO oxidation reaction.The fresh and used samples were comprehensively characterized by multiple techniques including power X-ray diffraction(XRD),X-ray absorption fine structure(XAFS),transmission electron microscopy(TEM),temperature-programmed reduction by carbon monoxide(CO-TPR) and thermogravimetric analysis(TGA),to demonstrate that the oxidized platinum atoms or clusters,without any component of Pt-Pt metallic bond,are highly dispersed on the surface of LaO_x(OH)_y.Furthermore,the as-formed lanthanum carbonate(La₂O₂CO₃) during the exposure to ambient circumstances or in the reaction atmosphere of CO+O₂,severely impair the reactivity of Pt/LaO_x(OH)_y.On the basis of the obtained experimental results,we have drawn a conclusion that the oxidized P_tO_x atoms or PtxOy clusters are the active species for CO oxidation,while the formation of lanthanum carbonate is the origin of deactivation on reactivity.     

昆明市某商业综合体地下空间疏散对策研究

大型商业综合体具有面积大、跨度大的特点,给防火工作带来了诸多困难,其火灾特点也具有复杂性与特殊性,主要表现在建筑空间大、内部纵横交错、火灾荷载大;同时人员密集、疏散难度大,极易造成群死群伤事故。因此,大型商业综合体的地下空间防火意义重大。文章以昆明市某商业中心为例,通过对地下空间的分析研究,针对其火灾危险性提出相应的措施,为大型商业综合体地下空间的防火措施及疏散对策提供参考。     

一种通用的继电保护数据库模型

首先分析了公共信息模型在描述保护信息方面的不足,然后以仿真培训系统为实际应用背景,提出了一种通用的继电保护数据库模型,它能够从保护装置的内部结构和外部特征2个方面完整地表达实际的保护装置。该数据库模型允许用户在保护装置级进行保护配置,支持用户通过自定义新型号的保护装置扩展装置模型,支持装置模型升级后保护配置的自动更新,从而大大提高了保护数据库的维护效率。使用该数据库模型实现的各种仿真培训系统现场运行良好、运行维护方便,证明了该模型的有效性。     

氨基脲衍生物的合成及其阴离子识别性能

以3-异氰酸丙基三乙氧基硅烷和2,4-二硝基苯肼为原料,制备了一种氨基脲衍生物阴离子受体R,通过1HNMR、13CNMR、FTIR和HRMS对其结构进行了表征.在二甲基亚砜(DMSO)体系,受体R通过UV-Vis吸收光谱的变化及溶液颜色的显著差别对F–、CH3COO–(Ac–)和CN–表现出良好的识别能力.此外,通过向...