Test bed for power amplifier behavioral characterization and modeling

Traditional test bed of power amplifier (PA) behavioral characterization and modeling based on vector signal analyzer (VSA) and often equipped with specialized software is both expensive and inflexible to modify to suit different scenarios. In this paper, a new test bed based on an oscilloscope or other general purpose data acquisition systems, which works as analog to digital converter (ADC) with a proper (radio frequency) RF bandwidth and maximum sampling rate, is proposed. The common impairments, e.g. transmitter IQ imbalances, channel delay, frequency offset, and carrier phase offset, are all well compensated. The accurately recovered envelopes of the PA’s input and output signals are used for a PA behavioral characterization and modeling. Furthermore, Relative envelope error (REE) parameter is proposed to evaluate the accuracy of envelope recovery. The experiment shows a very accurate RF signal envelope recovery, and a good performance of PA behavioral modeling.     

The influence of user-generated content on traveler behavior: An empirical investigation on the effects of e-word-of-mouth to hotel online bookings

The increasing use of web 2.0 applications has generated numerous online user reviews. Prior studies have revealed the influence of user-generated reviews on the sales of products such as CDs, books, and movies. However, the influence of online user-generated reviews in the tourism industry is still largely unknown both to tourism researchers and practitioners. To bridge this knowledge gap in tourism management, we conducted an empirical study to identify the impact of online user-generated reviews on business performance using data extracted from a major online travel agency in China. The empirical findings show that traveler reviews have a significant impact on online sales, with a 10 percent increase in traveler review ratings boosting online bookings by more than five percent. Our results highlight the importance of online user-generated reviews to business performance in tourism.     

In vitro antineoplastic activity of a novel lanthionine-containing peptide

It has been a long-term goal to discover peptides that can kill tumor cells while sparing normal tissues. Lan-7 is a novel, chemically stable peptide structurally related to somatostatin that contains a lanthionine bridge between the two cysteines in the peptide; TT-232 is a less stable analogue containing a disulfide bridge. The antitumor activity of Lan-7 was examined, relative to that of TT-232 and the clinically used analogue octreotide, against a panel of malignant human tumor cell lines and normal human hematopoietic precursors. Lan-7 was cytotoxic to all four tumor cell lines, with IC50 values ranging over a 2-fold range from 16 to 36 microM. The potency of Lan-7 was comparable to that of TT-232, and both of these agents were two to three times more potent than octreotide. At concentrations that were highly cytotoxic to tumor cells, Lan-7 produced no significant toxicity to normal human hematopoietic precursors. Lan-7 induced apoptosis in human ovarian carcinoma 2008 cells over the same concentration range at which it produced cytotoxicity, but it did so without activating G1, S, or G2 checkpoints, given that it produced no perturbation of cell cycle phase distribution. Cells engineered to overexpress P-glycoprotein were not more resistant to Lan-7 than isogeneic cells not expressing the mdr1 gene. These results make Lan-7 of interest as a potential cancer chemotherapeutic agent.     

A dual polarized aperture coupled circular patch antenna using a C-shaped coupling slot

The design and development of a dual linearly polarized aperture coupled circular microstrip patch antenna at C-band are presented. The antenna uses a novel configuration of symmetric and asymmetric coupling slots. Variations in isolation between orthogonal feedlines and antenna axial ratio with the position of coupling slots are studied and broadband isolation and axial ratio are achieved. The prototype antenna yields 7.6 dBi peak gain, 70/spl deg/ 3-dB beam width, 25 dB cross-polarization levels and an isolation better than 28 dB between the two ports. With an external quadrature hybrid coupler connected to the two orthogonal feedlines, the antenna yields 3-dB axial ratio bandwidth of more than 30% at 5.8 GHz.     

Validation of a French version of an informant-based questionnaire as a screening test for Alzheimer's disease

BACKGROUND: Development of informant-based screening tests for dementia is an emerging field. The reliability and validity of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), an instrument that screens for dementia in general, have been established. We conducted a study to validate a French version of the IQCODE as a screening test for Alzheimer's dementia in the elderly living in the community. METHOD: In the Canadian Study of Health and Aging, subjects were screened in their own homes using the modified Mini-Mental State Exam (3-MS). Those who screened positive, along with a sample of subjects who screened negative, were referred for a complete clinical examination. In Quebec, an informant was asked to complete the French version, IQCODE(F), at that time. Based on the final clinical diagnoses, performances of the IQCODE(F) and Mini-Mental State Examination (MMSE, converted from 3-MS) in screening for Alzheimer's disease were evaluated. RESULTS: Of the 237 subjects, the mean IQCODE (F) score was 3.4 (s.d. = 0.6), on a 5-point scale (1 = improvement in condition over the past 10 years, 5 = marked deterioration, 3 = no change). The mean MMSE score was 23.1 (s.d. = 4.5). The scores on the two scales were correlated (r = -0.44, P < 0.001). The IQCODE(F) scores were unrelated to education (r = -0.07, P > 0.3) in contrast to the MMSE scores (r = 0.28, P < 0.001). With respect to a diagnosis of probable Alzheimer's disease, the IQCODE(F) (cut-off point 3.6) had a sensitivity of 75% and a specificity of 95.6%. The sensitivity and specificity of the MMSE (cut-off point 23) were 70% and 82.3% respectively. CONCLUSION: The findings of the IQCODE(F) are consistent with those of the English version in correlation with the MMSE and apparent freedom from educational bias. The IQCODE is superior to the MMSE as a screening test for probable Alzheimer's disease in the elderly living in the community. It may be a useful addition to the screening tests already available, especially for the less well educated.