Indoor air quality in schools of a highly polluted south Mediterranean area

This study aimed at surveying lower secondary schools in southern Italy, in a highly polluted area. A community close to an industrial area and three villages in rural areas was investigated. Indoor temperature, relative humidity (RH), gaseous pollutants (CO₂ and NO₂), selected biological pollutants in indoor dust, and the indoor/outdoor mass concentration and elemental composition of PM_2.5 were ascertained. Temperature and RH were within, or close to, the comfort range, while CO₂ frequently exceeded the threshold of 1000 ppm, indicating inadequate air exchange rate. In all the classrooms, median NO₂ levels were above the WHO threshold value. Dermatophagoides p. allergen concentration was below the sensitizing threshold, while high endotoxin levels were detected in the classrooms, suggesting schools may produce significant risks of endotoxin exposure. Concentration and solubility of PM_2.5 elements were used to identify the sources of indoor particles. Indoor concentration of most elements was higher than outdoors. Resuspension was responsible for the indoor increase in soil components. For elements from industrial emission (Cd, Co, Ni, Pb, Sb, Tl, V), the indoor concentration depended on penetration from the outside. For these elements, differences in rural vs industrial concentrations were found, suggesting industrial sources may influence indoor air quality nearby schools.     

A Petri nets semantics for data flow networks

This work presents a truly concurrent operational semantics for nondeterministic data flow networks. We introduce a model, the df-process, which is a notion similar to that of non-sequential process for a Petri net: a df-process is defined as a mapping from an occurrence net K to a data flow net N, such that the places and the transitions of K are mapped onto the channels and the nodes of N. A df-process contains, by means of some labelling of the places, information on the value and the order in which data flow through the channels during a computation. Df-processes for a data flow network are characterized in an abstract way by a set of properties and in general a df-process corresponds to a set of computations of the network. We give a way to build the df-process corresponding to a computation incrementally at each event occurrence: a main result of the paper is that the incremental construction yields exactly the same set of df-processes as abstractly defined. We also show that df-processes are compositional. The model is intended to be used by distributed systems designers: it contains enough information to be a guideline for the designer and to be a base to develop dynamic checking tools. We outline how df-processes can be used in the design phase of a system.Research supported in part by Progetto Coordinato CNR ANATRA     

Methotrexate for psoriasis

Methotrexate is an effective antipsoriatic agent and has been widely used to treat severe psoriasis since the 1960s. It is especially useful in acute generalized pustular psoriasis, psoriatic erythroderma, psoriatic arthritis and for extensive chronic plaque psoriasis in patients who are inadequately controlled by topical therapy alone. It has not, however, been formally compared with other systemic treatments for severe psoriasis such as cyclosporin, retinoids or photochemotherapy with psoralen and UVA (PUVA), but in comparison with these other therapies it is inexpensive, with correct use, its safety profile is favourable. In summary, therefore, it can be used as a short-term option to gain control of unstable psoriasis such as pustular psoriasis or erythroderma before returning to other modes of treatment, or more often, as long-term maintenance treatment. The most important potential side-effect is acute myelosuppression, which is the cause of most of the rare deaths attributable to this therapy for psoriasis. Myelosuppression is more likely in the elderly, in patients with renal impairment and/or folate depletion, and with overdose or drug interactions. Long-term therapy carries with it a risk of liver fibrosis which is related to the dosage regimen employed, and is increased by exposure to other hepatic toxins, particularly alcohol. The correlation between the risk of development of liver fibrosis, cumulative lifetime dose and duration of treatment with methotrexate is not clear-cut, but may have been overstated in some studies.     

A dirichlet process elaboration diagnostic for binomial goodness of fit

Useful model checking tools can be constructed by measuring the distance between a prior distribution that concentrates most of its mass around a model of interest, and the resulting posterior distribution. In this paper we use this approach to construct a diagnostic measure for detecting lack of fit in discrete data, with special focus on binomial data. We begin by constructing a suitable probability model “around” the model of interest, via a Dirichlet Process elaboration. We derive the resulting diagnostic and show that, approximately, it is the sum of two terms: the first is the logarithm of the Bayes factor and the second is proportional to the Pearson chi-square statistics. We give details of a simulation algorithm for computing the diagnostic and illustrate its use in an application to biomedical data.     

Efficiency,effectiveness, and impacts assessment in the rail transport sector: a state‐of‐the‐art critical analysis of current research

This paper aims at being a comprehensive reference for stakeholders, policy makers, and scholars interested in analyzing the problem of efficiency, effectiveness, and impacts of rail transport systems in a sound empirical way, paying specific attention to passenger transport services. The paper combines different analytical frameworks (engineering, economics, impacts), systematic review techniques, and advanced mappings. Framing economic efficiency studies into a transport planning perspective permits to move from efficiency to effectiveness issues. In addition, including impacts offers a critical discussion of the existing empirical studies, relating them to the main methodological approaches used. This analysis can be useful for those interested in developing new techniques for the evaluation of this sector. The critical analysis developed in this paper provides a catalog of inputs, outputs, external factors, possible impacts to account for, data, and approaches, which allows us to identify areas in which new methodological developments, new approaches, are needed to address the relevant societal challenges of the rail transport sector.     

Verifying data secure flow in AUTOSAR models

This paper presents an approach for enhancing the design phase of AUTOSAR models when security annotations are required. The approach is based on information flow analysis and abstract interpretation. The analysis evaluates the correctness of the model by assessing if the flow of data is secure with respect to causal data dependencies within the model. To find these dependencies an exhaustive search through the model would be required. Abstract interpretation is used as a trade-off between the precision and complexity of the analysis. The approach also provides annotated models without oversizing the set of annotations.     

SRAM-Based FPGA Systems for Safety-Critical Applications：A Survey on Design Standards and Proposed Methodologies

As the ASIC design cost becomes affordable only for very large-scale productions, the FPGA technology is currently becoming the leading technology for those applications that require a small-scale prod...     

Preparation and characterization of polyurethane/silica aerogel nanocomposite materials

In this investigation, silica aerogel (SA)/Rigid Polyurethane (PUR) foam composites and silica aerogel/Polyurethane (PU) composites were prepared by dry mixing of granular and grinded silica aerogels with polyol part. They were then combined with diisocyanate part. Three different types of PUR foams and an elastomeric coating grade of PU were studied as well. Results show that thermal conductivity of foams did not decrease by adding silica aerogel. It even increased for some grades which is assumed to be due to the change in cell configuration of these foams. It was also found that sound insulation performance of these cellular composites did not improve significantly. Unlike foam composites, addition of silica aerogel into elastomeric PU improved its thermal and acoustic insulation properties. Because of the more promising properties of elastomeric PU composites, further examinations including measurements of compression strength and water contact angle of silica aerogel/PU composites were also taken. Final results showed a significant improvement in general properties of PU coatings by adding little amounts of silica aerogel (1–4 wt %). © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134, 44521.