Interpretation of CT studies: single-screen workstation versus film alternator

A prototype single-screen workstation with a 2,048 x 2,560-pixel high-brightness monitor, 0.11-second image display time, and simple ergonomic design was compared to a conventional horizontal film alternator in diagnostic interpretation of chest computed tomography (CT) studies. Four radiologists used either the workstation or film alternator in interpretation of studies obtained in 10 patients. A counterbalanced within-subject repeated measures experimental design was used. Response times were analyzed for both methods of interpretation. Grades of excellent, acceptable, and unacceptable were assigned by a blinded "grader" to reports of the radiologists. The average time needed for an interpretation at the workstation was 5.65 minutes. No interpretations were graded unacceptable. Retrospective power analysis showed that 16 observers rather than four would have been required to show that use of the workstation was faster than the alternator. With this 95% confidence interval, the workstation interpretation time is clinically equivalent to that with the alternator. These data show that this type of workstation has practical application in interpretation of CT, magnetic resonance imaging, and ultrasound studies.     

Controller-area-network bus control and monitor system for a radio astronomy interferometer

We describe the design and implementation of a controller-area-network bus (CANbus) monitor and control system for a millimeter wave interferometer. The Combined Array for Research in Millimeter-wave Astronomy (CARMA) is a 15-antenna connected-element interferometer for astronomical imaging, created by the merger of two university observatories. Its new control system relies on a central computer supervising a variety of subsystem computers, many of which control distributed intelligent nodes over CANbus. Subsystems are located in the control building and in individual antennas and communicate with the central computer via Ethernet. Each of the CAN modules has a very specific function, such as reading an antenna encoder or tuning an oscillator. Hardware for the modules was based on a core design including a commercial CANbus-enabled single-board computer and some standard circuitry for interfacing to peripherals. Hardware elements were added or changed as necessary for the specific module types. Similarly, a base set of embedded code was implemented for essential common functions such as CAN message handling and time keeping and extended to implement the required functionality for the different hardware. Using a standard CAN messaging protocol designed to fit the requirements of CARMA and a well-defined interface to the high-level software allowed separate development of high-level code and embedded code with minimal integration problems. Over 30 module types have been implemented and successfully deployed in CARMA, which is now delivering excellent new science data.     

Extrinsic optical-fiber ultrasound sensor using a thin polymer film as a low-finesse Fabry-Perot interferometer

Theoretical and experimental aspects of an extrinsic optical-fiber ultrasound sensor are described. The sensor is based on a thin transparent polymer film acting as a low-finesse Fabry-Perot cavity that is mounted at the end of a multimode optical fiber. Performance was found to be comparable with that of a piezoelectric polyvinylidene dinuoride-membrane (PVDP) hydrophone with a sensitivity of 61 mV/MPa, an acoustic noise floor of 2.3 KPa over a 25-MHz bandwidth, and a frequency response to 25 MHz. The wideband-sensitive response and design flexibility of the concept suggests that it may find application as an alternative to piezoelectric devices for the detection and measurement of ultrasound.     

Composition and biosynthesis of sterols in selected marine phytoplankton

Six species of phytoplankton,Pseudoisochrysis paradoxa, Isochrysis galbana, Monochrysis lutheri, Platymonas suecica, Thalassiosira fluviatilis and aChaetoceros species, were cultured in the laboratory and their sterol contents analyzed utilizing digitonin precipitation, thin layer and gas chromatography and gas chromatography-mass spectrometry. A total of 7 sterols were found in phytoplankton. The occurrence of these sterols, cholest-5-en-3β-ol, cholest-5,22-dien-3β-ol, 24-methylcholesta-5,24(28)-dien-3β-ol, 24-methylcholest-5-en-3β-ol, 24-methylcholesta-5,22-dien-3β-ol, 24-ethylcholest-5-en-3β-ol and 24-ethylcholest-5,22-dien-3β-ol, differed significantly among the various phytoplankton species. Cultures ofP. paradoxa biosynthesized both of the sterols found in this species when incubated in the presence of¹⁴C- or³H-mevalonic acid for 0.5–9 days. These sterols were cholesterol and 24-methylcholesta-5,22-dien-3β-ol. Since 5 of the sterols found in the phytoplankton commonly occur in mollusks which feed on phytoplankton, it is likely that at least some of the tissue sterols in mollusks are of dietary origin. Research trainee, HL 07295-02, National Heart, Lung and Blood Insitute.     

Sex pheromone of a conifer-feeding budworm,Choristoneura retiniana,Walsingham

Sex pheromone components collected from femaleChristoneura retiniana included 11-tetradecenyl acetates and alcohols. The major component wasE-11-tetradecenyl acetate (E11–14Ac) with a lesser amount ofZ isomer necessary to induce male response. A 928 ratio ofE,Z11–14 Ac appeared optimal. The alcohol component was present at about 10% of the total pheromone mixture, and traps baited with acetates plus alcohol surpassed unmated females in their degree of attractiveness. Chemical analysis indicated a 9:1 ratio of theE — Z isomers of 11-tetradecenyl alcohol (11–14ol) pheromone components, although bait formulations containing a predominance of either theE orZ isomers were equally successful in field bioassays. Based on male response to traps,E- andZ11–14Ac (928E — Z) are essential pheromone components for long-range sex attraction. The 11–14 ol enhanced attraction when added at 10% of the total pheromone blend.This paper reports the results of research only. Mention of a commercial product does not constitute a recommendation by the U.S. Department of Agriculture.     

Surface interaction of quaternary amines with hair

Surface analysis by X-ray photoelectron spectroscopy (XPS) has shown specific 1∶1 (ionic) interaction between cationic alkyl quaternary surfactant molecules and the anionic sulfonate groups present on the hair surface. The primary driving force for the adsorption of alkyl quaternary amine molecules to the surface of the hair from aqueous solution is the ionic interaction between quaternary groups and the surface SO₃ ⁻ on the hair. Cationic quaternary molecules incorporating ester and alcohol functionalities (ester quats) demonstrate a lower number of surface quaternary nitrogens per sulfonate group, indicating an altered surface interaction mechanism. For the ester quats, a combination of electrostatic interaction modes exists in addition to the ionic N⁺/SO₃ ⁻ interaction, specifically, H-bonding interactions of the −C−O, −C−OH, and −C(O)O− polar groups with SO₃ ⁻ and other polar groups on the hair. Surface coverage of the ester quat is not reduced despite the decrease in ionic interaction at the surface. Both types of molecules orient their alkyl tails toward the surface. Molecular dynamics modeling of the surfactant/hair surface interaction indicates higher adsorption energies due to increased dipolar interactions for ester quat molecules.     

The shape and stability of wall-bound and wall-edge-bound drops and bubbles

The behavior of wall-bound drops and bubbles is fundamental to many natural and industrial processes. Key characteristics of such capillary systems include interface shape and stability for a variety of gravity levels and orientations. Significant solutions are in hand for axisymmetric pendent drops for a variety of uniform boundary conditions along the contact line with gravity acting normal to a planar wall. The special case of a wall-bound drop or bubble that is also pinned at an edge (i.e. a ‘wall-edge-bound’ drop) is considered here where numerical solutions are obtained for interface shape and stability as functions of drop volume, contact angle, fluid properties, and uniform gravity vector. For a semi-infinite zero-thickness planar wall (plate), a critical contact angle is identified below which wall-edge-bound drops are always stable. The critical contact angle is computed as a function of the gravity vector. The numerical procedure, which makes no account for contact angle hysteresis, predicts that such wall-edge-bound drops are unconditionally unstable for any gravity field with a component that is tangent to the wall while inwardly normal to the edge. Select experiments are conducted that support the conclusions drawn from the numerical results.     

UAS Flight Simulation with Hardware-in-the-loop Testing and Vision Generation

UAS flight simulation for research and development is a difficult problem because each airframe requires accurate physical models, control systems, an organized method of testing new control systems, virtual cameras for vision-based control, and methods of testing new control in the transition from simulation to flight tests. In an environment where researchers are temporary, such as a university, a standard research and development platform with these properties expedites prototyping and prevents code loss when an employee leaves. We develop a research simulation which conforms to all of these properties inside a Matlab environment. A series of mex functions provide connections to the autopilot for hardware-in-the-loop testing, graphical interfaces, and vision processing. The option to write C mex functions offers a seamless method of porting code to embedded systems, minimizing coding errors. We demonstrate fast prototyping by showing flight test data where the simulation provided virtual vision data to avoid virtual obstacles.     

Statistical process monitoring approach for high-density point clouds

Statistical process control (SPC) methods have been extensively applied to monitor the quality performance of manufacturing processes to quickly detect and correct out-of-control conditions. As sensor and measurement technologies advance, there is a continual need to adapt and refine SPC methods to effectively and efficiently use these new data-sets. One of the most state-of-the-art dimensional measurement technologies currently being implemented in industry is the 3D laser scanner, which rapidly provides millions of data points to represent an entire manufactured part’s surface. Consequently, this data has a great potential to detect unexpected faults, i.e., faults that are not captured by measuring a small number of predefined dimensions. However, in order for this potential to be realized, SPC methods capable of handling these large data-sets need to be developed. This paper presents an approach to performing SPC using point clouds obtained through a 3D laser scanner. The proposed approach transforms high-dimensional point clouds into linear profiles through the use of Q–Q plots, which can be monitored by well established profile monitoring techniques. In this paper point clouds are simulated to determine the performance of the proposed approach under varying fault scenarios. In addition, experimental studies were performed to determine the effectiveness of the proposed approach using actual point cloud data. The results of these experiments show that the proposed approach can significantly improve the monitoring capabilities for manufacturing parts that are characterized by complex surface geometries.     

Cooperative Target-capturing with Incomplete Target Information

This paper presents a distributed target-centric formation control strategy for multiple unmanned aerial vehicles (UAVs) in the presence of target motion uncertainty. The formation is maintained around a target using a combination of a consensus protocol and a sliding mode control law. Consensus helps in distributing the target information which is available only to a subset of vehicles. Sliding mode control compensates for the uncertainty in the target information. Hence, collectively the combined strategy enforces each of the vehicles to maintain its respective position in the formation. We show that if at least one vehicle in a group has target information with some uncertainty and the corresponding communication graph is connected, then a target-centric formation can be maintained. The performance of the proposed strategy is illustrated through simulations.