中药知母有效组分——知母皂甙元“滋阴”作用的研究

本工作以~(123)I-心得静结合分析法及环核苷酸RIA法观察了知母中提取得到的知母皂甙元对甲亢模型(模拟“阴虚”)βAR-cAMP系统的作和,结果表现,知母皂甙元明显降低甲亢小鼠脑β受体的RT值,显著降低甲亢小鼠β受体-cAMP系统的反应性,重现了知母水煎剂的下调作用。体外竞争抑制实验表明,知母皂甙元和知母皂甙元半琥珀酸都不能抑制~(125)I-心得静与β受体的结合。     

Acoustic emission from gas-filled coal under triaxial compression

Acoustic emission (AE) experiments have been performed on gas-saturated coal specimens under conventional triaxial compression. The AE characteristics were investigated for a methane gas flow through the coal specimen. One AE parameter, AE count, when normalized by the total count number was used to represent the damage evolution in the gassy coal. It is shown that this AE parameter is a reasonable indicator for damage occurring within the coal specimen since its envelope has almost the same shape as the complete stress–strain curve, except for a short time delay. In addition, the change in AE count is highly consistent with the change in coal permeability. Test results also show that methane containing coal emits a small number of AE events before entering the yield stage. AE activity gradually increases during the yield process up to the peak stress. The lowest permeability corresponds to the highest AE activity, implying failure will soon occur. An AE based constitutive model was constructed and the theoretical results agree well with those of experiments.     

Robust and efficient ridge-based palmprint matching

During the past decade, many efforts have been made to use palmprints as a biometric modality. However, most of the existing palmprint recognition systems are based on encoding and matching creases, which are not as reliable as ridges. This affects the use of palmprints in large-scale person identification applications where the biometric modality needs to be distinctive as well as insensitive to changes in age and skin conditions. Recently, several ridge-based palmprint matching algorithms have been proposed to fill the gap. Major contributions of these systems include reliable orientation field estimation in the presence of creases and the use of multiple features in matching, while the matching algorithms adopted in these systems simply follow the matching algorithms for fingerprints. However, palmprints differ from fingerprints in several aspects: 1) Palmprints are much larger and thus contain a large number of minutiae, 2) palms are more deformable than fingertips, and 3) the quality and discrimination power of different regions in palmprints vary significantly. As a result, these matchers are unable to appropriately handle the distortion and noise, despite heavy computational cost. Motivated by the matching strategies of human palmprint experts, we developed a novel palmprint recognition system. The main contributions are as follows: 1) Statistics of major features in palmprints are quantitatively studied, 2) a segment-based matching and fusion algorithm is proposed to deal with the skin distortion and the varying discrimination power of different palmprint regions, and 3) to reduce the computational complexity, an orientation field-based registration algorithm is designed for registering the palmprints into the same coordinate system before matching and a cascade filter is built to reject the nonmated gallery palmprints in early stage. The proposed matcher is tested by matching 840 query palmprints against a gallery set of 13,736 palmprints. Experimental results show that the proposed matcher outperforms the existing matchers a lot both in matching accuracy and speed.     

Identification of Breast Cancer Prognosis Markers via Integrative Analysis

In breast cancer research, it is of great interest to identify genomic markers associated with prognosis. Multiple gene profiling studies have been conducted for such a purpose. Genomic markers identified from the analysis of single datasets often do not have satisfactory reproducibility. Among the multiple possible reasons, the most important one is the small sample sizes of individual studies. A cost-effective solution is to pool data from multiple comparable studies and conduct integrative analysis. In this study, we collect four breast cancer prognosis studies with gene expression measurements. We describe the relationship between prognosis and gene expressions using the accelerated failure time (AFT) models. We adopt a 2-norm group bridge penalization approach for marker identification. This integrative analysis approach can effectively identify markers with consistent effects across multiple datasets and naturally accommodate the heterogeneity among studies. Statistical and simulation studies demonstrate satisfactory performance of this approach. Breast cancer prognosis markers identified using this approach have sound biological implications and satisfactory prediction performance.     

Monitoring the Synthesis and Composition Analysis of Microsilica Encapsulated Acetylacetonatocarbonyl TriphenylphosphinerhodiumCatalyst by Inductively Coupled Plasma (ICP) Techniques

A novel technique to monitor the synthesis process of encapsulated acetylacetonatocarbonyl triphenylphosphinerhodium within a microsilica nanoshell has been studied using inductively coupled plasma (ICP) techniques. Nanospheres sized around 50-100 nm were obtained and ICP was used to quantify the exact composition of rhodium, phosphorous, and silicon with differing digestion solvents. In addition, ICP was used to detect rhodium and phosphorous in the nano core-shell catalysts as a quality control procedure     

基于Intel 815E芯片组的PCI-104 CPU模块设计

本文描述了基于Intel815E芯片组的PCl-104 CPU模块设计,对系统结构、总线拓扑、系统存储器以及外设等在设计过程中的注意事项作了阐述.     

喷射沉积柱坯的生长模型

根据现有喷射沉积设备的喷射几何关系推导了柱状沉积坯生长的数学模型,并利用该模型对沉积器的临界下降速度进行了初步估算。     

小波分析在三维地形数据简化中的应用研究

研究了小波分析在三维地形数据简化中的应用。在分析了小波多分辨率分析理论的基础上,重点探讨了小波多分辨率分析理论在三维地形简化中的应用,提出了实现三维地形数据简化的一种新的方法。     

A New Grade Carbon Black Produced by Thermal Plasma Process

This paper presents a new route about producing carbon black,by wich the natural gas cracking is carried out in the absence of oxygen thanks to an electric energy supply externally given by a plasma jet.The carbon black produced by this process has a narrow size distribution and a small average diameter of 38nm as well as a highly branched aggregate.The higher DBP value of 1.40ml/g shows it should be a high structure carbon black.The FTIR spectra shows that there are lots of aromatic c-c bonds and a large amount of nitrogen-coutaining functional groups on the carbon blacks surface,such as-NH,-CN as we3ll as -CH,-OH,-COOH groups.     

元数学对计算机科学的启示

文章提出了元数学对计算机科学的几点启示,这几个方面分别是传统程序设计的概念、机制、要素,数据库技术中的数据模型和函数依赖,面向对象分析和设计方法。文中一方面分析了元数学所提供的理论基础,另一方面说明了在应用方面是如何体现这些理论基础的,并提出了在计算机技术领域中应从数学基础问题、数理逻辑等的相关理论着手寻找突破的思想。