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31.
Q Hu M Trevisan Y Xu W Dong SA Berger SD Lyman MD Minden 《Canadian Metallurgical Quarterly》1995,95(6):2530-2538
The growth of human leukemic cells in culture and in vivo is dependent upon the presence of hematopoietic growth factors. Most populations of human leukemic acute myeloblastic leukemia (AML) cells express c-Kit on their surface and respond to Kit ligand (KL) in culture. To determine if this interaction was of potential significance in vivo we used a mouse model system. 32D cells, a murine IL-3-dependent myeloid cell line, were rendered KL responsive by transfection of the murine c-Kit. After injection of 32D or 32D-Kit cells into syngeneic hosts, animals bearing 32D-Kit cells, but not 32D cells, became moribund and were killed. These animals had circulating leukemic blast cells, infiltration of bone marrow, spleen, brain, liver, lung, and kidney. Cells recovered from some of the animals continued to be dependent upon IL-3 or KL for growth while in other cases the cells were factor independent. This model illustrates that the constitutive expression of c-Kit enhances the leukemic potential of 32D cells. The model will be useful for studying the progression of leukemia in vivo and testing whether interruption of the interaction of Kit and KL can affect the growth of leukemic cells. 相似文献
32.
Kwang Soo Lee In Soo Park & Dong Sun Lee 《International Journal of Food Science & Technology》1996,31(1):7-13
The aim of this study was to design a modified atmosphere package for a mixed vegetable salad consisting of 75 g of cut carrot, 55 g of cut cucumber, 20 g of sliced garlic and 50 g of whole green pepper. Respiration data of all the components were combined with film permeability data to predict package atmospheres and design optimal packages for experimental testing for improved shelf-life of the produce. The optimal package avoided minimum O2 and maximum CO2 tolerance limits, and chilling injury temperatures for any component. A pouch form package made of 27 mm low density polyethylene developed a modified atmosphere of 2.0–2.1% O2 and 5.5–5.7% CO2 , which was beneficial for all components and provided better quality retention than other test packages. 相似文献
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During the 1997 winter season, shipborne polarimetric backscatter measurements of Great Lakes (freshwater) ice types using the Jet Propulsion Laboratory C-band scatterometer, together with surface-based ice physical characterization measurements and environmental parameters, were acquired concurrently with Earth Resource Satellite 2 (ERS-2) and RADARSAT Synthetic Aperture Radar (SAR) data. This polarimetric data set, composed of over 20 variations of different ice types measured at incident angles from 0° to 60° for all polarizations, was processed to radar cross-section to establish a library of signatures (look-up table) for different ice types. The library is used in the computer classification of calibrated satellite SAR data. Computer analysis of ERS-2 and RADARSAT ScanSAR images of Great Lakes ice cover using a supervised classification technique indicates that different ice types in the ice cover can be identified and mapped, and that wind speed and direction can have an influence on the classification of water as ice based on single frequency, single polarization data. Once satellite SAR data are classified into ice types, the ice map provides important and necessary input for environmental protection and management, ice control and ice breaking operations, and ice forecasting and modeling efforts. 相似文献
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介绍3J特级防火卷帘的各种重要功能特点,讨论其实用性与易用性以及推广该产品的必要性与可行性。 相似文献
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目的探讨膝下动脉的球囊成形术在治疗糖尿病缺血性下肢病变中的价值。方法对53例糖尿病合并缺血性下肢病变患者64侧缺血性下肢进行膝下动脉Deep球囊扩张成形术。对比患者手术前后临床症状的改变及足部溃疡的变化。结果53例患者共119支动脉分支接受PTA治疗,50例患者的101个分支成功地开通,技术成功率为84.9%,所有50例患者的临床症状均明显缓解,足部溃疡均变小,无需截肢。结论膝下动脉的球囊成形术是治疗缺血性糖尿病下肢病变安全有效的微创手段 相似文献
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将富于变化的女红工艺与单调的针织服装相结合,会使针织服装由平淡变为丰富,由呆板变为活泼。文章论述了在针织服装中运用女红图案、色彩、材料、针法的原理。 相似文献
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