混合脱水系统爆炸的原因及预防措施

根据氯碱厂生产实际,详细分析了混合脱水系统爆炸的原因,并提出了预防措 施。     

对流扩散方程的离散技术及数值实验

本文研究了对流扩散方程的离散技术,并进行了大量数值实验。研究表明,scharfetter—Gummel的广义形式可以良好地消除内部的非物理振荡,且对边界层生成振荡的传播有抑制作用,但不能有效地消除边界层振荡。     

Mechanisms of resistance in a human cell line exposed to sequential topoisomerase poisoning

Camptothecins are a new class of anticancer drugs that target DNA topoisomerase I; current efforts are directed toward elucidating optimal combinations of these drugs with other antineoplastic agents. A rationale for the use of sequential therapy involving the combination of camptothecins with topoisomerase II-targeting drugs, such as etoposide, has arisen from observations of increased topoisomerase II protein levels in cell lines resistant to camptothecin. In an effort to understand potential mechanisms of resistance to this strategy, we developed a U-937 cell subline, denoted RERC, that is capable of surviving exposure to sequential topoisomerase poisoning. The RERC cells are 200-fold resistant to camptothecin, 8-fold resistant to etoposide, and 10-fold hypersensitive to cisplatin compared to the parental U-937 cells. Biochemical analyses indicate that the resistant phenotype involves alterations in both topoisomerase I and topoisomerase IIalpha. Topoisomerase I catalytic activity in the resistant cells is similar to that of the parental line but is resistant to camptothecin. Moreover, the resistant cells express a single mRNA species of topoisomerase I that codes for a mutation in codon 533. In addition, topoisomerase IIalpha protein levels are decreased 10-fold in the resistant line, coincident with a two-fold decrease in the expression of topoisomerase IIalpha mRNA. Collectively, these results indicate that resistance to sequential topoisomerase poisoning may involve a reduction in total cellular topoisomerase activity.     

稀土树脂相分光光度法研究

在HCl—KCl(pH0.5)介质中,稀土—三溴偶氮胂二元络合物能较好地被阴离子交换树脂吸附。RE_2O_8在0～8μg/25ml范围内符合比尔定律,以双波长等吸收点法(测量波长λ_1=650nm,参比波长λ_2=740nm)扣除树脂背景影响,应用于稀土矿中稀土总量测定,结果令人满意。     

一种高精度大位移电容式位移测量系统

介绍一种新型的电容式位移测量系统，其测量范围为０～２５ｍｍ，线性度优于１／１０００，分辨率为０．１μｍ。文中详细分析了该系统的工作原理，特点及主要误差因素，给出了部分实验数据。     

快速锁相频率合成器

介绍了锁相合成技术，对提高可编程分频器速度作了分析，估算了跳频时间，提出了进一步缩短跳频时间的措施。     

ISDN PBX及X.25网关的管理

本文介绍了ＩＳＤＮ用户一网络接口的管理模型，分析了ＰＢＸ、Ｘ．２５网关的管理功能，对协议测试，管理通信进行了研究并提出模型及实现原则。     

全双极WTA模型的改进及其实现

提出了一种相似度的新定义，使双极ＷＡＴ模型的实现更加简洁明了。增加一个阈值使系统能判别非存储模式或因其信息量过低而无法鉴定的输入模式，阈值的大小与要求的容错能力有关。双极相似度及阈值通过光学方法实现。阈值的光学实现使系统仍具有照明不变性。通过电路实现取及ＷＴＡ网络的迭代运算。