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81.
Novel biomarkers of nasopharyngeal carcinoma metastasis risk identified by reverse phase protein array based tumor profiling with consideration of plasma Epstein–Barr virus DNA load 下载免费PDF全文
82.
Frank R. Stermitz Dale R. Gardner Francois J. Odendaal Paul R. Ehrlich 《Journal of chemical ecology》1986,12(6):1459-1468
Iridoid glycosides were found to be sequestered by natural populations ofEuphydryas anicia after ingestion from the host plantsBesseya alpina, B. plantaginea, andCastilleja integra. Both major iridoids ofB. alpina, cataipol and aucubin, were found in butterfly populations where this was the only host plant. The catalpol-aucubin ratio was higher in the butterflies than in the host plant. AnE. anicia population which uses bothB. plantaginea andC. integra as host plants was found to sequester cataipol as well as another iridoid, macfadienoside. Macfadienoside was the major iridoid ofC. integra, while catalpol esters were the major iridoids ofB. plantaginea. Although it was a major sequestered iridoid, catalpol was a minor constituent in both host plants. The macfadienoside-catalpol ratio in the butterflies from this population was highly variable, and there appeared to be both sex and individual variation in host plant and/or iridoid glucoside utilization byE. anicia. Although other iridoids were present in the host plants, none was sequestered in more than trace amounts.This work was supported by grant CHE-8213714 to FRS, in part by grant DEB-06961 to PRE from the National Science Foundation, and a grant from the Koret Foundation of San Francisco to PRE. Paper 5 in the series Chemistry of the Scrophulariaceae. Paper 4: Roby, M.R. and Stermitz, F.R. 1984.J. Nat. Prod. 47:854–857. 相似文献
83.
Eva Monroy Fabien Guillot Sylvain Leconte Laurent Nevou Laetitia Doyennette Maria Tchernycheva Francois H. Julien Esther Baumann Fabrizio R. Giorgetta Daniel Hofstetter 《Journal of Materials Science: Materials in Electronics》2008,19(8-9):821-827
In this work, we summarize the latest progress in intersubband devices based on GaN/AlN nanostructures for operation in the near-infrared. We first discuss the growth and characterization of ultra-thin GaN/AlN quantum well and quantum dot superlattices by plasma-assisted molecular-beam epitaxy. Then, we present the performance of nitride-based infrared photodetectors and electro-optical modulators operating at 1.55 μm. Finally, we discuss the progress towards intersubband light emitters, including the first experimental observation of intersubband photoluminescence in nitride nanostructures. 相似文献
84.
85.
Destrempes F Mignotte M Angers JF 《IEEE transactions on pattern analysis and machine intelligence》2007,29(9):1603-1615
In this paper, we present a new model for deformations of shapes. A pseudo-likelihood is based on the statistical distribution of the gradient vector field of the gray level. The prior distribution is based on the Probabilistic Principal Component Analysis (PPCA). We also propose a new model based on mixtures of PPCA that is useful in the case of greater variability in the shape. A criterion of global or local object specificity based on a preliminary color segmentation of the image, is included into the model. The localization of a shape in an image is then viewed as minimizing the corresponding Gibbs field. We use the Exploration/Selection (E/S) stochastic algorithm in order to find the optimal deformation. This yields a new unsupervised statistical method for localization of shapes. In order to estimate the statistical parameters for the gradient vector field of the gray level, we use an Iterative Conditional Estimation (ICE) procedure. The color segmentation of the image can be computed with an Exploration/Selection/Estimation (ESE) procedure. 相似文献
86.
There is interest as to whether the electromagnetic fields used in mobile radiotelephony might affect biological processes. Other weak fields such as gravity intervene in a number of physical and biological processes. Under appropriate in vitro conditions, the macroscopic self-organization of microtubules, a major cellular component, is triggered by gravity. We wished to investigate whether self-organization might also be affected by radiotelephone electromagnetic fields. Detecting a possible effect requires removing the obscuring effects triggered by gravity. A simple manner of doing this is by rotating the sample about the horizontal. However, if the external field does not also rotate with the sample, its possible effect might also be averaged down by rotation. Here, we describe an apparatus in which both the sample and an applied radiofrequency electromagnetic field (1.8 GHz) are stationary with respect to one another while undergoing horizontal rotation. The electromagnetic field profile within the apparatus has been measured and the apparatus tested by reproducing the in vitro behavior of microtubule preparations under conditions of weightlessness. Specific adsorption rates of electromagnetic energy within a sample are measured from the initial temperature rise the incident field causes. The apparatus can be readily adapted to expose samples to various other external fields and factors under conditions of weightlessness. 相似文献
87.
Patard Louis; Stoven Veronique; Gharib Bouchra; Bontems Francois; Lallemand Jean-Yves; De Reggi Max 《Protein engineering, design & selection : PEDS》1996,9(11):949-957
Human lithostathine is a 144-residue protein, expressed in variousorgans and pathologies. Several biological functions have beenproposed for this protein. Among others, inhibition of nucleationand growth of CaCO3 crystals in the pancreas and bacterial aggregationhas retained attention, because lithostathine presents highsequence similarities with calcium-dependent (or C-type) lectins.To study its structure-function relationship and compare itwith that of C-type lectins, we have built a model for lithostathine.This model is derived from the only two C-type lectins of knownstructures: rat mannose binding protein and human E-selectin.An original strategy, inspired by that proposed by Havel andSnow, was designed for model building. We have undertaken NMRstudies on the natural protein. Although complete structuredetermination has not yet been achieved, the NMR studies didconfirm the main characteristics of the model. From analysisof the proposed model, we concluded that lithostathine is notexpected to present sugar- or calcium-binding properties. Therefore,the mechanisms of bacterial aggregation and inhibition of CaCO3nucleation and growth have not yet been elucidated. 相似文献
88.
A. Littner M. Francois B. Malaman J. Steinmetz M. Vilasi E. Elkaim 《Intermetallics》2003,11(11-12):1223
Efforts to improve the high temperature behavior of MoSi2 in oxidizing environments led to the investigation of the Mo–Ru–Si phase diagram. The isothermal section at 1673 K was determined by X-ray diffraction, optical and scanning electron microscopies and EPMA. Five new silicides were identified and their crystallographic structure was characterized using conventional and synchrotron X-ray as well as neutron powder diffraction. Mo15Ru35Si50, denoted α-phase, is of FeSi-type structure, space group P213, a=4.7535 (5) Å, Dx=7.90 g. cm−3, Bragg R=7.13. Mo60Ru30Si10 is the ordered extension of the Mo70Ru30 σ-phase with space group P42/mnm, a=9.45940(8) Å, c=4.94273(5) Å, Dx=6.14 g. cm−3, Bragg R=5.75. 相似文献
89.
Nielsen Guillaume Coudert Lucie Janin Amelie Blais Jean Francois Mercier Guy 《Mine Water and the Environment》2019,38(1):104-118
Mine Water and the Environment - Acid mine drainage (AMD) is a major environmental challenge for the mining industry in northern climates. Laboratory-scale experiments were conducted to test... 相似文献
90.
Fate of N-nitrosodimethylamine, trihalomethane and haloacetic acid precursors in tertiary treatment including biofiltration 总被引:1,自引:0,他引:1
The presence of disinfection by-products (DBPs) such as trihalomethanes (THMs), haloacetic acids (HAAs) and N-nitrosamines in water is of great concern due to their adverse effects on human health. In this work, the removal of N-nitrosodimethylamine (NDMA), total THM and five HAA precursors from secondary effluent by biological activated carbon (BAC) is investigated at full and pilot scale. In the pilot plant two filter media, sand and granular activated carbon, are tested. In addition, we evaluate the influence of ozonation prior to BAC filtration on its performance. Among the bulk of NDMA precursors, the fate of four pharmaceuticals containing a dimethylamino moiety in the chemical structure are individually investigated. Both NDMA formation potential and each of the studied pharmaceuticals are dramatically reduced by the BAC even in the absence of main ozonation prior to the filtration. The low removal of NDMA precursors at the sand filtration in comparison to the removal of NDMA precursors at the BAC suggests that adsorption may play an important role on the removal of NDMA precursors by BAC. Contrary, the precursors for THM and HAA formation are reduced in both sand filtration and BAC indicating that the precursors for the formation of these DBPs are to some extent biodegradable. 相似文献