Effects of a K+ATP channel opener, lemakalim, on systemic, coronary and regional vascular dynamics in conscious dogs: comparison with nifedipine, adenosine, nitroglycerin and acetylcholine

The systemic, coronary and regional vascular responses to the K+ATP channel opener lemakalim were compared to other potent vasodilators (i.e., nifedipine, adenosine, nitroglycerin and acetylcholine). Experiments were performed in 12 conscious dogs 2 to 4 weeks after implantation of aortic catheters and flow probes on the ascending aorta, left circumflex coronary, celiac, mesenteric, renal and iliac arteries, and solid-state miniature pressure gauges in the left ventricular cavity. Dose-response curves induced by bolus injection (i.v.) were examined. For doses that reduced total peripheral resistance by 22%, lemakalim reduced celiac (-28 +/- 2%), mesenteric (-24 +/- 3%), renal (-17 +/- 3%) and iliac (-18 +/- 3%) vascular resistances (i.e., by amounts similar to those observed with the other vasodilators, except for adenosine, which increased renal resistance). At these doses, lemakalim induced a greater decrease (-52 +/- 3%) (P < .05) in coronary resistance, as compared with nifedipine (-35 +/- 3%), adenosine (-38 +/- 3%), nitroglycerin (-25 +/- 2%) and acetylcholine (-32 +/- 3%). However, when near maximal vasodilation was elicited, adenosine elicited the greatest (P < .05) decrease in coronary resistance (-81 +/- 1%), as compared with lemakalim (-74 +/- 2%), nifedipine (-67 +/- 2%), nitroglycerin (-63 +/- 2%) and acetylcholine (-72 +/- 1%). Both the time to maximal increases in regional blood flow and the time for recovery in all vascular beds were significantly prolonged for lemakalim compared with the other vasodilators. Thus, the K+ATP channel opener lemakalim dilates the coronary bed out of proportion to other vascular beds, is relatively more potent at lower doses than other vasodilators and exhibits a delayed and more prolonged action in all regional vascular beds.     

氟塑料—石墨板式换热器在高温强腐蚀换热工况中的应用

通过氟塑料－石墨板式换热器在化纤生产中高温强腐蚀换热工况中的实际应用，并与常规换热器的使用情况的对比分析，阐述了这种新型换热设备的特点。     

GaN and AlGaN high-voltage rectifiers grown by metal-organic chemical-vapor deposition

In this paper, we report the study of the electrical characteristics of GaN and AlGaN vertical p-i-n junctions and Schottky rectifiers grown on both sapphire and SiC substrates by metal-organic chemical-vapor deposition. For GaN p-i-n rectifiers grown on SiC with a relatively thin “i” region of 2 μm, a breakdown voltage over 400 V, and forward voltage as low as 4.5 V at 100 A/cm² are exhibited for a 60-μm-diameter device. A GaN Schottky diode with a 2-μm-thick undoped layer exhibits a blocking voltage in excess of ∼230 V at a reverse-leakage current density below 1 mA/cm², and a forward-voltage drop of 3.5 V at a current density of 100 A/cm². It has been found that with the same device structure and process approach, the leakage current of a device grown on a SiC substrate is much lower than a device grown on a sapphire substrate. The use of Mg ion implantation for p-guard rings as planar-edge terminations in mesageometry GaN Schottky rectifiers has also been studied.     

A study on the growth curve of and maximum profit from layer-type cockerel chicks

Attacks by adult stages of the soft tick Argas (Argas) neghmei (Acari: Argasidae) on inhabitants of the High Andean plateau of Argentina are reported. This is the first local report of this species, which was previously found in the north of Chile. Taxonomic differences between A. (A.) neghmei and other neotropical and exotic species of the genus are underlined. The status of the knowledge about the Argentine argasid fauna is briefly described.     

R-Calculus for ELP:An Operational Approach to Knowledge Base Maintenance

Sme concepts used in knowledge base maintenace,such as sequence,new law,user‘s rejection and reconstructions of a knowledge base,are first introduced,and then a framework for extended logic programming(ELP)is given,where an extended logic program is equivalent to a knowledge base.A transition system called R-calculus for ELP is provided.For a given knowledge base and a user‘s rejection,the R-calculus for ELP will deduce best revisions of the base.The soundness and the completeness of the R-calculus for ELP are proved,and the R-calculus for ELP is implemented in Prolog.In addition,the research is compared with other relevant work.     

心电地图仪中工频干扰的一种滤除方法

在心电地图仪中记录到的体表心电信号往往由于电磁的影响而引进工频干扰．基于体表心电信号中工频干扰的特点，作者提出了一种滤除工频干扰的方法，即就单独—胸导联信号通过提高频谱的分辨率来估计工频干扰的频率；基于最小均方误差准则来估计各导联信号中工频干扰的幅度和相位。文中还给出了该算法的流程图和滤波性能分析。模拟结果表明了该算法的有效性。应用该算法对心电地图仪中的工频干扰进行对消，取得了满意的结果。     

对分布式数据库发展方向的分析

本文对分布式数据库的设计方法、分割与分配技术作了一些探讨，并就分布式数据库的发展方向进行了初步分析。     

废钢铁代用品

优质钢材的冶炼和高水平操作指标的获得需要优良的原料作保证。直接还原铁，碳化铁和脱碳粒铁作为废钢铁代用品，已显示出其价格和品质上的优越性，并弥补了废铁数量的不足，但因其各有自身的特点，故研究其理化性质和使用性能，将为大规模生产和使用创造必要的条件。     

人工神经网络预测热油环道启动压力

高含蜡原油管道停输后的再启动问题非常复杂。它涉及因素多，问题的非线性很强。而有足够多神经元的S型三层神经网络理论上可逼近任意有理函数。文章采用误差反向传播网络预测环道实验装置中的启动压力，得到了较好结果。     

大坝安全监控专家系统中的知识处理

在介绍产生式规则及其数学模型的基础上，论述了用成熟的关系数据库 技术来表示和存储产生式规则表示的专家知识的方法，较好地解决了知识的存储和管理问题 。同时，利用关系数据库中实体间的关系，很容易将分散存储的规则元素组合成规则供推理 时使用。在分析了大坝安全监控专家系统知识特点的基础上举例说明了用关系数据库表 示产生式规则的具体方法。