Persistence of Muller's ducts in the male. A family observation (author's transl)

The authors report two cases (in brothers) of the persistence of Muller's ducts (uterus and uterine tubes), whilst both individuals led a normal though infertile sex life. They presented with a bilateral inguinal hernia and a cryptorchidism. The precise diagnosis was made at surgery in the first, whilst the family history led to the diagnosis in the second. Both underwent bilateral orchidopexy, and hysterectomy with excision of the uterine tubes. The caryotypes were normal. Of anatomical interest was the fact that both had vas deferens included within the uterine wall but the there was no continuity between the epididymes and the testes. The latter contained seminiferous ducts, Sertoli cells and spermatogonia but no spermatocyte nor spermatozoa. On the basis of these cases, the authors emphasise their demonstrative nature: the presence of testes resulted by the secretion of testosterone in the induction of normal external genitalia whilst the absence of factor inhibiting Mullers ducts (or tissue resistance to this factor) resulted in the development of the uterine tubes and uterus.     

Does solitary plasmacytoma still exist? Value of MRI of the spine

In order to differentiate benign from malignant pulmonary masses by means of observing blood flow signal, with coloured Doppler sonography, the authors examined 67 in-patients who had been found having masses in the lungs by X-ray or CT. For comparison 43 benign cases showing blood signals in the lung was also examined. The results showed that the blood flow signals of all lung cancers were of relatively low blood flow resistance or arteriovenous shunting, while those of benign lesions were of high blood flow resistance. The pulsatility index in lung cancer was 1.02 +/- 0.30, the restance index was 0.52 +/- 0.13, the peak systolic velocity was 0.19 +/- 0.11 m/s, the end diastolic velocity was 0.06 +/- 0.02 m/s. The pulsatility index in benign pulmonary lesions was 1.53 +/- 0.30, the resitance index was 0.86 +/- 0.05, the peak systolic velocity was 0.28 +/- 0.05 m/s and the end diastolic velocity was 0.04 +/- 0.01 m/s. There were significant differences between the benign and malignant pulmonary lesions in the four indices (P < 0.01) by t test and t' test. Lower pulsatility index, lower resistance index, lower peak systolic velocity and higher end diastolic velocity were characteristics of malignancy.     

Understanding negative bias temperature instability in the context of hole trapping (Invited Paper)

Hole trapping is often considered a parasitic component clouding the real degradation mechanism that is responsible for the negative bias temperature instability (NBTI). As such, it is often dealt with in a rather sketchy way that lacks physical rigor. We review hole trapping mechanisms that go beyond the conventional elastic tunneling mechanism by including structural relaxation and field effects. Contrary to some previous studies, it is shown that the rich spectrum of experimentally observed features of the most commonly observed defect in amorphous oxides, the E′ center, is consistent with experimental data available for NBTI. In particular, we show that a full model that includes the creation of E′ centers from their neutral oxygen vacancy precursors and their ability to be repeatedly charged and discharged prior to total annealing is consistent with a first stage of degradation. In a second stage, positively charged E′ centers can trigger the depassivation of P_b centers at the Si/ SiO₂ interface or K_N centers in oxynitrides to create an unpassivated silicon dangling bond. We formulate a complete model and evaluate it against experimental data.     

An in situ synthesis of mesoporous SBA-16/hydroxyapatite for ciprofloxacin release: in vitro stability and cytocompatibility studies

The present work developed a biomaterial (HA/SBA-16) based on the growth of calcium phosphate (HA) particles within an organized silica structure (SBA-16) to evaluate its application as a drug delivery system. The samples were charged with ciprofloxacin as a model drug and in vitro release assays were carried out. The samples were characterized by elemental analysis (CHN), Fourier transform infrared spectroscopy, nitrogen adsorption, scanning electron microscopy (SEM), transmission electron microscopy (TEM), small angle X-ray scattering (SAXS) and X-ray diffraction. The results obtained by TEM, SEM and SAXS reveal a well-defined cubic arrangement of a uniform spherical mesoporous structure, an intrinsic characteristic of these materials, which indicated that SBA-16 and HA/SBA-16 could potentially encapsulate bioactive molecules by means of ordered mesopores. It was found that both surface interaction and pore volume affect the rate and amount of ciprofloxacin released from the mesoporous materials. In vitro assays were performed to evaluate the adhesion, viability, and growth behavior of human adipose tissue-derived stem cells (hADSC) on SBA-16 and HA/SBA-16 nanocomposites to verify their potential as a scaffold for application in bone–tissue engineering using MTT assay and alkaline phosphatase activity tests. The results showed that the materials are promising systems for bone repair, providing a good environment for the adhesion and proliferation of rat mesenchymal stem cells and hADSC in vitro.     

Advanced low viscosity synthetic passenger vehicle engine oils

Premium quality synthetic passenger vehicle engine oils have been marketed by the authors' company since the early 1970s. During this time, the performance benefits of synthetic-based engine oils have been documented in a wide variety of engine and vehicle tests. The purpose of this paper is to demonstrate that, with the use of synthetic base oils and advanced additive technology, low viscosity oils can be formulated that have high fuel efficiency but which retain superior engine protection and performance reserves. Specifically, two synthetic engine oils, an SAE OW–40 and an SAE OW–30, have been developed that exceed the highest industry standards in both US (AP1)and European (ACEA) fuel economy and durability engine tests. The high quality of this technology is demonstrated in industry-standard engine and laboratory performance tests, as well as non-standard tests, such as extended-length engine tests, vehicle fuel economy tests, high mileage chassis rolls tests, and extended oil drain ‘over-the-road’ vehicle tests.     

Signing the Unsigned: Robust Surface Reconstruction from Raw Pointsets

We propose a modular framework for robust 3D reconstruction from unorganized, unoriented, noisy, and outlierridden geometric data. We gain robustness and scalability over previous methods through an unsigned distance approximation to the input data followed by a global stochastic signing of the function. An isosurface reconstruction is finally deduced via a sparse linear solve. We show with experiments on large, raw, geometric datasets that this approach is scalable while robust to noise, outliers, and holes. The modularity of our approach facilitates customization of the pipeline components to exploit specific idiosyncracies of datasets, while the simplicity of each component leads to a straightforward implementation.     

Soybean whole-plant ensiled with chitosan and lactic acid bacteria: Microorganism counts,fermentative profile,and total losses

Chitosan is a biopolymer derived from chitin deacetylation, present in the exoskeleton of crustaceans and insects. Chitosan has been evaluated as rumen modulator and silage additive due to its antimicrobial properties. The objective of this study was to determine the effects of both chitosan and a bacterial additive on microbiological quality, chemical composition, nutrient in vitro degradation, fermentative profile, and total losses of whole-soybean plant silage (SS) harvested at R6 stage. Four treatments in a factorial arrangement were randomly assigned to 40 experimental minisilos as no additives (CON), 8 g/t fresh forage of microbial inoculant (INO; Kera SIL, Kera Nutrição Animal, Bento Gonçalves, Brazil); 5 g/kg of fresh forage chitosan (CHI); and CHI + INO. Microbial inoculant was composed of Lactobacillus plantarum (4.0 × 10¹⁰ cfu/g) and Propionibacterium acidipropionici (2.6 × 10¹⁰ cfu/g). The CHI and INO alone increased counts of lactic bacteria and anaerobic bacteria and decreased counts of mold and yeast in SS. The CHI or INO alone increased in vitro degradation of dry matter, crude protein, and neutral detergent fiber, and decreased nonfiber carbohydrate content of SS. Chitosan increased NH₃-N and lactate concentrations and decreased ethanol concentration in SS. The CHI increased dry matter recovery from SS; INO increased silage aerobic stability. The combination of CHI+INO showed the lowest value of gas losses. In general, the combination of CHI and INO had small positive effects on gas losses of SS; however, both CHI or INO alone improved nutrient in vitro degradation and decreased mold and yeast in SS. Chitosan or INO utilization improves SS quality.