Treatment implications of past trauma in borderline personality disorder

Recent research and clinical experience have shown childhood trauma to be common in the histories of patients with borderline personality disorder. This article reviews the association between borderline personality disorder and early trauma, and how an awareness of the role of trauma may improve the treatment of patients with this disorder. Particularly when early trauma is in the form of childhood abuse, clinicians may be better able to understand the difficulties these patients experience in relational skills, affect tolerance, behavioral control, self-identity, and self-worth. Clinicians may be able to facilitate a stronger therapeutic alliance through acknowledgement of the patient's victimization and empathy with the effects of early trauma on the patient's life. Reframing the patient's experience as a consequence of childhood trauma is essential, especially when making traditional interventions such as interpretation and confrontation. The role of trauma in the development of borderline personality disorder suggests the need for modification of models of individual, family, and group psychotherapies that may allow more productive and successful treatment.     

Visual recognition memory in high- and low-risk infant pigtailed macaques (Macaca nemestrina).

Pigtailed macaque infants were administered a series of visual recognition problems adapted from a standardized test developed for use with human infants. The subjects were classified as either low risk or high risk. The low-risk animals were normal, whereas the high-risk animals had developmental problems (e.g., hypoxia, failure-to-thrive) that sometimes are correlated with cognitive deficits later in life in humans. The test consisted of a series of problems in which two identical abstract black-and-white patterns were presented for a study period, followed by a two-part test trial in which the previously exposed pattern was paired with a novel one. Looking time to each target was recorded. The low-risk group easily differentiated novel from previously seen targets. The high-risk group gave no evidence of recognition. The results have implications for an animal model to examine factors contributing to intellectual deficits in human infants. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Complex learning by low-birth-weight and normal-birth-weight juvenile pigtailed macaques (Macaca nemestrina).

As a group, human low-birth-weight (LBW) infants are at risk for a range of developmental problems including intellectual deficits later in life. However, in human studies it is difficult to separate the effects of LBW from the effects of socioeconomic status and competence of caregivers. In order to eliminate such confounding variables, we studied complex learning by LBW and normal-birth-weight (NBW) juvenile pigtailed macaques. The animals were given a battery of learning tasks, which included nonmatch-to-sample, match-to-sample, and a conditional test in which the color of the stimulus board dictated whether the problem was nonmatch- or match-to-sample. NBW subjects showed reliably better performance than LBW subjects on all three tasks. LBW performance was influenced by the relative novelty and familiarity of the correct and incorrect stimuli, with familiar stimuli consistently preferred over novel stimuli. These results suggest that LBW infants may use different strategies than NBW infants in solving such problems. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The insect exoskeleton: A natural structural composite

Through untold centuries of evolutionary development, the insect exoskeleton has become a highly optimized structure suited to a variety of demanding duties. Microscopic examination of the bessbeetle cuticle indicates that it is a composite consisting of layered plies having fiber orientations that alternate in a dual helicoidal pattern. Further, the geometry and size of the reinforcing fibers varies with the position of the ply. Several interesting structures discovered in the insect exoskeleton may provide fodder for new ideas on composite joining, ply orientation and fiber size and geometry.     

A novel PMOS SOI polysilicon transistor

An advanced silicon-on-insulator (SOI) PMOS polysilicon transistor, featuring an inverted gate electrode and self-aligned source/drain and gate/channel regions, is developed and characterized. Selective oxidation is used to form self-aligned thin polysilicon channel regions with thicker source/drain polysilicon regions. The gate electrode is formed by a high-energy boron implant into the underlying silicon substrate. Since the gate oxide is formed over single-crystal silicon rather than polysilicon, an improvement in gate oxide integrity is possible. The resulting SOI PMOS device is suitable for high-density static random access memory (SRAM) circuit applications and exhibits excellent short-channel behavior with an on/off current ratio exceeding six orders of magnitude     

An advanced 0.5-μm CMOS disposable TiN LDD/salicide spacerprocess

An advanced 0.5-μm CMOS technology which features disposable TiN spacers to define both lightly doped drain (LDD) implantation and self-aligned silicided source, drain, and gate regions is discussed. Since the LDD implantation sequences are reversed using the disposable TiN spacers, this process results in CMOS devices with low salicided junction leakage, reduced source/drain lateral diffusion, and shallow phosphorus N^- and boron P^- regions for improved short-channel behavior     

Status congruency as a predictor of job satisfaction and life stress.

Administered questionnaires to 2,080 United States Navy enlisted men grouped according to occupational specialties. A status congruency measure was developed and used to determine the degree to which an S was in step with peers within his occupational category relative to duty time, pay grade, age, and marital status. An individual's score on this measure was found to be significantly and uniquely predictive of his reported life stress and job satisfaction. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

"Axis I and Axis II disorders as predictors of prospective suicide attempts: Findings from the Collaborative Longitudinal Personality Disorders Study": Correction to Yen et al (2003).

Reports an error in "Axis I and Axis II disorders as predictors of prospective suicide attempts: Findings from the Collaborative Longitudinal Personality Disorders Study" by Shirley Yen, Tracie Shea, Maria Pagano, Charles A. Sanislow, Carlos M. Grilo, Thomas H. McGlashan, Andrew E. Skodol, Donna S. Bender, Mary C. Zanarini, John G. Gunderson and Leslie C. Morey (Journal of Abnormal Psychology, 2003[Aug], Vol 112[3], 375-381). On p. 378, the values in the "95% CI" column of Table 1 are incorrect. The correct values are given in the far right column of the table provided in the erratum. (The following abstract of the original article appeared in record 2003-05990-006.) This study examined diagnostic predictors of prospectively observed suicide attempts in a personality disorder (PD) sample. During 2 years of follow-up, 58 participants (9%) reported at least 1 definitive suicide attempt. Predictors that were examined include 4 PD diagnoses and selected Axis I diagnoses (baseline and course). Multivariate logistic regression analyses indicated that baseline borderline personality disorder (BPD) and drug use disorders significantly predicted prospective suicide attempts. Controlling for baseline BPD diagnosis, proportional hazards analyses showed that worsening in the course of major depressive disorder (MDD) and of substance use disorders in the month preceding the attempt were also significant predictors. Therefore, among individuals diagnosed with PDs, exacerbation of Axis I conditions, particularly MDD and substance use, heightens risk for a suicide attempt. (PsycINFO Database Record (c) 2010 APA, all rights reserved)