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91.
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Xiaoshuai Li Zhengwei Yuan Xiaowei Wei Hui Li Guifeng Zhao Jiaoning Miao Di Wu Bo Liu Songying Cao Dong An Wei Ma Henan Zhang Weilin Wang Qiushi Wang Hui Gu 《Journal of materials science. Materials in medicine》2016,27(4):77
Spina bifida aperta are complex congenital malformations resulting from failure of fusion in the spinal neural tube during embryogenesis. Despite surgical repair of the defect, most patients who survive with spina bifida aperta have a multiple system handicap due to neuron deficiency of the defective spinal cord. Tissue engineering has emerged as a novel treatment for replacement of lost tissue. This study evaluated the prenatal surgical approach of transplanting a chitosan–gelatin scaffold seeded with bone marrow mesenchymal stem cells (BMSCs) in the healing the defective spinal cord of rat fetuses with retinoic acid induced spina bifida aperta. Scaffold characterisation revealed the porous structure, organic and amorphous content. This biomaterial promoted the adhesion, spreading and in vitro viability of the BMSCs. After transplantation of the scaffold combined with BMSCs, the defective region of spinal cord in rat fetuses with spina bifida aperta at E20 decreased obviously under stereomicroscopy, and the skin defect almost closed in many fetuses. The transplanted BMSCs in chitosan–gelatin scaffold survived, grew and expressed markers of neural stem cells and neurons in the defective spinal cord. In addition, the biomaterial presented high biocompatibility and slow biodegradation in vivo. In conclusion, prenatal transplantation of the scaffold combined with BMSCs could treat spinal cord defect in fetuses with spina bifida aperta by the regeneration of neurons and repairmen of defective region. 相似文献
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Liang Zhang Ting Wang Bo Yuan Bin Yu Zhichao Chen 《Advanced Engineering Materials》2023,25(11):2201823
Herein, an innovative powder-cored wire arc additive manufacturing (PC-WAAM) process is proposed to fabricate γ-TiAl thin-walled intermetallic alloy. The metallography, phase composition, and mechanical properties at different thin-wall locations are characterized. The results show that the alternatively distributed layer-like microstructure composed of α2 (Ti3Al) and γ (TiAl) phases is obtained along the building direction. The content of α2 phase exhibits the tendency of decreasing from the bottom to top region. This unique microstructure characteristic is closely related to the typical thermal cycling history during deposition. Moreover, the tensile strength and microhardness of the top region are lower than the middle and bottom region. In general, the current PC-WAAM technique shows promising capability of fabricating γ-TiAl intermetallic alloy with low cost. This work becomes a valuable reference for understanding the evolution mechanism of microstructure and paves the way for the flexible and customized additive manufacturing of γ-TiAl alloy. 相似文献
96.
Collapse is an essential operation for the manipulation of area features in digital data generalization. This operation can be categorized into two types: complete collapse and partial collapse. The former is composed of another two types: area-to-point and area-to-line collapse. In this paper, a set of algebraic models built upon the operators in mathematical morphology is described for the area-to-line collapse and partial collapse operations. For the area-to-line collapse operation, a modified skeleton algorithm is presented. For the partial collapse operation, a procedure is designed which consists of a set of operations, i.e., the skeletonization, separation of areal and linear parts, simplification of areas and an overlay operation. These models are tested using real map data sets. 相似文献
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近年来,支持多标准的LDPC译码器已逐渐成为研究的热点.与传统译码器相比,所设计的LDPC译码器具有以下优点:1.实现了一个码率、码长可配置结构,进而可以支持多种标准;2.采用了一种改进型TPMP算法,使译码器的存储器容量大大减少,避免了因分块LDPC码的非规则性所造成的数据冲突问题;3.采用基于SIMD处理器的硬件结构,实现了硬件的高度规整性,易于芯片布局布线;4.设计了一个6级可配置流水线,可分时构造校验节点处理单元和变量节点处理单元,提高了硬件利用率和系统数据吞吐率.用这种架构实现了一个同时支持CMMB和DTMB两个标准的多标准LDPC译码器;芯片规模为75万门,时钟频率为220MHz,数据吞吐率为300Mbps. 相似文献
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针对人脸在跟踪过程中可能存在大幅度的倾斜、旋转、遮挡以及肤色干扰等问题,提出一种基于在线修正的人脸跟踪算法.该算法当人脸检测失效时,人脸跟踪模块将用于提取目标参数;而在人脸跟踪过程中,为减小由连续跟踪造成的累积误差,利用人脸实时检测机制新检测到的人脸目标参数来修正跟踪模块的参数,包括跟踪窗口的位置和尺度,从而利用了人脸检测和人脸跟踪各自的优点.通过实验,其结果表明,该算法能够精确地跟踪复杂姿态下的人脸目标,并且能够解决肤色干扰和遮挡的问题,具有很好的适应性和鲁棒性.另外,将在线修正的跟踪方法应用于娱乐游戏控制,为人机交互提供了新的方式. 相似文献
100.
We consider the problem of revenue maximization on multi‐unit auctions where items are distinguished by their relative values; any pair of items has the same ratio of values to all buyers. As is common in the study of revenue maximizing problems, we assume that buyers' valuations are drawn from public known distributions and they have additive valuations for multiple items. Our problem is well motivated by sponsored search auctions, which made money for Google and Yahoo! in practice. In this auction, each advertiser bids an amount bi to compete for ad slots on a web page. The value of each ad slot corresponds to its click‐through‐rate, and each buyer has her own per‐click valuations, which is her private information. Obviously, a strategic bidder may bid an amount that is different with her true valuation to improve her utility. Our goal is to design truthful mechanisms avoiding this misreporting. We develop the optimal (with maximum revenue) truthful auction for a relaxed demand model (where each buyer i wants at most di items) and a sharp demand model (where buyer i wants exactly di items). We also find an auction that always guarantees at least half of the revenue of the optimal auction when the buyers are budget constrained. Moreover, all of the auctions we design can be computed efficiently, that is, in polynomial time. 相似文献