Diagnostic and prognostic relevance of malignancy-associated changes in cervical smears

OBJECTIVE: For approximately 15 years, malignancy-associated changes (MACs) have been consistently found by means of high-resolution cytometry in different tissues, especially in visually normal appearing cervical cells. Their biologic nature is not yet fully understood. The aim of this investigation was to assess the expression of MACs in cervical smears and to evaluate their prognostic relevance. STUDY DESIGN: This study was performed on normal intermediate cells obtained from 53 cytologically positive and 78 cytologically negative cervical smears. From a second sample, 31 cases showing negative cytology were selected for a prospective longitudinal study. Densitometric and texture features were generated, and MACs were described on the basis of multivariate discriminant analysis. RESULTS: Discrimination between positive and negative cases was possible, with a correct classification rate of approximately 80%. After a mean period of 29.5 months, we noted no statistically significant increase in the incidence of cervical intraepithelial neoplasia in the group of healthy but MAC-positive women as compared to those who were MAC negative. CONCLUSION: MACs were constantly expressed in the epithelium of the cervix. Although their prognostic relevance remains unclear, MACs play an important role in the effort to automate cervical cytology.     

Permeation of Zidovudine and Probenecid from Oily Bases Containing Alcohols Through Rat Skin

Permeation of zidovudine (3'-azido-3'-deoxythymidine, AZT) and probenecid from oily bases containing an alcohol through rat skin was examined. Isopropyl myristate (IPM), as an oily vehicle, showed a penetration enhancing effect for AZT and probenecid. Ethanol, n-propanol, and n-butanol were used as additives in IPM and were examined for their own permeation and the enhancing effect on the permeation of AZT and probenecid. The skin permeation of AZT and probenecid from IPM was enhanced by addition of the alcohol in IPM. The degree of the enhancement was decreased with increasing lipophilicity of the alcohol used. me permeation rate of the drug from those systems was shown to be governed by penetration-enhancing effects of the oily base and alcohol, and the penetration of the alcohol itself through the skin.     

内蒙古煤系高岭土作为FCC催化剂基质的研究

研究两种内蒙古煤系高岭土（1^＃、2^＃）的化学组成、晶体结构并与苏州高岭土进行了比较。对三种高岭土进行酸改性，利用BET、吡啶-TPD和微反测试分别研究改性前后高岭土的性能特点。并将内蒙古高岭土1^＃与苏州高岭土采用半合成方法合成了FCC催化剂，测定了其裂化活性。研究结果表明，内蒙古1^＃具有较良好的晶体结构和化学组成，经酸改性后比表面积大大增加，具有合适的孔径分布，裂化活性较好，可以取代苏州高岭土作为FCC催化剂的基质。     

柳海矿运输大巷返修工程深部软岩支护设计研究

通过现场调查、室内试验以及理论分析,柳海矿运输大巷支护现状进行分析研究,总结破坏原因。根据现场工程地质条件、岩石特性和破坏特点,确定软岩变形力学机制为高应力膨胀性软岩,并提出采用预留刚隙柔层支护技术进行支护。     

花艺教室：荆丛亦风流

运动的环热烈的爱//圆点示爱//纯洁爱情//心心相印//透过玻璃的美     

200kA预焙槽节能降耗的几点尝试

通过对200kA预焙槽节能方面做的几点尝试，探索出了200kA预焙电解槽在节约能源方面的措施，并取得了较好的节能效果。     

可追溯的绿色安全猪肉生产系统研究

现在，养猪生产者滥用激素、微量元素和违禁药物饲养生猪，而消费者却无法识别这种猪肉，严重地威胁着消费者的食品卫生安全。为此，应用射频识别技术，采用综合软件管理，以一维条形码实行三网合一查验的方式来建立猪肉生产卫生安全跟踪系统，是保障消费者食品卫生安全的理想方法。     

安全:爆破工程永恒的主题——2001年重大拆除爆破工程回顾

通过对2001年我国重大拆除爆破工程的回顾,认为在提高大面积毫秒非电起爆网络可靠性,控制爆破震动、扬尘、噪声等环境影响,与机械清理配合,实现快速施工等方面取得了进展与突破;对几起爆破安全事故进行了初步分析.为保证拆除爆破工程安全,在加强理论研究、开展技术创新、建立科学有序的管理制度等方面提出了建议意见.     

吸收雷达波包装材料的研究进展

论述了吸收雷达波包装材料的基本组成及其选择原则，在此基础上讨论了吸波材料的吸波原理及影响吸波性能的因素，并指出了吸波包装材料的开发现状和应用进展及其发展万向。     

混凝土喷锚技术在宝珠寺水电站边坡防护中的应用

混凝土喷锚支护可提高边坡岩土的结构强度和抗变形刚度,增强边坡的整体稳定性和承载能力.本文根据宝珠寺水电站左右岸边坡主要采用混凝土喷锚支护的工程实践,介绍了施工方案设计、材料要求、施工方法、技术措施,以及现场质量管理和检测等问题.