A distributed adverse drug reaction detection system using intelligent agents with a fuzzy recognition‐primed decision model

Discovering unknown adverse drug reactions (ADRs) in postmarketing surveillance as early as possible is highly desirable. Nevertheless, current postmarketing surveillance methods largely rely on spontaneous reports that suffer from serious underreporting, latency, and inconsistent reporting. Thus these methods are not ideal for rapidly identifying rare ADRs. The multiagent systems paradigm is an emerging and effective approach to tackling distributed problems, especially when data sources and knowledge are geographically located in different places and coordination and collaboration are necessary for decision making. In this article, we propose an active, multiagent framework for early detection of ADRs by utilizing electronic patient data distributed across many different sources and locations. In this framework, intelligent agents assist a team of experts based on the well‐known human decision‐making model called Recognition‐Primed Decision (RPD). We generalize the RPD model to a fuzzy RPD model and utilize fuzzy logic technology to not only represent, interpret, and compute imprecise and subjective cues that are commonly encountered in the ADR problem but also to retrieve prior experiences by evaluating the extent of matching between the current situation and a past experience. We describe our preliminary multiagent system design and illustrate its potential benefits for assisting expert teams in early detection of previously unknown ADRs. © 2007 Wiley Periodicals, Inc. Int J Int Syst 22: 827–845, 2007.     

Fast algorithms for determining the linear complexity of sequences over GF(p/sup m/) with period 2/sup t/n

We prove a result which reduces the computation of the linear complexity of a sequence over GF(p^m) (p is an odd prime) with period 2n (n is a positive integer such that there exists an element bisinGF(p^m), bⁿ=-1) to the computation of the linear complexities of two sequences with period n. By combining with some known algorithms such as the Berlekamp-Massey algorithm and the Games-Chan algorithm we can determine the linear complexity of any sequence over GF(p^m) with period 2^tn (such that 2 ^t|p^m-1 and gcd(n,p^m-1)=1) more efficiently     

济钢中厚板厂的技术改造与发展

结合济钢中厚板厂二期和三期工程、开发管线钢项目和大板坯连铸高效改造及炉外精炼改造，介绍了该厂的技术改造项目，对今后的发展进行了阐述．     

含V、N无缝钢管表面外折缺陷产生原因的分析

通过对鞍钢生产的部分批号V、N微合金强化无缝钢管及生产该钢管的原料连铸坯和连轧管坯的表面缺陷进行研究，分析了含V、N钢管表面外折缺陷的成因，提出了改善钢管表面质量的方法。采用改进后工艺生产的无缝管，其表面外折废品量大幅度降低。     

掺Nd纳米ZnO薄膜特性研究

研究了用真空蒸发法在玻璃衬底上制备稀土掺杂纳米ZnO薄膜结构、导电性及光透射性能。结果显示 ,在 5 0 0℃氧化、热处理稀土元素Nd掺杂后能够明显改善纳米ZnO薄膜的结构特性 ,薄膜的晶粒尺寸随掺杂含量的增加而减小。掺Nd使ZnO薄膜的电性能有所改善但使纳米ZnO薄膜的光透射性有所降低。     

水轮机过流部件磨蚀问题的研究与防护

针对我国高含沙水流中运行的水轮机组的过流部件的磨蚀这个长期存在的疑难问题，开展研究工作，在分析水轮机过流部件泥沙磨损、空化破坏各自的磨损机理、特点、影响因素、预测模型等的基础上，总结出水轮机过流部件的磨蚀主要是泥沙磨损、空化破坏及它们的联合作用，提出水轮机过流部件磨蚀的主要防护措施，为最终解决水轮机过流部件磨蚀问题提供了理论依据。图6幅，表1个。     

小型水电站联网改造应注意的几个问题

针对铜鼓县小水电站联网时存在的问题及其不利影响进行了分析，井提出了改进途径，指出小水电站的联网改造应立足安全，争取效益。     

Multimode parameter extraction for multiconductor transmissionlines via single-pass FDTD and signal-processing techniques

We present two approaches to extract the broadband multimode parameters of guided wave structures from a single-pass finite-difference time-domain (FDTD) simulation. They include a two-dimensional (2-D) Fourier transform (FT) algorithm and a super-resolution estimation of signal parameters via rotational invariance technique (ESPRIT) algorithm. Comparison is made to show the superiority of the super-resolution approach. As a typical application, a three-line coupled microstrip structure is studied. After a single-pass FDTD simulation, broadband multimode parameters such as propagation constants, modal-field templates, and modal impedances are extracted and verified against published data obtained by the spectral-domain method. The main feature of this parameter-extraction methodology is that it decouples the computational electromagnetics engine (in this case, the FDTD simulator) from the post-processing parameter-extraction algorithm, thus providing more flexibility and connectivity among the various simulation tools     

溅射——气体——聚集共沉积法制备金属／金属（介质）复合团簇镶嵌薄膜

提出了溅射－气体－聚集共沉积制备金属／金属（介质）复合团簇镶嵌薄膜的新方法，并利用该方法成功地在方华膜衬底上制备了系列Ｆｅ／Ａｇ及ＣａＦ２复合团簇镶嵌薄膜样品。透射电镜分析结果表明，样品中Ｆｅ（Ｃｕ）团簇都较好地镶嵌于Ａｇ（ＣａＦ２）基质中，其结构为两种材料的多晶共存形态。进一步分析发现，与块材相比，Ｆｅ／Ａｇ样品中Ｆｅ团簇晶格常数呈现出不同程度的收缩，而Ｃｕ／ＣａＦ２样品中Ｃｕ团簇晶格常数则呈现出不同程度的膨胀。运用附加压力的模型对该现象进行了解释。     

珠江口盆地开平凹陷油气聚集条件分析

珠江口盆地自新生代以来,曾先后受到不同方向张应力的作用,造成了不同时期构造体系的交叉叠合.中中新世以来构造运动强烈,并具有东强西弱的特点,对油气的运移与聚集产生了重要影响.开平凹陷的剧烈断裂和断陷活动始于始新世,并在同期沉积了巨厚的文昌组.晚渐新世以后,由于断裂活动非常微弱,在成熟的烃源岩与其上地层之间缺乏有效的油源断层,因而自生自储、近距离运移可能是开平凹陷油气聚集的基本特征.在凹陷内部,因重力滑动和欠压实泥岩共同作用所形成的KPll-1构造带可能是该区最具有油气远景的地区.