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41.
图像纹理增强过程中容易丢失平滑区域纹理细节,而分数阶微分增强虽然能够非线性保留平滑区域纹理细节,但对频率分辨率敏感。针对这个问题,提出一种基于小波变换的分数阶微分纹理增强算法,应用于平扫计算机断层扫描(CT)图像的肝脏肿瘤区域的纹理增强。首先,通过小波变换将图像感兴趣区分解成多个子带分量;其次,基于分数阶微分定义构造一个带补偿参数的分数阶微分掩膜;最后,使用该掩膜与每个高频子带分量进行卷积并利用小波逆变换重组图像感兴趣区。实验结果表明,该方法在使用较大分数阶次显著增强肿瘤区域的高频轮廓信息的同时,有效地保留了低频平滑的纹理细节:增强后的肝细胞癌区域与原区域相比,信息熵平均增加36.56%,平均梯度平均增加321.56%,平均绝对差值平均为9.287;增强后的肝血管瘤区域与原区域相比,信息熵平均增加48.77%,平均梯度平均增加511.26%,平均绝对差值平均为14.097。 相似文献
42.
Guangbo Zeng Dongqing Zhang Liuming Yan Baohua Yue Ting Pan Yidong Hu Shufa He Hongbin Zhao Jiujun Zhang 《International Journal of Hydrogen Energy》2021,46(39):20664-20677
Side-chain optimized poly (2,6-dimethyl-1,4-phenylene oxide)-g-poly (styrene sulfonic acid) (PPO-g-PSSA) is designed with balanced water-resistance and sulfonation degree. The PPO-g-PSSA is synthesized by controlled atom-transfer radical polymerization (ATRP) from brominated poly (2,6-dimethyl-1,4-phenylene oxide) (PPO-xBr) and ethyl styrene-4-sulfonate and followed by hydrolysis. A series of PPO-g-PSSA are prepared possessing different bromination degree (x) of PPO-xBr and polymerization degree (m) of the side-chains and the water-resistances of the fabricated membranes are investigated. The results show that a PPO-g-PSSA at relatively low x (x < 0.2) and high m (m > 4) exhibits good balance between the water-resistance and the sulfonation degree. Namely, it displays suitable proton conductivity with compromised water-resistance. Moreover, a maximum ion exchange capacity (IEC) of 3.24 mmol g?1 is reached without the sacrifice of water-resistance. In addition, PPO-g-0.08PSSA-13 and PPO-g-0.14PSSA-4 are chosen characterized by thermogravimetric analysis, proton conductivities and mechanical properties. At 90% RH, the optimized PPO-g-0.08PPSA-13 possesses a proton conductivity of 37.9 mS cm?1 at 40 °C and 45.5 mS cm?1 at 95 °C, respectively. 相似文献
43.
Wen Cao Zhonghua Zhou Chenyu Li Qun Wang Yue Huang Shirley Shen 《Ceramics International》2021,47(2):1807-1818
Sodalime float (SF) glass is widely used in our societies and industries. Hydrothermal corrosion method is one of the effective ways to prepare a superhydrophobic glass, but there is still lack of knowledge about hydrothermal corrosion behavior and mechanism of SF glass. We have hydrothermally treated SF glass at 180 °C for different time, and tried to reveal the aqueous corrosion process of SF glass. We have characterized the morphologies and chemical compositions of samples, and found that (1) the two sides of SF glass have different corrosion resistances, and (2) a multilayer structural coating with a nanoflake layer (Mg-rich gel layer), a nanowire layer (Ca-rich gel layer), and a porous layer (etched layer) is formed on the air-side of SF glass. Based on the experimental results, we have proposed an aqueous corrosion mechanism of SF glass. The insights of the hydrothermal corrosion behaviors and mechanism provide helpful guidelines to glass surface structural control and functionalization. 相似文献
44.
45.
Yue Gao Miao-miao Zhang Xiao-peng Guo Wen-jian Li Dong Lu 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》2020,95(5):1290-1297
Toxicity caused by the accumulation of butanol in fermentation media is an important factor limiting the concentration of butanol. There is currently no systematic research in place investigating the butanol tolerance mechanism of bacteria such as Clostridium acetobutylicum, which adapts to butanol stress and regulates its growth and metabolism. Here, research results related to the butanol tolerance of C. acetobutylicum are reviewed to understand the molecular basis of changes in butanol-tolerant strains. Organic solvent-tolerant bacteria play an important role in the fields of biofuel production, enzyme preparation and bioremediation. An analysis of limitations of the application of organic solvent-tolerant bacteria has revealed that future research should focus on combining the microbial tolerance phenotype with specific utilization to achieve an optimal balance between organic solvent tolerance and production. This review serves as a reference for the improvement and engineering of strains that tolerate organic solvents. © 2019 Society of Chemical Industry 相似文献
46.
Xiao-Guang Yue Guang Zhang Qu Wu Fei Li Xian-Feng Chen Gao-Feng Ren Mei Li 《稀有金属(英文版)》2015,(2):125-132
In order to predict the wearing of stellite alloys,the related methods of rare metals data processing were discussed. The method of opposite degree(OD) algorithm was put forward to predict the wearing of stellite alloys.OD algorithm is based on prior numerical data, posterior numerical data and the opposite degree between numerical forecast data. To compare the performance of predicted results based on different algorithms, the back propagation(BP) and radial basis function(RBF) neural network methods were introduced. Predicted results show that the relative error of OD algorithm is smaller than those of BP and RBF neural network methods. OD algorithm is an effective method to predict the wearing of stellite alloys and it can be applied in practice. 相似文献
47.
西藏江达县白格村金沙江右岸于2018年10月11日和2018年11月3日先后发生2次大规模滑坡—堰塞湖堵江事件,溃堰洪水对下游拉哇库区不良地质体的稳定性造成不同程度的影响。为保障下游水电站建设安全,对拉哇库区主要不良地质体建立了基于星载InSAR技术、无人机技术和地面传感器实时监测的“天空地”一体化监测预警体系,以多维空间采集技术获取变形信息,通过智能监控平台对信息及时进行处理、分析和可视化呈现,利用平台、短信等方式向相关人员进行分级告警,取得了较好的应用效果。 相似文献
48.
Dr. Yahu A. Liu Dr. Qihui Jin Qiang Ding Dr. Xueshi Hao Tingting Mo Shanshan Yan Dr. Yefen Zou Dr. Zhihong Huang Xiaoyue Zhang Wenqi Gao Dr. Tom Y.-H. Wu Chun Li Dr. Badry Bursalaya Dr. Michael Di Donato Dr. You-Qing Zhang Lisa Deaton Dr. Weijun Shen Dr. Brandon Taylor Anwesh Kamireddy Dr. George Harb Dr. Jing Li Dr. Yong Jia Dr. Andrew M. Schumacher Dr. Bryan Laffitte Dr. Richard Glynne Dr. Shifeng Pan Dr. Peter McNamara Dr. Valentina Molteni Dr. Jon Loren 《ChemMedChem》2020,15(16):1562-1570
Loss of β-cell mass and function can lead to insufficient insulin levels and ultimately to hyperglycemia and diabetes mellitus. The mainstream treatment approach involves regulation of insulin levels; however, approaches intended to increase β-cell mass are less developed. Promoting β-cell proliferation with low-molecular-weight inhibitors of dual-specificity tyrosine-regulated kinase 1A (DYRK1A) offers the potential to treat diabetes with oral therapies by restoring β-cell mass, insulin content and glycemic control. GNF4877, a potent dual inhibitor of DYRK1A and glycogen synthase kinase 3β (GSK3β) was previously reported to induce primary human β-cell proliferation in vitro and in vivo. Herein, we describe the lead optimization that lead to the identification of GNF4877 from an aminopyrazine hit identified in a phenotypic high-throughput screening campaign measuring β-cell proliferation. 相似文献
49.
Yan Xiong Xianwu Du Mingyu Xiang Hao Wang Weimin Wang Zhengyi Fu 《Journal of the European Ceramic Society》2018,38(12):4167-4172
The densification behaviors of pure B4C and B4C-ZrO2 mixtures were compared during hot pressing. The results showed that in-situ formed ZrB2 effectively enhanced the densification process of B4C-ZrO2 mixtures, more significantly during the intermediate stage. Within the relative density ranging from 0.75 to 0.90, the B4C-15?wt%ZrO2 mixture (B15Z) achieved the maximum densification rate as twice much as that of pure B4C. The stress exponent n>3 indicated plastic deformation was the dominant densification mechanism of B15Z. The viscosities of plastic flow were evaluated using Murray-Rodger-William equation and the viscosity of B15Z was only a quarter of that in pure B4C. The sintering activation energy was calculated to be 305.9?kJ/mol for pure B4C and 197?kJ/mol for B15Z, respectively. It was proposed that the lower viscosity of plastic flow and activation energy accelerated the sliding and propagating motions of plastic flow, by which underlain the enhanced densification behaviors of B4C-ZrO2 mixtures. 相似文献
50.
Breast cancer is the most frequently diagnosed cancer in women worldwide. The disease and its treatments exert profound effects on an individual’s physical and mental health. There are many factors that impact an individual’s risk of developing breast cancer, their response to treatments, and their risk of recurrence. The community of microorganisms inhabiting the gastrointestinal tract, the gut microbiota, affects human health through metabolic, neural, and endocrine signaling, and immune activity. It is through these mechanisms that the gut microbiota appears to influence breast cancer risk, response to treatment, and recurrence. A disrupted gut microbiota or state of ‘dysbiosis’ can contribute to a biological environment associated with higher risk for cancer development as well as contribute to negative treatment side-effects. Many cancer treatments have been shown to shift the gut microbiota toward dysbiosis; however, the microbiota can also be positively manipulated through diet, prebiotic and probiotic supplementation, and exercise. The objective of this review is to provide an overview of the current understanding of the relationship between the gut microbiota and breast cancer and to highlight potential strategies for modulation of the gut microbiota that could lead to improved clinical outcomes and overall health in this population. 相似文献