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81.
82.
Li-Jane Shih Jia-Yu Wang Jing-Yao Jheng An-Ci Siao Yen-Yue Lin Yi-Wei Tsuei Yow-Chii Kuo Chih-Pin Chuu Yung-Hsi Kao 《International journal of molecular sciences》2020,21(23)
Prostate cancer (PCa) is a reproductive system cancer in elderly men. We investigated the effects of betel nut arecoline on the growth of normal and cancerous prostate cells. Normal RWPE-1 prostate epithelial cells, androgen-independent PC-3 PCa cells, and androgen-dependent LNCaP PCa cells were used. Arecoline inhibited their growth in dose- and time-dependent manners. Arecoline caused RWPE-1 and PC-3 cell cycle arrest in the G2/M phase and LNCaP cell arrest in the G0/G1 phase. In RWPE-1 cells, arecoline increased the expression of cyclin-dependent kinase (CDK)-1, p21, and cyclins B1 and D3, decreased the expression of CDK2, and had no effects on CDK4 and cyclin D1 expression. In PC-3 cells, arecoline decreased CDK1, CDK2, CDK4, p21, p27, and cyclin D1 and D3 protein expression and increased cyclin B1 protein expression. In LNCaP cells, arecoline decreased CDK2, CDK4, and cyclin D1 expression; increased p21, p27, and cyclin D3 expression; had no effects on CDK1 and cyclin B1 expression. The antioxidant N-acetylcysteine blocked the arecoline-induced increase in reactive oxygen species production, decreased cell viability, altered the cell cycle, and changed the cell cycle regulatory protein levels. Thus, arecoline oxidant exerts differential effects on the cell cycle through modulations of regulatory proteins. 相似文献
83.
Jia‐Wei Li Yu‐Jing Chiu Chia‐Jui Chang Hung‐Chieh He Yi‐Hsuan Tu Kuan‐Ting Lin Yu‐Liang Lin Tzu‐Hsun Kao Hsun‐Hao Hsu Hsiao‐Fan Tseng Tien‐Chang Lu Jiun‐Tai Chen 《大分子材料与工程》2020,305(1)
Polyimides (PIs) possess excellent mechanical properties, thermal stability, and chemical resistance and can be converted to carbon materials by thermal carbonization. The preparation of carbon nanomaterials by carbonizing PI‐based nanomaterials, however, has been less studied. In this work, the fabrication of PI nanofibers is investigated using electrospinning and their transformation to carbon nanofibers. Poly(amic acid) carboxylate salts (PAASs) solutions are first electrospun to form PAAS nanofibers. After the imidization and carbonization processes, PI and carbon nanofibers can then be obtained, respectively. The Raman spectra reveal that the carbon nanofibers are partially graphitized by the carbonization process. The diameters of the PI nanofibers are observed to be smaller than those of the PAAS nanofibers because of the formation of the more densely packed structures after the imidization processes; the diameters of the carbon nanofibers remain similar to those of the PI nanofibers after the carbonization process. The thermal dissipation behaviors of the PI and carbon nanofibers are also examined. The infrared images indicate that the transfer rates of thermal energy for the carbon nanofibers are higher than those for the PI nanofibers, due to the better thermal conductivity of carbon caused by the covalent sp2 bonding between carbon atoms. 相似文献
84.
85.
本文以魔芋葡甘聚糖、玉米醇溶蛋白为成膜基质,添加不同含量(1%、2%、3%)的纳米TiO2,以流延方式制备纳米TiO2/魔芋葡甘聚糖/玉米醇溶蛋白复合膜,并对复合膜的微观结构、热性能、力学性能、疏水性、水蒸气透过率和抑菌性能进行了分析。结果表明,纳米TiO2与魔芋葡甘聚糖、玉米醇溶蛋白间发生相互作用,有良好的相容性;添加纳米TiO2使复合膜表面粗糙度增加,复合膜热稳定性和疏水性增强,力学性能降低;纳米TiO2添加量为1% wt时,复合膜的水蒸气透过率(5.7×10?13 g·cm/(cm2·s·Pa))和溶胀率(16.4%)最小,水接触角值(99.6 °)最大;复合膜对金黄色葡萄球菌和大肠杆菌有明显的抑制作用,对枯草芽孢杆菌的抑制作用不明显。本研究为纳米TiO2/魔芋葡甘聚糖/玉米醇溶蛋白复合膜作为包装材料的开发与应用提供一定参考依据。 相似文献
86.
Use of Soy Protein and Microbial Transglutaminase as a Binder in Low-sodium Restructured Meats 总被引:1,自引:0,他引:1
ABSTRACT: Pork sticks were prepared by mixing pork chucks with various amounts of bisulfite-treated soy protein and microbial transglutaminase (MTGase) to evaluate the potential of using soy protein as meat binders. According to tensile strength, the favorable conditions for binding the restructured pork chunks were 5% soy protein containing 0.2% NaHSO3 and 20 unit MTGase/g, and the setting condition was 60 min at 40°C. The tensile strength and cooking yield of restructured pork sticks made with bisulfite-treated soy protein and MTGase were much higher than those of using salt, suggesting the high potential of using soy protein and MTGase as binders in products where NaCl reduction is desired. 相似文献
87.
The effects of a low-modulus high-strain interleaf layer, introduced at the midplane, on unidirectional carbon/epoxy laminates
under flexural loading were investigated. The apparent energy-to-fail of the laminates increased significantly whereas the
maximum load decreased slightly upon interleaving. Real-time microscopic observations during static flexure tests at the lowest
deflection rate indicated a dramatic change of failure mode from the dominantly compressive fracture of the baseline laminate
to the dominantly tensile fracture process upon interleaving. Failure modes of interleaved and baseline laminates showed no
significant changes with test rate in the deflection rate range of 10−6 to 100 m/sec. 相似文献
88.
89.
核事故后果评价研究进展 总被引:3,自引:0,他引:3
回顾了国内外在核事故后果评价领域开展的概率风险评价、实时后果评价、事故后的后果评价技术与方法研究的发展历程,对后果评价研究在大气弥散模型的要求与发展、利用环境监测数据估算源项、食物链模型与事故季节性、剂量估算与防护措施、核与辐射突发事件(小尺度)响应、决策支持技术以及放射性物质长距离迁移问题等方面进行了讨论与分析。近年来,随着我国核能事业的迅猛发展,需要加强和发展核事故与突发事件的后果评价和应急响应技术。 相似文献
90.
Li-Chung Wu Dong-Jiing Doong Chia Chuen Kao 《International journal of remote sensing》2013,34(5):1303-1318
In this study, a two-dimensional continuous wavelet transform is applied to quantify the non-homogeneity from remote-sensing wave images. Our study shows that the non-homogeneity index, which is proposed here, is capable of identifying the degree of non-homogeneity from the wave-field images. However, the influence from the edges of the wave-field image should be considered in analysis. The calculated results from the simulated wave fields and from the natural wave-field images reveal that the non-homogeneity index is influenced by the bathymetry inside the area of the ocean-wave image. It conforms to the character of the natural wave non-homogeneity. After discussing the wave characteristics from the wave-field image with a high non-homogeneity index, an inhomogeneous algorithm is recommended for obtaining accurate and reasonable wave results from the wave image. 相似文献