Microscopic studies of the influence of technological conditions on technical parameters of photopolymer flexographic plates

The quality of printing plates is one of the important factors influencing the accuracy of flexographic printed copies. The essential technological parameters determining the quality of flexographic plates comprise the dot gain, resolution, and profile of the printing elements. In this work, these parameters were studied using stereoscopic microscopy. These studies enabled us to determine the effect of technological parameters of photochemical preparation of flexographic plates on their resolution, tone transfer characteristics, and the profile of printing elements. It has been found that the quality of flexographic plates depends on the time of the preliminary and the main exposure of the photopolymer plates, the time of solvent washout, and the washout brushes height.     

A Posteriori Estimates Using Auxiliary Subspace Techniques

A posteriori error estimators based on auxiliary subspace techniques for second order elliptic problems in \(\mathbb {R}^d\ (d\ge 2)\) are considered. In this approach, the solution of a global problem is utilized as the error estimator. As the continuity and coercivity of the problem trivially leads to an efficiency bound, the main focus of this paper is to derive an analogous effectivity bound and to determine the computational complexity of the auxiliary approximation problem. With a carefully chosen auxiliary subspace, we prove that the error is bounded above by the error estimate up to oscillation terms. In addition, we show that the stiffness matrix of the auxiliary problem is spectrally equivalent to its diagonal. Several numerical experiments are presented verifying the theoretical results.     

In vivo degradation of poly(DTE carbonate) membranes. Analysis of the tissue reactions and mechanical properties

Different bioabsorbable polymers and their co-polymers have been used to construct an optimal material for guided bone regeneration applications. Our aim was to evaluate a novel bioabsorbable material in a soft tissue environment. In this study, a poly(DTE carbonate) membrane (0.2–0.3 mm) was implanted into 20 NZW rabbits’ subcutaneous pouches for 6, 12, 24 and 52 weeks. The material was evaluated by means of histological reactions to the material and mechanical properties of the membrane. Based on this study, it can be concluded that poly(DTE carbonate) elicited a very modest foreign body reaction in the soft tissues. This reaction was uniform throughout the study. Varying amounts of calcification was seen in the fibrous capsule surrounding the implant. The number of calcified bodies did not correlate to healing time.     

Unsteady Flow Simulation and Erosion Assessment in a Ditch Network of a Drained Peatland Forest Catchment in Eastern Finland

We developed and applied a computational model for simulating unsteady flow in a drainage network of a boreal forested peatland site. The input to the model was the hourly runoff produced by a hydrological model. The simulations of the flow in the ditch network were performed using an iterative procedure for solving the Saint-Venant equations that govern the flow in each of the network channels. These equations were solved separately for each ditch branch, and the flow depths at the junctions were corrected using the method of characteristics. The model was applied to the drainage network of a peatland catchment in Eastern Finland over a period of 15 months. Because flow resistance in the ditches depended strongly on flow conditions, flow resistance (Manning’s n) was introduced as a function of discharge. The model was calibrated and validated against field data and the simulation results were further applied to assess erosion risk. The highest risk of erosion occurred during long lasting flows induced by snowmelt at ditch sections with a steep slope and a large upstream area. These model results can aid in the design and siting of water protection measures within the drained area.     

Social interaction and reflection for behaviour change

This article introduces the theme issue on social interaction and reflection for behaviour change. A large body of research exists on systems designed to help users in changing their behaviours, for instance, to exercise more regularly or to reduce energy consumption. Increasingly, these systems focus on multiple users, often to encourage open-ended reflection rather than prescribing a particular course of action. As background for this theme issue, this article presents a literature review on behaviour change support systems that focus on social interaction and reflection. The review highlights five key approaches amongst these systems: social traces, social support, collective use, reflection-in-action, and reflection-on-action. Each approach offers unique benefits, but also challenges for the design of behaviour change support systems. We highlight how the articles in this theme issue contribute to our current understanding of these five approaches, and beyond that, set out some broad directions for future work.     

Hydrolysis behaviour of crosslinked poly(ester anhydride) networks prepared from functionalised poly(ε-caprolactone) precursors

Biodegradable poly(ester anhydride) networks based on functionalised poly(ε-caprolactone) precursors with different hydrophobicities, molecular weights and architectures were synthesised. Networks that were prepared from the star-shaped precursors clearly showed higher gel contents and crosslinking densities than the networks that were prepared from the linear precursors. Functionalising with different alkenylsuccinic anhydrides and/or varying the molecular weight of the precursor, the thermal properties, surface hydrophobicity and erosion of the crosslinked networks were widely tailored. The dissolution behaviour of the networks changed dramatically as the molecular weight of the precursor increased from 2000 to 4000 g/mol or the alkenyl chain of the alkenylsuccinic anhydride increased from 8 to 18 carbons. The networks that were prepared from the lower molecular weight precursors, without an alkenyl chain or with an 8 carbon alkenyl chain, lost their mass in a few days, whereas the networks that were prepared from higher molecular weight precursors or contained a hydrophobic 18 carbon alkenyl chain did not show any mass loss over a period of 8 weeks.     

Drying of foam-formed mats from virgin pine fibers

The purpose of this work was to select an efficient drying technique for drying of highly porous thick fiber foam mats with minimum impact on their structure after forming and drainage. Thick fiber mats were produced from wood fibers using foam-forming technology and dried using several different drying methods. The mixture of pine fibers and surfactant (foaming agent) in water was blended using a high-speed blender. After fiber foam generation, a sample mold was filled with wet fiber foam, and after drainage, drying experiments were performed. For comparison, experiments were carried out in an oven, an impingement dryer assisted with a vacuum, and a combined impingement-infrared dryer. At low moisture contents, through-air drying experiments were also carried out. Drying curves, temperature profiles, and shrinkage were measured from the produced mat structures. The most promising drying technique in this study was the combined impingement-infrared drying, used until the fiber mat became permeable, followed by through-air drying until the desired final moisture content was achieved.     

Inhalation exposure to nanosized and fine TiO2 particles inhibits features of allergic asthma in a murine model

Background

Nowadays, effects of fine particulate matter (PM_2.5) are well-documented and related to oxidative stress and pro-inflammatory response. Nevertheless, epidemiological studies show that PM_2.5 exposure is correlated with an increase of pulmonary cancers and the remodeling of the airway epithelium involving the regulation of cell death processes. Here, we investigated the components of Parisian PM_2.5 involved in either the induction or the inhibition of cell death quantified by different parameters of apoptosis and delineated the mechanism underlying this effect.

Results

In this study, we showed that low levels of Parisian PM_2.5 are not cytotoxic for three different cell lines and primary cultures of human bronchial epithelial cells. Conversely, a 4 hour-pretreatment with PM_2.5 prevent mitochondria-driven apoptosis triggered by broad spectrum inducers (A23187, staurosporine and oligomycin) by reducing the mitochondrial transmembrane potential loss, the subsequent ROS production, phosphatidylserine externalization, plasma membrane permeabilization and typical morphological outcomes (cell size decrease, massive chromatin and nuclear condensation, formation of apoptotic bodies). The use of recombinant EGF and specific inhibitor led us to rule out the involvement of the classical EGFR signaling pathway as well as the proinflammatory cytokines secretion. Experiments performed with different compounds of PM_2.5 suggest that endotoxins as well as carbon black do not participate to the antiapoptotic effect of PM_2.5. Instead, the water-soluble fraction, washed particles and organic compounds such as polycyclic aromatic hydrocarbons (PAH) could mimic this antiapoptotic activity. Finally, the activation or silencing of the aryl hydrocarbon receptor (AhR) showed that it is involved into the molecular mechanism of the antiapoptotic effect of PM_2.5 at the mitochondrial checkpoint of apoptosis.

Conclusions

The PM_2.5-antiapoptotic effect in addition to the well-documented inflammatory response might explain the maintenance of a prolonged inflammation state induced after pollution exposure and might delay repair processes of injured tissues.     

Job strain and risk indicators for cardiovascular disease in young female nurses.

This study examined the possible effects of job demands, decision latitude, and job-related social support on risk indicators for cardiovascular disease (CVD) in 165 female nurses. Job strain was measured with the Job Content Questionnaire; CVD risk was measured with insulin, total cholesterol, triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), fibrinogen, tissue-type plasminogen activator (tPA) antigen, tPA activity, plasminogen activator inhibitor-1 antigen, and blood pressure. Multivariate analysis of covariance and regression analyses revealed no effects of either job strain or social support on these risk indicators. All risk indicators deteriorated with age and body mass index. Oral contraceptive use improved fibrinolytic potential and increased HDL-C but had adverse effects on TG levels. Results suggest that in healthy young women job strain is not associated with an unfavorable metabolic or fibrinolytic risk profile. (PsycINFO Database Record (c) 2010 APA, all rights reserved)