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31.
This study uses a neural field model to investigate computational aspects of population coding and decoding when the stimulus is a single variable. A general prototype model for the encoding process is proposed, in which neural responses are correlated, with strength specified by a gaussian function of their difference in preferred stimuli. Based on the model, we study the effect of correlation on the Fisher information, compare the performances of three decoding methods that differ in the amount of encoding information being used, and investigate the implementation of the three methods by using a recurrent network. This study not only rediscovers main results in existing literatures in a unified way, but also reveals important new features, especially when the neural correlation is strong. As the neural correlation of firing becomes larger, the Fisher information decreases drastically. We confirm that as the width of correlation increases, the Fisher information saturates and no longer increases in proportion to the number of neurons. However, we prove that as the width increases further--wider than (sqrt)2 times the effective width of the turning function--the Fisher information increases again, and it increases without limit in proportion to the number of neurons. Furthermore, we clarify the asymptotic efficiency of the maximum likelihood inference (MLI) type of decoding methods for correlated neural signals. It shows that when the correlation covers a nonlocal range of population (excepting the uniform correlation and when the noise is extremely small), the MLI type of method, whose decoding error satisfies the Cauchy-type distribution, is not asymptotically efficient. This implies that the variance is no longer adequate to measure decoding accuracy. 相似文献
32.
K Kurozumi T Nishida K Nakao M Nakahara M Tsujimoto 《Canadian Metallurgical Quarterly》1998,22(8):853-7; discussion 857-8
Lymph node metastasis is a critical prognostic factor for gastric cancer. In the present investigation we examined clinicopathologic factors influencing the metastatic processes to the lymph mode and their prognostic importance. A randomly selected group of 98 patients with adenocarcinomas of the stomach who underwent gastrectomy plus systematic lymph node dissection at Osaka Police Hospital from 1991 to 1996 were analyzed. Altogether 37 (38%) cancers were positive for CD44 variant 6 (v6) staining, 31 (32%) were intermediately stained, and 30 (30%) were negative. CD44-v6 expression correlated well with lymph node metastasis. Expression of CD44-v6 and lymphatic invasion were independent risk factors for metastatic lymph nodes. Among the patients with CD44-v6-positive and lymphatic invasion-positive cancers, 88% had lymph node metastasis, whereas only 13% of patients negative for both factors had lymph node metastasis. Although CD44-v6 expression and lymphatic invasion have been reported to be risk factors for recurrence and a poor prognosis, in this investigation these factors were found not to be significant for hematogenous and lymphatic recurrences or overall survival rates. Thus expression of CD44-v6 and lymphatic invasion may regulate lymph node metastases from gastric cancer. 相似文献
33.
Low-loss single-mode fibres with GeO2-doped SiO2 cores have been made by the c.v.d. method and the loss spectrum from 0.6 to 1.8 ?m measured. The minimum loss of the fibre with suitably designed parameters, characterised by the refractive-index difference and the core diameter, was 0.75 dB/km at 1.05 ?m. 相似文献
34.
35.
In order to achieve the high-rate production of fibre preforms, the deposition mechanism in the VAD process has been investigated. The particle deposition rate was found to depend on the Reynolds number of the flame stream. The high-rate preform production of 4.5 g/min was attained by applying this result to the preform fabrication technique. 相似文献
36.
Nakahara Motohiro Chida Kazunori Hanawa Fumiaki Sudo Shoichi Horiguchi Masaharu 《Electronics letters》1980,16(3):102-103
A low-loss and wide-bandwidth optical fibre in the long-wavelength region has been fabricated by the v.a.d. method. Loss at 1.3 ?m is 0.98 dB/km and 6 dB down bandwidth is 1600 MHz km at 1.26 ?m. 相似文献
37.
A large preform for 220 km of fibre was fabricated with the vapour-phase axial deposition (VAD) method. The deposition rate for the core was 1.7 g/min. Optical fibre drawn from a part of the preform had optical attenuation of 0.58 dB/km and bandwidth 500 MHz km0.9 at a wavelength of 1.3 ?m. 相似文献
38.
The stochastic mechanism of synchronous firing in a population of neurons is studied from the point of view of information geometry. Higher-order interactions of neurons, which cannot be reduced to pairwise correlations, are proved to exist in synchronous firing. In a neuron pool where each neuron fires stochastically, the probability distribution q(r) of the activity r, which is the fraction of firing neurons in the pool, is studied. When q(r) has a widespread distribution, in particular, when q(r) has two peaks, the neurons fire synchronously at one time and are quiescent at other times. The mechanism of generating such a probability distribution is interesting because the activity r is concentrated on its mean value when each neuron fires independently, because of the law of large numbers. Even when pairwise interactions, or third-order interactions, exist, the concentration is not resolved. This shows that higher-order interactions are necessary to generate widespread activity distributions. We analyze a simple model in which neurons receive common overlapping inputs and prove that such a model can have a widespread distribution of activity, generating higher-order stochastic interactions. 相似文献
39.
40.
J Nakayama K Hamano Y Shimakura N Iwasaki C Nakahara N Imoto K Kobayashi T Arinami H Hamaguchi 《Canadian Metallurgical Quarterly》1997,28(6):335-337
BACKGROUND: Most adult anatomical texts state that the deep inguinal ring is situated midway between the anterior superior iliac spine and the pubic tubercle. The aim of this study was to determine if this was true in prepubescent children. METHODS: A total of 107 inguinal ligaments and canals were measured during inguinal operations in 80 children (68 boys, age range 1-118 months). RESULTS: The length of the inguinal ligament increased from a median of 4.3 cm (range 3.6-6.8) at less than 1 year of age to 7.5 cm (range 6.7-10.1) at over 4 years of age. The internal ring was situated medial to the midpoint of the inguinal ligament throughout childhood. The ratio of internal ring to public tubercle over inguinal ligament length was 42% (range 27-58) at less than 2 years; and 34% (range 25-46) at over 4 years. The inguinal canal remained short (median 1 cm (range 0.7-1.1) at less than 2 years, and median 1.1 cm (range 0.7-2.3) at over 4 years) suggesting that growth of the inguinal region in this age group occurs outside the canal. CONCLUSIONS: These results have implications for the siting of incisions, and question the necessity of opening the inguinal canal in children. 相似文献