3-D manipulation of millimeter- and micro-sized objects using an acoustically excited oscillating bubble

This communication describes novel 3-D manipulations of objects using an acoustically excited oscillating bubble deposited on a hydrophobic rod tip. The oscillating bubble captures various millimeter- and micron-sized neighboring objects including glass and polystyrene beads (~100 μm), fish egg, and live water flea (~1 mm). The captured objects are carried in a 3-D space by traversing the bubble tip, and released at desired positions by simply turning off the oscillation. Carrying performance is characterized along with high-speed imaging of oscillating bubbles by varying the frequency and amplitude of the acoustic excitation and the carrying speed. The higher the oscillation amplitude, the higher the carrying efficiency. The maximum carrying speed is measured at over 3 mm/s. This method is effective with a low-level acoustic excitation (bubble oscillation amplitude relative to the diameter ≤5%), possibly providing a cost-effective, soft-contact manipulating tool for handling biological objects.     

Application of maximum entropy principle for reliability-based design optimization

The maximum entropy principle (MEP) is used to generate a natural probability distribution among the many possible that have the same moment conditions. The MEP can accommodate higher order moment information and therefore facilitate a higher quality PDF model. The performance of the MEP for PDF estimation is studied by using more than four moments. For the case with four moments, the results are compared with those by the Pearson system. It is observed that as accommodating higher order moment, the estimated PDF converges to the original one. A sensitivity analysis formulation of the failure probability based on the MEP is derived for reliability-based design optimization (RBDO) and the accuracy is compared with that by finite difference method (FDM). Two RBDO examples including a realistic three-dimensional wing design are solved by using the derived sensitivity formula and the MEP-based moment method. The results are compared with other methods such as TR-SQP, FAMM + Pearson system, FFMM + Pearson system in terms of accuracy and efficiency. It is also shown that an improvement in the accuracy by including more moment terms can increase numerical efficiency of optimization for the three-dimensional wing design. The moment method equipped with the MEP is found flexible and well adoptable for reliability analysis and design.     

Robust background maintenance by estimating global intensity level changes for dynamic scenes

The maintenance of relevant backgrounds under various scene changes is very crucial to detect foregrounds robustly. We propose a background maintenance method for dynamic scenes including global intensity level changes caused by changes of illumination conditions and camera settings. If the global level of the intensity changes abruptly, the conventional background models cannot discriminate true foreground pixels from the background. The proposed method adaptively modifies the background model by estimating the level changes. Because there are changes caused by moving objects as well as global intensity level changes, we estimate the dominant level change over the whole image regions by mean shift. Then, the problem caused by saturated pixels are handled by an additional scheme. In the experiments for dynamic scenes, our proposed method outperforms previous methods by adaptive background maintenance and handling of saturated pixels.     

Proteomic analysis of sera of asymptomatic,early‐stage patients with Wilson's disease

Wilson's disease (WD) is characterized by excessive accumulation of intracellular copper in liver and extrahepatic tissues, leading to significant oxidative stress and tissue damage. To date, several diagnostic biomarkers for WD such as serum ceruloplasmin, serum or urine copper levels and copper content in liver have been identified. However, these biomarkers may not be convincing for the diagnosis in some WD patients. To identify additional novel diagnostic biomarkers, we compared the serum protein profiles of asymptomatic childhood WD patients (n=20), without neurologic manifestation or liver cirrhosis, with normal controls (n=13). Fourteen spots, five up‐regulated and nine down‐regulated (>2‐fold), were differentially expressed in WD patients in comparison to normal control on 2‐DE. Among them, three spots were down‐regulated in both male and female WD. MS/MS analysis revealed that the three spots were complement component C3, complement factor B and alpha‐2 macroglobulin. By comparative proteome analysis, complement component C3, complement factor B and alpha‐2 macroglobulin, which are related to oxidative stress and inflammation, turned out to be good candidates for novel diagnostic biomarkers for early stages of WD.     

Effect of interlayer on structure and performance of anode-supported SOFC single cells

To lower the operating temperatures in solid oxide fuel cell (SOFC) operations, anode-supported SOFC single cells with a single dip-coated interlayer were fabricated and the effect of the interlayer on the electrolyte structure and the electrical performance was investigated. For the preparation of SOFC single cells, yttria-stabilized zirconia (YSZ) electrolyte, NiO-YSZ anode, and 50% YSZ-50% strontium-doped lanthanum manganite (LSM) cathode were used. In order to characterize the cells, scanning electron microscopy (SEM) and atomic force microscopy (AFM) were utilized and the gas (air) permeability measurements were conducted for gas tightness estimation. When the interlayer was inserted onto NiO-YSZ anode, the surface roughness of anode was diminished by about 40% and dense crack-free electrolytes were obtained. The electrical performance was enhanced remarkably and the maximum power density was 0.57W/cm(2) at 800 degrees C and 0.44W/cm(2) at 700 degrees C. On the other hand, the effect of interlayer on the gas tightness was negligible. The characterization study revealed that the enhancement in the electrical performance was mainly attributed to the increase of ion transmission area of anode/electrolyte interface and the increase of ionic conductivity of dense crack-free electrolyte layer.     

Developable polynomial surface approximation to smooth surfaces for fabrication parameters of a large curved shell plate by Differential Evolution

This paper presents a simple and efficient method to approximate a developable surface to a compound design surface by a polynomial. It is required to predict a final shape of roll bending in the fabrication of a curved shell plate. The roll bending process usually makes the cylindrical or conical curvature from an initial flat plate. It means that the final shape is developable or the surface representation has zero Gaussian curvature. The fabrication shape is important in order to estimate process parameters of roller bending.An optimization problem is formulated to determine the polynomial surface which is in the closest proximity to the design surface or the given shell plate, which is subjected to developability. The results and the efficiency of this algorithm are verified and evaluated by applying it to some shell plates which are obtained from a real ship model. The predicted bending shape becomes fundamental information in determining more process parameters for the fabrication of a compound curved shell plate.     

Scalable optical hypercube-based interconnection network for massively parallel computing

Two important parameters of a network for massively parallel computers are scalability and modularity. Scalability has two aspects: size and time (or generation). Size scalability refers to the property that the size of the network can be increased with nominal effect on the existing configuration. Also, the increase in size is expected to result in a linear increase in performance. Time scalability implies that the communication capabilities of a network should be large enough to support the evolution of processing elements through generations. A modular network enables the construction of a large network out of many smaller ones. The lack of these two important parameters has limited the use of certain types of interconnection networks in the area of massively parallel computers. We present a new modular optical interconnection network, called an optical multimesh hypercube (OMMH), which is both size and time scalable. The OMMH combines positive features of both the hypercube (small diameter, high connectivity, symmetry, simple routing, and fault tolerance) and the torus (constant node degree and size scalability) networks. Also presented is a three-dimensional optical implementation of the OMMH network. A basic building block of the OMMH network is a hypercube module that is constructed with free-space optics to provide compact and high-density localized hypercube connections. The OMMH network is then constructed by the connection of such basic building blocks with multiwavelength optical fibers to realize torus connections. The proposed implementation methodology is intended to exploit the advantages of both space-invariant free-space and multiwavelength fiber-based optical interconnect technologies. The analysis of the proposed implementation shows that such a network is optically feasible in terms of the physical size and the optical power budget.     

Effect of deposition temperature on dielectric properties of PECVD Ta2O5 thin film

Tantalum oxide film formation by plasma-enhanced chemical vapour deposition (PECVD) using TaCl₅ as a source material was examined. The effects of deposition temperature on the formation, structure and electric properties of the Ta₂O₅ film were investigated for Al/Ta₂O₅/ p-Si (MTS) capacitors. The deposition rate and refractive index increased with increasing deposition temperature. It was found that the structure of Ta₂O₅ deposited by PECVD was amorphous as-deposited. However, crystalline -Ta₂O₅ of hexagonal structure was formed by a 700 °C, 1 h heat treatment in argon. Capacitance and relative dielectric constant of the PECVD Ta₂O₅ were found to be 2.54 fF m^–2 and 23.5, respectively. The PECVD films obtained in this study have higher dielectric constants and remarkably better general film characteristics than those obtained by other deposition methods.     

Preparation and characterization of poly(2,6-dimethyl-1,4-phenylene oxide) and Nylon 6 graft copolymer

Summary A poly(2,6-dimethyl-1,4-phenylene oxide) (PPO, 1) macroinitiator having carbonylcaprolactam groups was prepared through metalation of methyl group of PPO and subsequent modification to introduce carboxyl group, acid chloride group, and finally carbonylcaprolactam group. Anionic ring opening copolymerization of -caprolactam took place onto the macroinitiator to give a graft copolymer of PPO and Nylon 6. The structure of intermediate materials and the graft copolymer were characterized by ¹H NMR, ¹³C NMR, and IR spectroscopy. Glass transition temperatures and melting temperatures of these materials are also reported. It is found that the copolymer has a microphase-separated morphology even with segment molecular weight as low as 3000.     

Optical binary de Bruijn networks for massively parallel computing: design methodology and feasibility study

The interconnection network structure can be the deciding and limiting factor in the cost and the performance of parallel computers. One of the most popular point-to-point interconnection networks for parallel computers today is the hypercube. The regularity, logarithmic diameter, symmetry, high connectivity, fault tolerance, simple routing, and reconfigurability (easy embedding of other network topologies) of the hypercube make it a very attractive choice for parallel computers. Unfortunately the hypercube possesses a major drawback, which is the complexity of its node structure: the number of links per node increases as the network grows in size. As an alternative to the hypercube, the binary de Bruijn (BdB) network has recently received much attention. The BdB not only provides a logarithmic diameter, fault tolerance, and simple routing but also requires fewer links than the hypercube for the same network size. Additionally, a major advantage of the BdB network is a constant node degree: the number of edges per node is independent of the network size. This makes it very desirable for large-scale parallel systems. However, because of its asymmetrical nature and global connectivity, it poses a major challenge for VLSI technology. Optics, owing to its three-dimensional and globalconnectivity nature, seems to be very suitable for implementing BdB networks. We present an implementation methodology for optical BdB networks. The distinctive feature of the proposed implementation methodology is partitionability of the network into a few primitive operations that can be implemented efficiently. We further show feasibility of the presented design methodology by proposing an optical implementation of the BdB network.