From categorial to dimensional diagnosis

The concepts of categorical and dimensional assessment approaches and their specific advantages--and disadvantages are described. A combination of both concepts within the framework of Multiple Assessment of Psychiatric Disturbances is proposed. This includes the different levels of behavioural and emotional disturbances, different assessment methods, the situational specificity of behavioural and emotional disturbances and individually tailored and treatment related assessment procedures. Thereby two phases are distinguished. In the first phase basic procedures of the Multiple Assessment of Psychiatric Disturbances are accomplished, which cover a broad spectrum of behavioural and emotional problems. In the second phase a differentiated picture of the-specific disturbance is assessed by using symptom-specific instruments of the Multiple Assessment of Psychiatric Disturbances. In a case report the diagnostic procedure is explained.     

An inverse method for determining elastic material properties and a material interface

A numerical procedure which integrates optimization, finite element analysis and automatic finite element mesh generation is developed for solving a two-dimensional inverse/parameter estimation problem in solid mechanics. The problem consists of determining the location and size of a circular inclusion in a finite matrix and the elastic material properties of the inclusion and the matrix. Traction and displacement boundary conditions sufficient for solving a direct problem are applied to the boundary of the domain. In addition, displacements are measured at discrete points on the part of the boundary where the tractions are prescribed. The inverse problem is solved using a modified Levenberg-Marquardt method to match the measured displacements to a finite element model solution which depends on the unknown parameters. Numerical experiments are presented to show how different factors in the problem and the solution procedure influence the accuracy of the estimated parameters.     

Engineering design and mechatronics: The schemebuilder project

The paper describes the development of a software design aid for use at the conceptual stage of engineering design. It is intended for use in the design of mechatronic products but has wider potential uses. Early approaches were based on function structures and tables of options and the system that evolved allows the assembly of schemes linked by matching their input and output ports. A database of components is provided which can be accessed via different indexes and the designer can easily create and compare alternative schemes at the concept stage.A bond graph approach is used to define the interconnections between components. This allows correct port matching but also provides for future development such as constraint propagation through the design and links to simulation tools.     

Scattering of an induced surface electromagnetic field by fatiguecracks in ferromagnetic metals

In crack detection and sizing by the alternating current field measurement technique, U-shaped wires or coils excited by a high-frequency AC current source can be used to induce the surface field in the workpiece. The authors present a modeling technique for the interaction of a fatigue crack in a ferromagnetic metal with the surface field resulting from an inducer with two U-shaped wires. This work is an extension of a previous modeling technique to have developed for infinitely long (one-dimensional) cracks. In the present technique, the boundary of the fatigue crack is approximated by a circular arc, leading to a formulation for an efficient computation of the field-flaw interaction. Various numerical and experimental results supporting the modeling and illustrating the behavior of the magnetic field and electric potential at the metal surface around circular-arc cracks are presented     

Evaluation of a commercial process for collection and cooling of beef offals by a temperature function integration technique.

The hygienic adequacy of a commercial process for the collection and cooling of beef offals was assessed by a temperature function integration technique. The diverse operations for collection of offals were inspected. The rates of product movement through those operations, and the temperatures of products at the time of their being packed, were determined. From that information, four of the nine product types were selected for examination of their temperature histories during the assembly and cooling of the cartoned products. The products selected encompassed product at near-body and near-air-ambient temperatures at the time of packaging, product in the largest and smallest cartons used in the process, and product with relatively short and long residence times in an unchilled carton stack assembly area. Twenty-one temperature histories were collected for each of the products, and the possible proliferation of an indicator organism, Escherichia coli, calculated for each temperature history. The results were assessed against a temperature function integration criterion derived from studies of beef carcass and cartoned meat cooling processes. Products packaged at near-ambient temperature readily met with the criterion, but products packed at near-body temperatures did not comply. The latter non-compliance was extreme for product packaged in large cartons. However, the principal cause of non-compliance was identified as highly variable cooling conditions in the carton freezing facility. A brief survey of air speeds and temperatures within that facility indicated means by which product cooling could be better controlled.     

The Principles of Calculus of Behavior Scenarios of Complex Systems in the ECS

Theoretical results of the development of the principles of scenario calculus are presented, which are obtained in the framework of the design of an emergency control system (ECS). Relying on the suggested system concept of the formation of a scenario system, consideration is given to the principles of the construction of operations in scenario spaces, which account for specific features of the scenario analysis and the process of the decision-making in the ECS. Principal problems of the development of scenario calculus on the basis of a system approach are treated, the classification of operations on scenarios is given, and a number of operations on elements of the basic metacollection are formalized.     

Measuring probe for fast transients monitoring in gas insulatedsubstation

This paper describes the construction of four probes adjusted for fast transient monitoring in 123 kV SF₆ insulated substations. The primary requirement was the ability to monitor without distortion very fast transients containing frequencies up to 200 MHz. The measuring system was tested and calibrated with the help of computer modeling techniques. The verified experimental apparatus was then used for testing and calibrating the measuring probes. During the test, various effects on the measuring system characteristics were analyzed with respect to materials used for the components of the system     

Development of a heart monitoring system with high-Tc DC-SQUID gradiometers

We investigated different types of high-T_c DC-SQUID gradiometers with the aim to develop an one-channel heart monitoring system for non-invasive measurements in unshielded environment. This system could be used to obtain information about the patients condition in serial examinations and in emergency cases fast and stable. Step-edge and bicrystal Josephson junctions were used to prepare planar galvanically coupled thin film gradiometers and magnetometers. These sensors were used to carry out measurements in well-shielded and non-shielded environment and we compared the different noise properties and field gradient resolutions. With different types and sizes of high-T_c DC-SQUID sensors magnetocardiograms were measured in a magnetically shielded room. The influence of antenna configurations, SQUID parameters, and cooling conditions on the measurement of magnetocardiograms will be discussed. We investigated possibilities to suppress the earth magnetic field (with pairs of Helmholtz coils) and for noise field compensation in unshielded environment.     

Does histology influence outcome in childhood Hodgkin's disease? Results from the United Kingdom Children's Cancer Study Group

PURPOSE: Histology has been identified as an important prognostic factor in Hodgkin's disease (HD) in adults. Information regarding the impact of histology on outcome in childhood HD is scarce. This study determines the effect of histology on the overall survival (OS) or progression-free survival (PFS) in a national series of children treated in a standardized manner. PATIENTS AND METHODS: The results of treatment of 331 assessable patients, treated between January 1, 1982 and June 30, 1992, in the United Kingdom Children's Cancer Study Group (UKCCSG) Hodgkin's study I were reviewed to evaluate OS, PFS, and deaths according to stage and histology. Treatment was either involved-field radiation alone (stage IA) or chlorambucil, vinblastine, procarbazine, and prednisolone (ChlVPP) chemotherapy with or without mediastinal radiation. All were clinically staged at diagnosis. RESULTS: Nodular sclerosing (NS) HD was the most common histologic subtype (155 of 331 patients [47%]) and was uniformly distributed through all stages. Lymphocyte-depletion (LD) HD was extremely uncommon (< 1%). Mixed-cellularity (MC) HD had the highest relapse rate, but this was only significant (P < .05) in stage I patients who received local irradiation alone. There was no other statistically significant difference in OS and PFS between the various histologic subtypes. Multivariate analysis for PFS and OS confirmed that stage was the most important prognostic factor and that histology did not have an effect after stratification by stage. CONCLUSION: This study demonstrates that with effective multiagent chemotherapy, histologic subtype does not influence outcome. The high relapse rates in stage I MC subtype indicates that MC HD is biologically aggressive and systemic treatment with or without local irradiation may be indicated. The high relapse rate in stage IV patients appeared to be independent of histology.