Characterization of gamma irradiated concentrated aqueous solutions of chitosan/sodium alginate blends and their drug uptake‐release characters

Blends films based on different ratios of concentrated aqueous solutions of chitosan (CS) and sodium alginate (AG) in the presence of 1% of glutaraldehyde, as a cross‐linking agent for chitosan, were prepared by solution casting and then exposed to gamma irradiation. The formed blends were characterized by IR spectroscopic analysis, differential scanning calorimetry (DSC), and thermogravimetric analysis (TGA). The uptake‐release properties of CS/AG blends, taking ketoprofen as an example for drug, were also investigated. DSC thermograms of CS/AG blends revealed good miscibility was sustained between CS and AG. The water uptake and gel content of CS/AG blends was found to decrease by increasing the ratio of AG in the initial solution. The IR spectra indicated the formation of cross‐linking and hydrogen bonding, while the TGA study showed that the CS/AG blends displayed higher thermal stability than pure CS polymer. Based on Fick's law, it was demonstrated that the main parameters affecting the release of ketoprofen drug from the CS/AG blend hydrogels were composition and pH. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011     

信息编码在中小型制造企业信息化体系中的设计与应用

通过对一个中小型制造企业产品信息编码设计实例,说明中小制造企业在企业信息化建设中,必须重视对企业信息进行编码的基础性工作.     

Analytical expressions for intermodulation distortion of a MESFET small-signal amplifier using the nonlinear Volterra series

Using the nonlinear Volterra series representation, analytical expressions for the third-order intermodulation distortion power and intercept point for a MESFET small-signal amplifier are derived when its equivalent circuit is bilateral and includes the gate-to-drain capacitance (C_gd) explicitly as a nonlinear element. Previously developed analytical expressions treated C_gd as a linear element or incorporated it as a part of gate-to-source and drain-to-source capacitances (C_gs and C_ds). These new analytical expressions are then compared with experimental data and good agreement is obtained. The analytical expressions are also used to study the variation of intermodulation distortion with input power and frequency, and the effect of the individual nonlinear elements in the MESFET’s equivalent circuit.     

Effect of thermal storage on the performance of greenhouse

In this communication, thermal model of a greenhouse has been developed by incorporating the effect of water wall in the north side. Various temperatures, namely plant, water wall and room temperatures as a function of climatic and design parameters have been obtained by solving coupled single-order differential equation using Runge–Kutta method. Numerical methods have been carried out for a typical day of winter for Delhi condition. It has been observed that there is significant effect in the plant, room air and water temperatures due to change in fraction of solar radiation incident on north wall (F_n) and heat capacity of water wall. Experimental validation of the proposed model for a greenhouse with brick north wall has also been carried out. It has been observed that there is a fair agreement between experimental and theoretical values. Copyright © 2002 John Wiley & Sons, Ltd.     

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哈伯特储量发现模型是以勘探历史为背景的统计学模型，该模型不仅考虑了以往的发现率，而且考虑了当前的发现率，估算的最终或剩余储量更为准确，可靠，应用此模型对川南Ｐ１最终地质储量估算结果表明，在这个区带天然气最终可探明数百亿立方米，目前还有近七分之一的剩余地质储量尚待发现。     

The effects of discontinuity surface roughness on the shear strength of weathered granite joints

Surface roughness is one of the most important parameters governing the shear strength of rock discontinuities. Roughness types may vary based on genesis, physico-mechanical, and mineralogical properties of rocks. In this study, granite samples representing three different weathering degrees were selected to evaluate the effects of surface roughness and weathering degree on shear strength. To this aim, we determined the profile roughness coefficient (PRC), profile roughness angle (PRA), and joint roughness coefficient (JRC) for the selected fresh and weathered granite joint samples. Values of PRC were in the range of about 1.043–1.073, and PRA and JRC varied in the ranges of 16.67–21.45 and 12–18, respectively. Weathering led to the increment of joint surface roughness of the selected granitic joints due to the higher resistance of quartz crystals in the weathered matrix. However, the increment in surface roughness did not result in an increase in the shear strength. On the contrary, the shear strength of discontinuities dramatically decreased.     

Efficient multi‐hop wireless broadcast protocol in vehicular networks using automated threshold function design

Vehicular networking applications often use multi‐hop wireless broadcasting as a primary data dissemination mechanism. Therefore, protocols that efficiently and thoroughly propagate application data while adapting to a wide range of network density, vehicle distribution pattern, channel quality, and other conditions are critical for vehicular communications. Here, we design the Statistical Vehicular Broadcast (SVB) protocol to efficiently distribute data via multi‐hop broadcast in vehicular networks. First, we present an automated optimization technique for the design of threshold functions in statistical broadcasting methods. Next, we compare and analyze known statistical techniques, including different fundamental methods, assessment delay algorithms, and failsafe mechanisms. All combinations of these techniques are given threshold functions optimized using the proposed automated procedure then are evaluated in a wide range of simulations. High‐level statistical design principles and recommendations are established based on analysis of these results. Finally, we apply those principles to design SVB. It is evaluated in JiST/SWANS and is shown to achieve a high target reachability level while consuming less bandwidth than similar protocols across urban and highway vehicular networking scenarios.Copyright © 2014 John Wiley & Sons, Ltd.     

A modified rain attenuation prediction model for tropical V‐band satellite earth link

Radio wave propagation plays a very important part in the design and eventually dictates performance of space communication systems. Over time, the requirements of satellite communication have grown extensively where higher capacity communications systems are needed. Escalating demands of microwave and millimetre wave communications are causing frequency spectrum congestion. Hence, existing and future satellite system operators are planning to employ frequency bands well above 10 GHz. The challenge in operating at such high frequencies for communication purposes is that there exists stronger electromagnetic interaction between the radio signals and atmospheric hydrometeors. Such instances will degrade the performance of such high frequency satellite communication systems. The development of a revised model for a better‐improved rain fade prediction of signal propagations in tropical region is considered very important. Researchers and engineers can employ the model to accurately plan the future high frequencies satellite services. Copyright © 2014 John Wiley & Sons, Ltd.     

Biocompatible transferrin-conjugated sodium hexametaphosphate-stabilized gold nanoparticles: synthesis, characterization, cytotoxicity and cellular uptake

The feasibility of using gold nanoparticles (AuNPs) for biomedical applications has led to considerable interest in the development of novel synthetic protocols and surface modification strategies for AuNPs to produce biocompatible molecular probes. This investigation is, to our knowledge, the first to elucidate the synthesis and characterization of sodium hexametaphosphate (HMP)-stabilized gold nanoparticles (Au-HMP) in an aqueous medium. The role of HMP, a food additive, as a polymeric stabilizing and protecting agent for AuNPs is elucidated. The surface modification of Au-HMP nanoparticles was carried out using polyethylene glycol and transferrin to produce molecular probes for possible clinical applications. In vitro cell viability studies performed using as-synthesized Au-HMP nanoparticles and their surface-modified counterparts reveal the biocompatibility of the nanoparticles. The transferrin-conjugated nanoparticles have significantly higher cellular uptake in J5 cells (liver cancer cells) than control cells (oral mucosa fibroblast cells), as determined by inductively coupled plasma mass spectrometry. This study demonstrates the possibility of using an inexpensive and non-toxic food additive, HMP, as a stabilizer in the large-scale generation of biocompatible and monodispersed AuNPs, which may have future diagnostic and therapeutic applications.