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71.
Powell–Sabin B‐splines and unstructured standard T‐splines for the solution of the Kirchhoff–Love plate theory exploiting Bézier extraction 下载免费PDF全文
Stefan May Julien Vignollet René de Borst 《International journal for numerical methods in engineering》2016,107(3):205-233
The equations that govern Kirchhoff–Love plate theory are solved using quadratic Powell–Sabin B‐splines and unstructured standard T‐splines. Bézier extraction is exploited to make the formulation computationally efficient. Because quadratic Powell–Sabin B‐splines result in ‐continuous shape functions, they are of sufficiently high continuity to capture Kirchhoff–Love plate theory when cast in a weak form. Unlike non‐uniform rational B‐splines (NURBS), which are commonly used in isogeometric analysis, Powell–Sabin B‐splines do not necessarily capture the geometry exactly. However, the fact that they are defined on triangles instead of on quadrilaterals increases their flexibility in meshing and can make them competitive with respect to NURBS, as no bending strip method for joined NURBS patches is needed. This paper further illustrates how unstructured T‐splines can be modified such that they are ‐continuous around extraordinary points, and that the blending functions fulfil the partition of unity property. The performance of quadratic NURBS, unstructured T‐splines, Powell–Sabin B‐splines and NURBS‐to‐NURPS (non‐uniform rational Powell–Sabin B‐splines, which are obtained by a transformation from a NURBS patch) is compared in a study of a circular plate. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
72.
Cássia A. Glasser Marta M. D. C. Vila Júlio C. Pereira Marco V. Chaud José M. Oliveira Júnior Matthieu Tubino 《Drug development and industrial pharmacy》2016,42(12):1990-2000
The aqueous-core enclosed in lipid nanoballoons integrating multiple emulsions of the type water-in-oil-in-water mimic, at least in theory, the environment within viable cells, thus being suitable for housing hydrophilic protein entities such as bioactive proteins, peptides and bacteriophage particles. This study reports a complete physicochemical characterization of optimized biomimetic aqueous-core lipid nanoballoons housing hydrophilic (BSA) protein entities, evolved from a statistical 23×31 factorial design study (three variables at two levels and one variable at three levels) that was the subject of the first paper of a series of three, aiming at complete stabilization of the three-dimensional structure of protein entities attempted via housing the said molecular entities within biomimetic aqueous-core lipid nanoballoons integrating a multiple (W/O/W) emulsion. The statistical factorial design followed led to the production of an optimum W/O/W multiple emulsion possessing quite homogeneous particles with an average hydrodynamic size of (186.2?±?2.6) nm and average Zeta potential of (?36.5?±?0.9) mV, and exhibiting a polydispersity index of 0.206?±?0.014. Additionally, the results obtained for the diffusion coefficient of the lipid nanoballoons integrating the optimized W/O/W multiple emulsion were comparable and of the same order of magnitude (10?12 m2 s?1) as those published by other authors since, typically, diffusion coefficients for molecules range from 10?10 to 10?7 m2 s?1, but diffusion coefficients for nanoparticles are typically of the order of magnitude of 10?12 m2 s?1. 相似文献
73.
Minimum Setup Minimum Aberration Two‐level Split‐plot Type Designs for Physical Prototype Testing 下载免费PDF全文
Linda Lee Ho Carla A. Vivacqua André Luís Santos de Pinho 《Quality and Reliability Engineering International》2016,32(3):1007-1020
Although new technologies allow for less effort in prototyping, physical testing still remains an important step in the product development cycle. Well‐planned experiments are useful to guide the decision‐making process. During the design of an experiment, one of the challenges is to balance limited resources and system constraints to obtain useful information. It is common that prototypes are composed of several parts, with some parts more difficult to assemble than others. And, usually, there is only one piece available of each part type and a large number of different setups. Under these conditions, designs with randomization restrictions become attractive approaches. Considering this scenario, a new and additional criterion, minimum setup, to construct split‐plot type designs is presented. Designs with the minimum number of setups of the more difficult parts, which are especially useful for screening purposes in physical prototype testing, are discussed. The use of the proposed criterion combined with minimum aberration for selecting a regular design is shown through a real application in testing car prototypes. As a tool to practitioners, catalogs of selected 32‐run minimum setup minimum aberration split‐split‐plot and split‐split‐split‐plot designs are presented. More complete catalogs are available as Supporting information. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
74.
On the Structure of Amorphous Mesoporous Silica Nanoparticles by Aberration‐Corrected STEM 下载免费PDF全文
Sebastian Calderon V Tânia Ribeiro José Paulo S. Farinha Carlos Baleizão Paulo J. Ferreira 《Small (Weinheim an der Bergstrasse, Germany)》2018,14(40)
Mesoporous silica materials have demonstrated a vast spectrum of applications, stimulating an intensive field of study due to their potential use as nanocarriers. Nonetheless, when produced at the nanoscale, their structural characterization is hindered due to the re‐arrangement of the pores. To address this issue, this work combines molecular dynamics simulations with electron microscopy computer simulations and experimental results to provide an insight into the structure of amorphous mesoporous silica nanoparticles. The amorphous silica model is prepared using a simple melt‐quench molecular dynamics method, while the reconstruction of the mesoporous nanoparticles is carried out using a methodology to avoid false symmetry in the final model. Simulated scanning transmission electron microscopy images are compared with experimental images, revealing the existence of structural domains, created by the misalignment of the pores to compensate the surface tension of these spherical nanoparticles. 相似文献
75.
Mónica Giménez‐Marqués Elena Bellido Thomas Berthelot Teresa Simón‐Yarza Tania Hidalgo Rosana Simón‐Vázquez África González‐Fernández José Avila Maria Carmen Asensio Ruxandra Gref Patrick Couvreur Christian Serre Patricia Horcajada 《Small (Weinheim an der Bergstrasse, Germany)》2018,14(40)
Controlling the outer surface of nanometric metal–organic frameworks (nanoMOFs) and further understanding the in vivo effect of the coated material are crucial for the convenient biomedical applications of MOFs. However, in most studies, the surface modification protocol is often associated with significant toxicity and/or lack of selectivity. As an alternative, how the highly selective and general grafting GraftFast method leads, through a green and simple process, to the successful attachment of multifunctional biopolymers (polyethylene glycol (PEG) and hyaluronic acid) on the external surface of nanoMOFs is reported. In particular, effectively PEGylated iron trimesate MIL‐100(Fe) nanoparticles (NPs) exhibit suitable grafting stability and superior chemical and colloidal stability in different biofluids, while conserving full porosity and allowing the adsorption of bioactive molecules (cosmetic and antitumor agents). Furthermore, the nature of the MOF–PEG interaction is deeply investigated using high‐resolution soft X‐ray spectroscopy. Finally, a cell penetration study using the radio‐labeled antitumor agent gemcitabine monophosphate (3H‐GMP)‐loaded MIL‐100(Fe)@PEG NPs shows reduced macrophage phagocytosis, confirming a significant in vitro PEG furtiveness. 相似文献
76.
Christian Wolf Martin Prechtl René Bauer Michael Dinkel Fabian Beck Leopold Franz Viktor Neumeyer 《真空研究与实践》2023,35(1):35-39
To mark our anniversary, we are presenting articles that have been particularly appreciated by readers of our online edition once again in print. Here: 3D-Printing for High Vacuum Applications 3D printing technology has made the leap from a home-based private practice to industrial manufacturing. Due to the increasing reliability of printers and increasing material diversity, especially in the metal sector, double-digit percentage growth rates are possible in the coming years. This thesis deals with the manufacture of parts made by 3D printing for high vacuum application. Different components are printed and examined for their vacuum compatibility. As shown furthermore, conventionally made standard components can be vacuum sealed to printed parts, which enables cost-effective production of more complex components, such as e.g. a vacuum chamber allows. In addition, functional components can already be realized in the manufacturing process. The integration of a system of flow channels directly into the wall of a chamber is just one example. Thus, such a chamber can be heated during evacuation and effectively cool in later operation. 相似文献
77.
To meet the requirements of comprehensively characterizing the morphology of thin films and substrates, a suitable combination of different measuring techniques should be chosen, i.e., a nonoptical surface profile measurement should be used together with optical analysis. It is demonstrated on selected examples of fluoride and oxide films that the use of atomic force microscopy and light scattering fulfills the demand of appropriate quantitative characterization over a sufficiently large range of bandwidths. 相似文献
78.
Diego Castaño José Patricio Díaz Varela Antoni Torrens 《Soft Computing - A Fusion of Foundations, Methodologies and Applications》2011,15(7):1449-1455
In this paper, we show that free algebras in the variety of residuated lattices and some of its subvarieties are directly
indecomposable and show, as a consequence, the direct indecomposability of free algebras for some classes of their bounded
implicative subreducts. 相似文献
79.
The localization of the components of an object near to a device before obtaining the real interaction is usually determined by means of a proximity measurement to the device of the object’s features. In order to do this efficiently, hierarchical decompositions are used, so that the features of the objects are classified into several types of cells, usually rectangular.In this paper we propose a solution based on the classification of a set of points situated on the device in a little-known spatial decomposition named tetra-tree. Using this type of spatial decomposition gives us several quantitative and qualitative properties that allow us a more realistic and intuitive visual interaction, as well as the possibility of selecting inaccessible components. These features could be used in virtual sculpting or accessibility tasks.In order to show these properties we have compared an interaction system based on tetra-trees to one based on octrees. 相似文献
80.
André Maués Brabo Pereira Marcos Aurélio Marques Noronha 《Engineering with Computers》2010,26(1):35-47
Most post-processors for boundary element (BE) analysis use an auxiliary domain mesh to display domain results, working against
the profitable modelling process of a pure boundary discretization. This paper introduces a novel visualization technique
which preserves the basic properties of the boundary element methods. The proposed algorithm does not require any domain discretization
and is based on the direct and automatic identification of isolines. Another critical aspect of the visualization of domain
results in BE analysis is the effort required to evaluate results in interior points. In order to tackle this issue, the present
article also provides a comparison between the performance of two different BE formulations (conventional and hybrid). In
addition, this paper presents an overview of the most common post-processing and visualization techniques in BE analysis,
such as the classical algorithms of scan line and the interpolation over a domain discretization. The results presented herein
show that the proposed algorithm offers a very high performance compared with other visualization procedures. 相似文献