Electrospun PELCL membranes loaded with QK peptide for enhancement of vascular endothelial cell growth

One of the major challenges in tissue engineering of small-diameter vascular grafts is to inhibit intimal hyperplasia and keep long-term patency after implantation. Rapid endothelialization of the grafts could be an effective approach. In this study, QK, a peptide mimicking vascular endothelial growth factor, was selected as the bioactive substrate and loaded in electrospun membranes for enhancement of vascular endothelial cell growth. In detail, QK peptide was firstly introduced with poly(ethylene glycol) diacrylate into a thiolated chitosan solution that could transfer into hydrogel. Then, suspensions or emulsions of poly(ethylene glycol)-b-poly(l-lactide-co-ε-caprolactone) (PELCL) containing QK peptide (with or without chitosan hydrogel) were electrospun into fibrous membranes. For comparison, the electrospun PELCL membrane without QK was also fabricated. Results of release behaviors showed that the electrospun membranes, especially that contained chitosan hydrogel prepared by suspension electrospinning, could successfully encapsulate QK peptide and maintain its secondary structure after released. In vitro cell culture studies exhibited that the release of QK peptide could accelerate the proliferation of vascular endothelial cells in the 9 days. It was suggested that the electrospun PELCL membranes loaded with QK peptide might have potential applications in vascular tissue engineering.     

氧化镧/聚丙烯防X射线复合纤维的制备及性能表征

先采用熔融纺丝方法制备了不同氧化镧含量的氧化镧/聚丙烯复合纤维,然后采用对二甲苯在相同处理时间(1 h)不同温度(105~109℃)下溶解复合纤维中的部分聚丙烯基体以提高纤维中氧化镧含量,并对处理过后的纤维进行扫描电镜、X射线屏蔽性能等测试。此外,采用硅烷偶联剂改性氧化镧,通过熔融纺丝法制备了表面活性氧化镧/聚丙烯复合纤维,并对其作了差示扫描量热分析、扫描电镜、力学测试等性能表征。实验结果表明,随未改性氧化镧添加量增加,纤维力学性能下降,玻璃化转变温度向低温方向移动,纤维热稳定提高;有机改性可改善氧化镧在聚丙烯中的分散,提高纤维的力学性能,纤维玻璃化转变温度较纯聚丙烯纤维升高;用对二甲苯在107℃处理1h所获取的复合纤维中氧化镧含量最高,X射线屏蔽性能最优。     

Ti/Nb作中间层脉冲加压扩散连接TiC金属陶瓷与不锈钢

用Ti/Nb作中间层,在温度890℃、时间4~12min、脉冲压力2~10MPa、频率f=0.5Hz、恒压10MPa下,对TiC金属陶瓷和304不锈钢(304SS)进行脉冲加压与恒压扩散焊,获得了牢固的固相扩散焊接头。通过扫描电镜SEM、能谱EDS、X射线衍射XRD与剪切性能测试,对接头的显微组织、界面产物与强度进行分析。结果显示:两种接头的界面物相相似,主要有σ相,(β-Ti,Nb)与α+β-Ti固溶体。连接时间10min时,恒压下的TiC/304SS接头抗剪强度为55.6MPa,而脉冲加压下的接头抗剪强度达110MPa。恒压下接头断裂方式为TiC陶瓷断裂,而脉冲压力下接头断裂方式为TiC陶瓷与界面产物间交替进行的混合断裂。     

自制地温转接板引起测量误差偏移量的测定

本文通过实验方式,建立了测定自制地温转接板引起测量误差偏移量的测量模型,通过实验数据,计算出了自制地温转接板引起的被校传感器测量误差偏移量。     

60°镜面光泽测量值不确定度的评定

本文采用光泽度仪对漆膜的60°镜面光泽进行了测量,对产生测量不确定度的因素进行了分析,并对其A类和B类不确定度进行了分别评定,最终获得其测量结果的扩展不确定度。     

A thermovisco-hyperelastic constitutive model of HTPB propellant with damage at intermediate strain rates

The uniaxial compressive tests at different temperatures (223–298 K) and strain rates (\(0.40\mbox{--}63~\mbox{s}^{-1}\)) are reported to study the properties of hydroxyl-terminated polybutadiene (HTPB) propellant at intermediate strain rates, using a new INSTRON testing machine. The experimental results indicate that the compressive properties (mechanical properties and damage) of HTPB propellant are remarkably affected by temperature and strain rate and display significant nonlinear material behaviors at large strains under all the test conditions. Continuously decreasing temperature and increasing strain rate, the characteristics of stress-strain curves and damage for HTPB propellant are more complex and are significantly different from that at room temperature or at lower strain rates. A new constitutive model was developed to describe the compressive behaviors of HTPB propellant at room temperature and intermediate strain rates by simply coupling the effect of strain rate into the conventional hyperelastic model. Based on the compressive behaviors of HTPB propellant and the nonlinear viscoelastic constitutive theories, a new thermovisco-hyperelastic constitutive model with damage was proposed to predict the stress responses of the propellant at low temperatures and intermediate strain rates. In this new model, the damage is related to the viscoelastic properties of the propellant. Meanwhile, the effect of temperature on the hyperelastic properties, viscoelastic properties and damage are all considered by the macroscopical method. The constitutive parameters in the proposed constitutive models were identified by the genetic algorithm (GA)-based optimization method. By comparing the predicted and experimental results, it can be found that the developed constitutive models can correctly describe the uniaxial compressive behaviors of HTPB propellant at intermediate strain rates and different temperatures.     

Distinguishable Detection of Ultraviolet,Visible, and Infrared Spectrum with High‐Responsivity Perovskite‐Based Flexible Photosensors

Distinguishable detection of the ultraviolet, visible, and infrared spectrum is promising and significant for the super visual system of artificial intelligences. However, it is challenging to provide a photosensor with such broad spectral response ability. In this work, the ultraviolet, visible, and infrared spectrum is distinguished by developing serial photosensors based on perovskite/carbon nanotube hybrids. Oraganolead halide perovskites (CH₃NH₃PbX₃) possess remarkable optoelectronic properties and tunable optical band gaps by changing the halogens, and integration with single‐walled carbon nanotubes can further improve their photoresponsivities. The CH₃NH₃PbCl₃‐based photosensor shows a responsivity up to 10⁵ A W^?1 to ultraviolet and no obvious response to visible light, which is superior to that of most ultraviolet sensors. The CH₃NH₃PbBr₃‐based photosensor exhibits a high responsivity to visible light. Serial devices of the two hybrid photosensors with comparable electric and sensory performances can distinguish the spectrum of ultraviolet, visible, and infrared even with varying light intensities. The photosensors also demonstrate excellent mechanical flexibility and bending stability. By taking full advantages of the oraganolead halide perovskites, this work provides flexible high‐responsivity photosensors specialized for ultraviolet, and gives a simple strategy for distinguishable detection of ultraviolet, visible, and infrared spectrum based on the serial flexible photosensors.