Controlled radical polymerization with polyolefin macroinitiator: a convenient and versatile approach to polyolefin-based block and graft copolymers

This paper introduces the new synthetic methodology of polyolefin-based block and graft copolymers with polar segments [e.g., polystyrene and poly(meth)acrylates]. Various brominated polyolefins were prepared by bromination of polyolefins with N-bromosuccinimide. The resulting brominated polyolefins were able to initiate the controlled radical polymerization of polar monomers, such as methyl methacrylate, ethyl acrylate, t-butyl acrylate, styrene and 2-(dimethylamino)ethyl acrylate, using a CuBr/N,N,N′,N″,N″-pentamethyldiethylenetriamine catalyst system, leading to a variety of polyolefin-based copolymers with a different content of the corresponding polar segment. Because of the accessible synthesis of polyolefin macroinitiators, this synthetic methodology is expected to result in the preparation of a wide range of polyolefin-based block and graft copolymers.     

Flexible magnetic copolymer films with high decomposition temperature and stable dielectric properties

Two novel kinds of flexible magnetic copolymer films were prepared via copolymerization using magnetic ferrocenyl prepolymer (MFP) and poly(arylene ether nitrile)s with bisphthalonitrile functional group. Two types of poly(arylene ether nitrile)s with bisphthalonitrile functional group were used and two series of flexible magnetic copolymer film with different structure were obtained. The magnetic properties of copolymer films indicated that the films were soft magnetic. Moreover, it was also concluded that the magnetic properties of magnetic films prepared from phthalonitrile terminated poly(arylene ether nitrile)s were higher than that of magnetic films prepared from poly(arylene ether nitrile)s with pendant phthalonitriles at the same content of MFP. The results of thermogravimetry showed that the all of the copolymer films possessed high decomposition temperature. Like the magnetism, the dielectric constant and dielectric loss of films obtained from phthalonitrile terminated poly(arylene ether nitrile)s were also higher than that of films obtained from poly(arylene ether nitrile)s with pendant phthalonitriles.     

职务犯罪案件逮捕决定权配置改革审视

介绍了检察院直接受理侦查案件由上一级检察院审查逮捕的法理依据,分析了职务犯罪案件决定逮捕权上提一级后将面临的问题,提出了克服问题的措施建议。     

Biochip with integrated pumps for plug-based sequential exchange of solutions

A novel method for exchanging solutions used in biochemical analyses and a device to carry out the exchange are proposed. An array of plugs formed using six injectors was transported in a microflow channel using a main pump located at one end of the main flow channel. The injectors and main pump were operated on the basis of the change in volume caused by the electrolysis of water. Bubbles were produced from working electrodes; these bubbles caused a diaphragm placed below the injectors to inflate and occlude the inlet of the solution reservoir. Increase in the number of bubbles caused the reservoir to inject the solution into the main flow channel in the form of a plug. Each plug was individually transported downstream to the sensing area by the main pump, which was operated in a similar manner to the injector. The device was used for the detection of a tumor marker, α-fetoprotein (AFP). Plugs of necessary solutions were individually transported to the sensing area with immobilized primary antibodies to allow antigen–antibody binding, cleaning, and detection. The fluorescence intensity from the antibodies showed clear dependence on the concentration of AFP. The immobilization of antibodies could also be carried out on-chip.     

Switching of output coupling in a grating coupler by diffraction transition to the distributed Bragg reflector regime

In a proposed switching grating coupler (SGC), the grating period Lambda is chosen so that the SGC converts from a first-order grating coupler to a third-order distributed Bragg reflector by means of a small change in the guided mode index. The principle for switching the radiated wave power and the effective aperture of the SGC were experimentally confirmed by use of the thermo-optic effect of a polymer waveguide. The extinction of the peak intensity of the wave radiated by the SGC and collected by an external lens was measured to be 5 dB with a temperature change of 10 degrees.     

IPC-80亚、跨、超音速风洞弹丸及飞行器试验测试系统

本文主要介绍亚、跨、超音速风洞基本结构及气动原理,新配置的IPC-80测试系统。论述了弹丸及飞行器气动试验模拟信号处理、变换采样、数字量取真、模型迎角和阀位循环码读取方法,对标模动校作了测试精度考核。     

Heterogeneous pattern of gene expression in cloned cell lines established from a rat transplantable osteosarcoma lung metastatic nodule

We have established three cloned cell lines (COS1NR, COS2NR and COS4NR) from the lung metastatic nodule of a highly metastatic variant of rat transplantable osteosarcoma, C-SLM. All three clones shared the same morphological characteristics and tumorigenicity, but their growth rates in vitro and metastatic ability in vivo differed from each other. Single-strand conformation polymorphism (SSCP) analysis revealed all three clones to have the same p53 gene mutation and parent C-SLM tumor. On the other hand, Northern blot analysis showed a different pattern of expression for the genes, c-fos, c-jun, c-Ha-ras, transin (rat stromelysin), bone Gla protein (osteocalsin) and nm23/NDP kinase. These results indicate the presence of a heterogeneous cell population in terms of the different pattern of gene expression in a lung metastatic nodule of rat osteosarcoma and the present newly established cell lines will be useful for further investigation of the biological behavior of osteosarcomas.     

Human spinal arachnoid villi and granulations

A commercially available recording of Northwestern University Auditory Test No. 6 (N.U. No. 6) produced by Auditec of St. Louis was evaluated in a series of four studies. Interlist equivalence of this version was initially investigated, and then normative intelligibility functions were developed using listerners with normal hearing. Intelligibility functions for the original version of N.U. No. 6. prepared by Northwestern University, were then derived, concurrently with functions of the Auditec version, using (1) a group of listeners with normal hearing; and (2) a group with sensorineural hearing loss. The results demonstrated good interlist equivalence for the Auditec version of N.U. No. 6. The comparative intelligibility functions for the Auditec and Northwestern versions of N.U. No 6 furthermore indicated a difference between the two recordings, but it was concluded that for clinical purposes the two versions may be considered equivalent.     

Factors affecting the oxidative activity of laccase towards biphenyl derivatives in homogeneous aqueous-organic systems

Catalytic oxidation of biphenyl derivatives was investigated using laccase in a homogeneous aqueous-organic system. A thermostable laccase from Trametes sp. showed the highest catalytic activity for the oxidation of 4-hydroxybiphenyl (4-HB) at a reaction temperature of 60 degrees C when dimethylsulfoxide (DMSO) was employed as a co-solvent. Furthermore, the catalytic performance was successfully enhanced by the incorporation of a laccase mediator system (LMS) into the aqueous-DMSO media. The catalytic performance strongly depended on the type of mediator, and the highest activity was observed with 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) as mediator, suggesting the importance of the selection of a suitable mediator. It was verified that this mediator system is applicable to the oxidation of several biphenyl derivatives with hydroxyl groups.