Rate of accumulation of Luxol Fast Blue staining material and mitochondrial ATP synthase subunit 9 in motor neuron degeneration mice

The rate of accumulation of Luxol Fast Blue staining material in the hippocampus of motor neuron degeneration (mnd/mnd) mice, a model of Batten Disease, was quantitated. Stained material increased linearly up to 8 months of age. A quantitative immunoassay was used to measure levels of mitochondrial ATP synthase subunit 9 in brain and liver of mnd/mnd mice. Levels of subunit 9 increased progressively throughout the lifespan of mnd/mnd mice reaching levels approximately 5-fold higher than in control animals. The rate of accumulation of subunit 9 is not consistent with any simple complete or partial degradation defect that is constant throughout the animal's life. Two more complicated models are discussed which are consistent with the observed accumulation rate of subunit 9.     

Do places matter? Socioeconomic disadvantage and behavioral problems of children in Canada.

This study evaluated the influence of neighborhoods and socioeconomic disadvantage on behavioral problems rated by parents and teachers in a nationally representative sample of children ages 4 to 11 yrs living in Canada. Between-neighborhood variation accounted for 7.6% and 6.6% of parent and teacher ratings, respectively. About 25.0% of this neighborhood variation could be explained by socioeconomic variables evenly divided between neighborhood and family-level measures. Family socioeconomic status, lone-parent family status, and percentage of lone parents in neighborhoods were strong, reliable predictors of behavioral problems. Ratings were contextualized: Fewer behavioral problems were assessed in children from well-off families living in disadvantaged neighborhoods, whereas more problems were assessed in children from poor families living in advantaged neighborhoods. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Control from the actor's perspective.

Examines a situation that embodies the entire spectrum of perceived control ranging from extreme helplessness to extreme domination. The authors consider sexual trauma from the perspective of the victim. From the actor's perspective, an important distinction is made between choice and prediction. This shows that, even in situations of apparent helplessness, perceived control may be legitimate from the actor's perspective. From this perspective, current theoretical frameworks on control may have distorted the actor's reality. It is suggested that future research on perceived control should be guided by the actor's perspective. (French abstract) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Evaluating Self-Generated Information: Anterior Prefrontal Contributions to Human Cognition.

The anterior or rostrolateral prefrontal cortex (RLPFC) is frequently recruited during complex cognitive tasks across a wide range of domains, including reasoning, long-term memory retrieval, and working memory. The authors report an event-related functional MRI study, indicating that the RLPFC is specifically involved in the evaluation of internally generated information--or information that cannot be readily perceived from the external environment but has to be inferred or self-generated. The findings are consistent with a hierarchical model of lateral prefrontal organization, with RLPFC contributing only at the highest orders of cognitive transformations. This characterization of RLPFC function may help explain seemingly disparate findings across multiple cognitive domains and could provide a unified account of this region's contribution to human cognition. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Counterfactual Thinking and the First Instinct Fallacy.

Most people believe that they should avoid changing their answer when taking multiple-choice tests. Virtually all research on this topic, however, has suggested that this strategy is ill-founded: Most answer changes are from incorrect to correct, and people who change their answers usually improve their test scores. Why do people believe in this strategy if the data so strongly refute it? The authors argue that the belief is in part a product of counterfactual thinking. Changing an answer when one should have stuck with one's original answer leads to more "if only . . ." self-recriminations than does sticking with one's first instinct when one should have switched. As a consequence, instances of the former are more memorable than instances of the latter. This differential availability provides individuals with compelling (albeit illusory) personal evidence for the wisdom of always following their 1st instinct, with suboptimal test scores the result. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Persistence of Preference for a Flavor Presented in Simultaneous Compound With Sucrose.

Rats exposed to a simultaneous compound of a flavor and sucrose subsequently exhibited a preference for the flavor over water. This preference persisted across repeated testing even though the flavor was presented in the absence of sucrose. The preference did, however, extinguish if the rats were hungry when trained or tested, or if they had been reexposed to sucrose between training and test. Though failing to extinguish the preference, presentation of the flavor outside the compound protected it from the effects of sucrose devaluation, indicating that these presentations extinguished the within-compound association between the flavor and sucrose. The authors conclude that the hedonic reaction elicited by sucrose imbues the flavor with the same hedonic properties, and these properties maintain the preference independently of the flavor-sucrose association. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Improved signal averaging performance in a weighing system

Translated from Izmeritel'naya Tekhnika, No. 5, pp. 22–23, May, 1988.     

Adding compression to a full-text retrieval system

We describe the implementation of a data compression scheme as an integral and transparent layer within a full-text retrieval system. Using a semi-static word-based compression model, the space needed to store the text is under 30 per cent of the original requirement. The model is used in conjunction with canonical Huffman coding and together these two paradigms provide fast decompression. Experiments with 500 Mb of newspaper articles show that in full-text retrieval environments compression not only saves space, it can also yield faster query processing - a win-win situation.