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11.
An experimental investigation of the steady-state rates of heat transfer from an array of vertical rectangular 3 mm thick fins, extending 60 mm perpendicularly out of a 250 mm high vertical rectangular base, is reported. For base temperatures between room temperature (~ 15°C) and 100°C, the optimal separation of the parallel fins, corresponding to the maximum rate of heat loss, is 10 ± 1 mm.  相似文献   
12.
Peptide growth factors play a role in the maintenance of normal prostatic growth and differentiation (Fig. 2). It seems likely that the androgen sensitivity of human prostate is mediated by the production of peptide growth factors from stromal cells which act as the direct intermediate of androgen action on epithelial cells. TGF-beta 1 inhibition of epithelial cells is opposed by the stimulatory action of EGF, IGF and FGFs to maintain an equilibrium of epithelial cell numbers. The indirect mitogenic action of androgens appear to act by down-regulation of TGF-beta 1 and possibly EGF receptors. There is also interaction with the effects of IGF-II, produced by prostatic stromal cells and acting on epithelial cells to increase proliferation. The growth of normal prostatic fibroblasts is under the control of bFGF and TGF-beta 1. However, although our understanding of the actions of these growth factors in the normal prostate has improved over the last decade, their role in the development and maintenance of prostate cancer is less clearly defined. TGF-beta 1, classically considered to be inhibitory for epithelial cells, may be up-regulated in prostatic tumours, stimulating growth. Alternatively, autocrine production of such growth factors by tumour cells may lead to loss of inhibitory effects from exogenous TGF-beta 1, a mechanism also witnessed with TGF-alpha and bFGF. The role of EGF in the development of prostate cancer is confusing because results from the use of different cell types and experimental conditions is contradictory. It may be that a switch in the production of the predominant EGFr ligand from EGF to TGF-alpha is an important feature in the development and maintenance of the malignant phenotype. The presence of TGF-alpha autocrine loops has been shown clearly in some tumour cell lines. This switch in the production of a particular ligand may also be a feature of IGFs in prostate cancer. IGF-II may be replaced by IGF-I during malignant progression, both of which are able to act via the type 1 receptor. This change in IGF expression appears to be accompanied by altered expression of the IGF-BP2, with less detectable within prostatic tissues but elevated serum levels [58]. Basic FGF is normally produced by prostatic fibroblasts but is also produced by some prostatic cancer cell lines [64]. However, as with all growth factors, the expression of the bFGF protein and its receptor is dependent on the cell line examined. The autocrine and paracrine control of normal and abnormal prostatic growth by growth factors is important in determining their role in the development and maintenance of prostate cancer. Better understanding of such mechanisms is essential for the development of novel therapeutic strategies in the control and treatment of prostate cancer.  相似文献   
13.
A method of analysing solids downflow through standpipe and slide valve in the moving bed mode is presented. The method is based on combining Yoon and Kunii equations for moving-bed flow with a proposed modified orifice equation for gas—solid flow. The analysis correctly predicts the observed trend of the effects of gas injection into the standpipe. It also provides quantitative prediction of the conditions for transition from moving-bed flow to dense phase fluidized solids flow and to lean phase “streaming flow”. The latter flow pattern refers to solids streaming down a tube at high voidage typified by the discharge of solid down a tube with no constriction at the lower end of the tube. Further work is required to test the general applicability of the present analysis and to extend the analysis to yield a generalized quantitative flow regime diagram for downflow of solids in a pipe.  相似文献   
14.
The metallo-organic solution deposition (MOSD or sol-gel) technique can be used for preparing lead zirconate titanate (PZT) ceramics with a wide range of compositions and crystal structures for electrooptical applications. Film morphology is affected by the stoichiometry of the film, hydrolysis and polymerization of the sol-gel solution, and thermal treatment of the deposited material. The lattice parameter decreases with the amount of titanium in the PZT, in agreement with ceramic data. A slight initial excess of lead in the coating solution is found to improve film morphology. Unlike traditional powder ceramic processing techniques, MOSD permits the growth of small uniform grains that are conducive to achieving consistent electronic and optical properties. Results show that the properties of films prepared by the MOSD process can be tailored to meet the needs of device applications.  相似文献   
15.
Data races hamper parallel programming and threaten the reliability of future software. This paper proposes the data race prevention scheme View-Oriented Data race Prevention (VODAP), which can prevent data races in the View-Oriented Parallel Programming (VOPP) model. VOPP is a novel shared-memory data-centric parallel programming model, which uses views to bundle mutual exclusion with data access. We have implemented the data race prevention scheme with a memory protection mechanism. Experimental results show that the extra overhead of memory protection is trivial in our applications. The performance is evaluated and compared with modern programming models such as OpenMP and Cilk.  相似文献   
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17.
Abstract Teaching with the world-wide web is becoming a common practice in modern education. The web serves two main interrelated functions, namely, retrieval and publication of information. To enhance learning and motivation, the student-as-teacher (SAT) principle was adopted in the study reported in this paper. Students were given the role of teacher of high school students and the general public about the subject matter they learned on a course. To achieve this goal, the students created educational web sites featuring two selected psychological professions. Being the major assignment for the course, the web sites created by students received higher scores than the assignments of their peers who learned the same materials through traditional pedagogical approaches. Course evaluation confirmed that the web implementation of the SAT principle enhanced learning, increased motivation and provided a transfer-able skill, without compromising accomplishment of major course goals.  相似文献   
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19.
With the introduction of low‐powered pico/femto‐base stations and relay nodes into the macro‐cell, recent heterogeneous networks provide an attractive approach for future wireless communication. Although it may achieve better coverage and higher capacity, several problems remain unsolved before practical deployment. For example, how to select the proper cell from neighbor low‐powered cells and then occupy the radio resource without interference on macro‐users is both important and challenging, especially for rigorous multimedia applications. The traditional cell access algorithms and quality‐control parameters such as delay or throughput no longer suit well in this complex environment. An effective approach should be pursued. In this paper, we investigate this interesting cell association problem and propose a complete green resolution on the basis of thorough discussions about the multimedia transmission under these concerns. Cognitive radio is introduced to share spectrum between macro‐cell and low‐powered cells while securing the transmission of authorized macro‐users. We also bring forth the concept of ‘interference balance’ to better manage the overall interference and energy consumption in the network. Restless bandit model is formulated on the basis of channel state, data rate, interference control, and the carefully chosen intra‐refreshing rate for multimedia traffic. Then the cell association scheme is designed to be efficient and practical because of the simple index property of our model output. Simulation results have proven the performance of our proposed resolution compared with existing algorithms on interference constraint, multimedia distortion, and overall network energy consumption balance. Copyright © 2013 John Wiley & Sons, Ltd.  相似文献   
20.
Fracture mechanism is pertinent to minimize the catastrophic failures and optimize the structural design. An exact treatment on the electromagnetic permeable crack problems in a magnetoelectroelastic medium is presented by establishing a Hamiltonian system in terms of the symplectic eigenfunctions. The coefficients of the series are determined from the lateral boundary conditions at the crack surfaces and the outer boundary conditions along the geometric domain. Analytical formulations of intensity factors and distributions of dual variables are obtained by the symplectic expansion method. The various intensity factors are directly related to the first few terms of the non-zero eigenvalue solutions.  相似文献   
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