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81.
Tzong‐Ru Tsai Hon Keung Tony Ng Hoang Pham Yuhlong Lio Jyun‐You Chiang 《Quality and Reliability Engineering International》2019,35(7):2297-2313
Type‐I interval‐censoring scheme only documents the number of failed units within two prespecified consecutive exam times at the larger time point after putting all units on test at the initial time schedule. It is challenging to use the collected information from type‐I interval‐censoring scheme to evaluate the reliability of unit when not all admitted units are operated or tested at the same initial time and a majority of units are randomly selected to replace the failed test units at unrecorded time points. Moreover, the lifetime distribution of all pooled units from dual resources usually follows a mixture distribution. To overcome these two problems, a two‐stage inference process that consists of a data‐cleaning step and a parameter estimation step via either Markov chain Monte Carlo (MCMC) algorithm or profile likelihood method is proposed based on the contaminated type‐I interval‐censored sample from a mixture distribution with unknown proportion. An extensive simulation study is conducted under the mixture smallest extreme value distributions to evaluate the performance of the proposed method for a case study. Finally, the proposed methods are applied to the mixture lifetime distribution modeling of video graphics array adapters for the support of reliability decision. 相似文献
82.
Police Vishnuvardhan Reddy Pottabathula Srinivas Manne Annapurna Suresh Bhargava Jorg Wagler Nedaossadat Mirzadeh Mannepalli Lakshmi Kantam 《Advanced Synthesis u0026amp; Catalysis》2013,355(4):705-710
We herein report the design and development of a carboxyamido/carbene ligand and its Pd‐complex for the decarboxylative coupling of alkynylcarboxylic acids with aryl and heteroaryl halides to afford arylalkynes. 相似文献
83.
Wai Keung Li 《时间序列分析杂志》2011,32(6):639-646
The classical autocorrelation function may not be an effective and informative means in revealing the dependence features of a binary time series {yt}. Recently, the autopersistence functions defined as APF0(k) = P(yt+k = 1 | yt = 0) and APF1(k) = P(yt+k = 1 | yt = 1), k = 1, 2,…, have been proposed as alternatives to the autocorrelation function for binary time series. In this article we consider the theoretical autopersistence functions and their natural sample analogues, the autopersistence graphs, under a binary autoregressive model framework. Some properties of the autopersistence functions and the asymptotic properties of the autopersistence graphs are discussed. The results have potential application in the modelling of binary time series. 相似文献
84.
Navya Manne Hemant K. S. Yadav S. Hemanth Kumar Tashi Chojjom Khom N. Sankeerth Kumar 《应用聚合物科学杂志》2014,131(2)
Liposomes of antiviral drug(acyclovir) prepared by rotary evaporation method were incorporated into two bioadhesive polymers, carbopol and HPMC and freeze dried to obtain a unit dosage form. The liposomes, liposomal gels and freeze dried rods were evaluated for various parameters. TEM analysis showed the formation of unilamellar liposomes with a mean diameter ranging from 0.9 μm to 1.2 μm. As the cholesterol content increases from 0.5% to 2%w/w, the entrapment efficiency and vesicle size increased. Carbopol gels exhibited higher viscosity, spreadability, mucoadhesiveness than HPMC gels. The redipsersion of freeze dried forms in SVF was found to be slow and its ex‐vivo retention time was found to be 12 hrs while acyclovir gel retained only for 8.25 hrs. The tablet and gel released 96.93±0.15% acyclovir within 6 hrs and 92.31±0.31% by 8 hrs respectively while freeze dried forms could sustain the release upto 12 hrs. From the stability studies the optimum storage condition was found to be 4‐8°C. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014 , 131, 39804. 相似文献
85.
Nicole Dmochowska Valentina Milanova Ramesh Mukkamala Kwok Keung Chow Nguyen T. H. Pham Madduri Srinivasarao Lisa M. Ebert Timothy Stait-Gardner Hien Le Anil Shetty Melanie Nelson Philip S. Low Benjamin Thierry 《Small (Weinheim an der Bergstrasse, Germany)》2023,19(21):2204956
Accurate delineation of gross tumor volumes remains a barrier to radiotherapy dose escalation and boost dosing in the treatment of solid tumors, such as prostate cancer. Magnetic resonance imaging (MRI) of tumor targets has the power to enable focal dose boosting, particularly when combined with technological advances such as MRI-linear accelerator. Fibroblast activation protein (FAP) is overexpressed in stromal components of >90% of epithelial carcinomas. Herein, the authors compare targeted MRI of prostate specific membrane antigen (PSMA) with FAP in the delineation of orthotopic prostate tumors. Control, FAP, and PSMA-targeting iron oxide nanoparticles were prepared with modification of a lymphotropic MRI agent (FerroTrace, Ferronova). Mice with orthotopic LNCaP tumors underwent MRI 24 h after intravenous injection of nanoparticles. FAP and PSMA nanoparticles produced contrast enhancement on MRI when compared to control nanoparticles. FAP-targeted MRI increased the proportion of tumor contrast-enhancing black pixels by 13%, compared to PSMA. Analysis of changes in R2 values between healthy prostates and LNCaP tumors indicated an increase in contrast-enhancing pixels in the tumor border of 15% when targeting FAP, compared to PSMA. This study demonstrates the preclinical feasibility of PSMA and FAP-targeted MRI which can enable targeted image-guided focal therapy of localized prostate cancer. 相似文献
86.
This paper studies users' learning perception in a virtual titration experiment with differentiated instruction. We develop a virtual reality chemistry lab and use leap motion to detect users' hand gestures for operations. Users wear a head‐mounted display and use their bare hands to interact with virtual objects to perform a titration experiment. Our system implements a complete titration process and provides assistance tools for learning and operating virtual items. We report the essential ideas for building the system. We applied differentiated instruction to study the learning effectiveness of users under different learning intensities. Two groups of students with and without chemistry background participated in a user study. Our results indicated that the virtual reality chemistry lab could enhance and promote users' learning confidence under suitable learning intensities. 相似文献
87.
Ya‐Kun Wang Si‐Hua Li Sheng‐Fan Wu Chen‐Chao Huang Sarvendra Kumar Zuo‐Quan Jiang Man‐Keung Fung Liang‐Sheng Liao 《Advanced functional materials》2018,28(13)
Despite promising efficiency, the high fabrication cost due to the required high concentrations of noble metal based phosphors is still problematic for phosphorescent organic light‐emitting diodes (PhOLEDs). This situation becomes even serious considering some practical applications need high luminance, which in turn requires a higher concentration of emitters. A paradigm shift to circumvent these issues can be development of materials that are able to operate efficiently in very low concentrations ( < 1 wt%). Here, two thermally activated delayed fluorescence hosts ( OSTFPCN and OSTFPB ) with tilted spiro geometry, small singlet‐triplet splitting ( Δ E st), and effective resonance energy transfer are developed. Within expectation, record performances with a power efficiency of 63.6 lm W?1 and an external quantum efficiency (EQE) of 31.2% for the red phosphor Ir(MDQ)2(acac) (2.0 wt%) are achieved with OSTFPCN as host. Additionally, a high power efficiency around 58 lm W?1 is also gained even at an ultralow dopant concentration of 0.5 wt% for a OSTFPB based device. Mechanism studies demonstrate that efficiency roll‐off can be effectively suppressed in such low concentrations. These findings pave a new way to exploit low cost and high efficiency PhOLEDs. 相似文献
88.
Jani Korhonen Timo Ojala Annu Ristola Manne Kesti Vesa Kilpelänaho Mikko Koskinen Eveliina Viippola 《Personal and Ubiquitous Computing》2007,11(7):577-589
This paper describes the Mobile Fair Diary (MFD), which is designed to allow a housing fair customer to make a personalized
digital recording of his/her visit to a hectic fairground for later use. The MFD is a hybrid interface service comprising
of an application for a camera equipped smart phone and a website accessed by a PC. The smart phone application is used for
taking context-aware notes such as visual codes, photos, dictations and text. The notes are uploaded onto a website, where
they can be viewed with a PC in a contextually ordered view for browsing, organizing and sharing. The MFD was empirically
evaluated in a real-life environment of use with genuine end users by a large-scale field trial at a national housing fair.
The results testify to the very successful design of the MFD with high usefulness. 相似文献
89.
Stanley P. Y. Fung Feifeng Zheng Wun-Tat Chan Francis Y. L. Chin Chung Keung Poon Prudence W. H. Wong 《Journal of Scheduling》2008,11(4):299-308
We study an on-line broadcast scheduling problem in which requests have deadlines, and the objective is to maximize the weighted
throughput, i.e., the weighted total length of the satisfied requests. For the case where all requested pages have the same
length, we present an online deterministic algorithm named BAR and prove that it is 4.56-competitive. This improves the previous
algorithm of (Kim, J.-H., Chwa, K.-Y. in Theor. Comput. Sci. 325(3):479–488, 2004) which is shown to be 5-competitive by (Chan, W.-T., et al. in Lecture Notes in Computer Science, vol. 3106, pp. 210–218,
2004). In the case that pages may have different lengths, we give a (
)-competitive algorithm where Δ is the ratio of maximum to minimum page lengths. This improves the (4Δ+3)-competitive algorithm
of (Chan, W.-T., et al. in Lecture Notes in Computer Science, vol. 3106, pp. 210–218, 2004). We also prove an almost matching lower bound of Ω(Δ/log Δ). Furthermore, for small values of Δ we give better lower bounds.
The work described in this paper was fully supported by grants from the Research Grants Council of the Hong Kong SAR, China
[CityU 1198/03E, HKU 7142/03E, HKU 5172/03E], an NSF Grant of China [No. 10371094], and a Nuffield Foundation Grant of UK
[NAL/01004/G]. 相似文献
90.
In this study, we propose a support vector machine (SVM)-based ensemble learning system for customer relationship management
(CRM) to help enterprise managers effectively manage customer risks from the risk aversion perspective. This system differs
from the classical CRM for retaining and targeting profitable customers; the main focus of the proposed SVM-based ensemble
learning system is to identify high-risk customers in CRM for avoiding possible loss. To build an effective SVM-based ensemble
learning system, the effects of ensemble members’ diversity, ensemble member selection and different ensemble strategies on
the performance of the proposed SVM-based ensemble learning system are each investigated in a practical CRM case. Through
experimental analysis, we find that the Bayesian-based SVM ensemble learning system with diverse components and choose from space selection strategy show the best performance over various testing samples. 相似文献