半沙漠地区中的生态住宅

项目地点:摩洛哥伊尔富德项目类型:建筑(住宅)开工日期:2006年元月该项目获2005年豪瑞可持续建筑大奖赛非洲中东地区提名奖     

A Novel Design of Compact Dual-Band Bandpass Filter for Wireless Communication Systems

Wireless Personal Communications - In this paper, design, fabrication, and measurement of a new microstrip dual-band bandpass filter with compact size and high selectivity characteristics for...     

The Role of β-Arrestins in Regulating Stem Cell Phenotypes in Normal and Tumorigenic Cells

β-Arrestins (ARRBs) are ubiquitously expressed scaffold proteins that mediate inactivation of G-protein-coupled receptor signaling, and in certain circumstances, G-protein independent pathways. Intriguingly, the two known ARRBs, β-arrestin1 (ARRB1) and β-Arrestin2 (ARRB2), seem to have opposing functions in regulating signaling cascades in several models in health and disease. Recent evidence suggests that ARRBs are implicated in regulating stem cell maintenance; however, their role, although crucial, is complex, and there is no universal model for ARRB-mediated regulation of stem cell characteristics. For the first time, this review compiles information on the function of ARRBs in stem cell biology and will discuss the role of ARRBs in regulating cell signaling pathways implicated in stem cell maintenance in normal and malignant stem cell populations. Although promising targets for cancer therapy, the ubiquitous nature of ARRBs and the plethora of functions in normal cell biology brings challenges for treatment selectivity. However, recent studies show promising evidence for specifically targeting ARRBs in myeloproliferative neoplasms.     

半沙漠地区中的生态住宅

项目地点:摩洛哥伊尔富德项目类型:建筑(住宅)开工日期:2006年元月该项目获2005年豪瑞可持续建筑大奖赛非洲中东地区提名奖     

One Cell,One Drop,One Click: Hybrid Microfluidics for Mammalian Single Cell Isolation

Generating a stable knockout cell line is a complex process that can take several months to complete. In this work, a microfluidic method that is capable of isolating single cells in droplets, selecting successful edited clones, and expansion of these isoclones is introduced. Using a hybrid microfluidics method, droplets in channels can be individually addressed using a co‐planar electrode system. In the hybrid microfluidics device, it is shown that single cells can be trapped and subsequently encapsulate them on demand into pL‐sized droplets. Furthermore, droplets containing single cells are either released, kept in the traps, or merged with other droplets by the application of an electric potential to the electrodes that is actuated through an in‐house user interface. This high precision control is used to successfully sort and recover single isoclones to establish monoclonal cell lines, which is demonstrated with a heterozygous NCI‐H1299 lung squamous cell population resulting from loss‐of‐function eGFP and RAF1 gene knockout transfections.     

Investigation of Adhesion Mechanism in Molten Silicon/Ceramics Systems

Silicon - An experimental study was conducted to investigate the interfaciale adhesion between molten silicon and TiB2, ZrB2 and HfB2 ceramics by using the sessile drop technique. Contact angle...     

The electrochemical behaviour of the carbon-coated Ni0.5TiOPO4 electrode material

Ni_0.5TiOPO₄ oxyphosphate exhibits good electrochemical properties as an anode material in lithium ion batteries but suffers from its low conductivity. We present here the electrochemical performances of the synthesized Ni_0.5TiOPO₄/carbon composite by using sucrose as the carbon source. X-ray diffraction study confirms that this phosphate crystallizes in the monoclinic system (S.G. P2₁/c). The use of the Ni_0.5TiOPO₄/C composite in lithium batteries shows enhanced electrochemical performances compared with the uncoated material. Capacities up to 200 mAh g⁻¹ could be reached during cycling of this electrode. Furthermore, an acceptable rate capability was obtained with very low capacity fading even at 0.5C rate. Nevertheless, a considerable irreversible capacity was evidenced during the first discharge. In situ synchrotron X-ray radiation was utilized to study the structural change during the first discharge in order to evidence the origin of this irreversible capacity. Lithium insertion during the first discharge induces an amorphization of the crystal structure of the parent material accompanied by an irreversible formation of a new phase.     

On the LiNi0.2Mn0.2Co0.6O2 positive electrode material

Layered LiNi_0.2Mn_0.2Co_0.6O₂ phase, belonging to a solid solution between LiNi_1/2Mn_1/2O₂ and LiCoO₂ most commercialized cathodes, was prepared via the combustion method at 900 °C for a short time (1 h). Structural, electrochemical and magnetic properties of this material were investigated. Rietveld analysis of the XRD pattern shows this compound as having the α-NaFeO₂ type structure (S.G. R-3m; a = 2.8399(2) ?; c = 14.165(1) ?) with almost none of the well-known Li/Ni cation disorder. SQUID measurements clearly indicate that the studied compound consists of Ni²⁺, Co³⁺ and Mn⁴⁺ ions in the crystal structure. X-ray analysis of the chemically delithiated Li_xNi_0.2Mn_0.2Co_0.6O₂ phases reveals that the rhombohedral symmetry was maintained during Li-extraction, confirmed by the monotonous variation of the potential-composition curve of the Li//Li_xNi_0.2Mn_0.2Co_0.6O₂ cell. LiNi_0.2Mn_0.2Co_0.6O₂ cathode has a discharge capacity of ∼160 mAh g⁻¹ in the voltage range 2.7-4.3 V corresponding to the extraction/insertion of 0.6 lithium ion with very low polarization. It exhibits a stable capacity on cycling and good rate capability in the rate range 0.2-2 C. The almost 2D structure of this cathode material, its good electrochemical performances and its relatively low cost comparing to LiCoO₂, make this material very promising for applications.