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81.
To determine the mechanism of measles virus-induced cell death, we studied the infection of Vero cells and monocytic cell lines with wild-type (Chicago-1) and vaccine (Edmonston) strains of measles virus. DNA fragmentation indicative of apoptosis was apparent by flow cytometry, agarose gel electrophoresis, and electron microscopy. Within syncytia, DNA strand breaks were demonstrated by end labeling with terminal transferase and then by visualization. 相似文献
82.
Dongwook Park Minnyeon Kim 《Quantum Electronics, IEEE Journal of》1996,32(8):1432-1440
This paper presents theoretical results on mode characteristics of surface-emitting (SE) lasers utilizing an active second-order grating section. Based on a coupled-mode approach, longitudinal modes and the associated space-harmonic transverse modes are calculated via a numerical technique. From these, the lasing-mode spectrum, near- and far-field patterns of the radiation mode, and the surface-emission power efficiency are obtained. Effects of the substrate reflector and the grating parameters are also investigated. Finally, comparisons are made with conventional, edge-emitting DFB lasers. The results indicate that with a suitable choice of structural parameter values, DFB SE lasers can be made to possess both the spectral discrimination of the conventional DFB lasers and the advantages of SE lasers at the same time and also that the second lowest longitudinal mode may be preferred over the fundamental longitudinal mode for many applications due to its symmetric field distribution 相似文献
83.
Jeong-Woo Choi Jun Hyo Park Shin Chul Lee Dong-Il Kim Won Hong Lee 《Korean Journal of Chemical Engineering》1995,12(5):528-534
The on-line sensing of viable cell weight in plant cell culture process is applied to analysis and control of process. The
fiber-optic fluorescence sensor was constructed to measure the NADH-dependent fluorescence inNicotiana tabacum plant cell culture and the analysis of fluorescence signal was done to be correlated with the viable cell weight. The structured
kinetic model for cell growth was proposed to estimate the theoretical viable cell weight. The dimensional analysis was proposed
for the interpretation of fluorescence signal, in which the path length, the inner filter effect and the hydrodynamic conditions
were considered as the key factors on fluorescence signal. The dimensional analysis and empirical correlation of fluorescence
signal to viable cell weight was applied to the interpretation of the detected fluorescence signal during cultivation. The
proposed interpretation of fluorescence signal using dimensional analysis was well correlated with the viable cell weight
estimated by the structured kinetic model as well as by empirical correlation. 相似文献
84.
Hyoung-Joon Park Hyoun-Ee Kim Doh-Yeon Kim 《Journal of the American Ceramic Society》1994,77(11):2828-2832
A quantitative method to evaluate the degree of whisker alignment in axisymmetric composite materials was developed. The angular distribution of the whiskers was analyzed by measuring the aspect ratios of the whiskers observed on a planar section. However, due to the large difference in the probability of whiskers being detected on the planar section (depending on whisker length and degree of alignment), the angular distribution of the whiskers observed on the planar section was significantly different from the actual distributions of the whiskers in three dimensions. Three-dimensional angular distributions were evaluated by comparing the aspect ratios observed on the planar section with those calculated under the assumption that the whisker angle fell in a Gaussian distribution with average angle of 90°. By this method, the degree of preferential alignment is expressed as the standard deviation of the Gaussian distribution. This quantification of whisker alignment is useful in analyzing the mechanical behaviors of composite materials reinforced with elongated particles. 相似文献
85.
K.-H. Zum Gahr R. Telle B. Zimmerlin S.-H. Park 《Materialwissenschaft und Werkstofftechnik》1992,23(9):329-338
Influence of grain size on mechanical properties and dry oscillating sliding wear of Al2O3-ceramics Specimens with average grain sizes varying between about 0.8 μm and 12 μm were produced by cold isostatic pressing of high purity Al2O3-powder followed by sintering between 1300°C and 1700°C. Hardness, Young's modulus, bending strength and fracture toughness were measured as a function of average grain sizes. Tribological tests were carried out on the different microstructures at normal laboratory air and room temperature by using a ring-on-block tribometer. Experimental results showed the dependence of mechanical properties on grain size, hardness and bending strength obeying a Hall-Petch type relation, approximately. Coefficient of friction was relatively independent of grain size under the test conditions used. However, wear intensity increased substantially if a critical grain size was surpassed. This was due to a change in mechanisms of material removal which was confirmed by scanning electron microscopical studies of the worn surfaces. 相似文献
86.
87.
Park Y.C. Lee K.Y. Youn D.H. Kim N.H. Kim W.K. Park S.H. 《IEEE transactions on bio-medical engineering》1992,39(8):868-871
An efficient algorithm detecting the presence of a fetal QRS complex is presented. The proposed fetal QRS detection method computes the averaged magnitude of the difference between the fetal ECG signal and the reference signal to detect the fetal QRS event. The detected fetal QRS complexes are exponentially averaged to generate the template signal which can track the slowly varying shape of the fetal ECG signal. As an effort to obtain improved detection performances, two approaches of normalizing the fetal ECG signal and the template are considered. 相似文献
88.
Disagreement exists in the literature concerting the activity of NiO in (Ni,Mg)O solid solutions. Ideal behavior, as well as strong positive deviations and strong negative deviations from ideality, has been reported. In the present study, the activity of NiO was determined by electromotive force measurements using the solid-state cell Pt/Ni-NiO/0.92ZrO2 -0.08Y2 O3 /Ni-(Ni,Mg)O/Pt. The compositions studied had NiO mole fractions of 0.1,0.3,0.5,0.7, and 0.9. In agreement with theoretical expectations, the solid solutions exhibited ideal behavior at 882° and 982°C. Possible reasons for the conflicting results in the literature arc presented. 相似文献
89.
Experimental studies on the aerodynamic coupling effect on natural frequencies and flutter instability of rotating disks
are investigated in this paper. The experiments performed using a vacuum chamber and optical disks give two main results.
One is that the aerodynamic effect by surrounding air reduces the natural frequencies and critical speeds of the vibration
modes in pre-flutter regions. The other is that the natural frequency of the disk rotating at ambient atmospheric pressure
is equal to that in vacuum at the flutter onset speed where the disk experiences aero-induced flutter. In post-flutter regions,
the aerodynamic coupling between the disk and surrounding air increases the natural frequencies of the disk.
Received: 17 June 2002/Accepted: 7 October 2002
The work was supported by Grant No. R11-1997-042-090001-0 of the Center for Information Storage Devices designated by the
Korea Science & Engineering Foundation.
Paper presented at the 13th Annual Symposium on Information Storage and Processing Systems, Santa Clara, CA, USA, 17–18 June,
2002 相似文献
90.
The Error-in-Variables Model (EVM) applies to a large class of problems in parameter estimation in which there is error in all the variables. This property makes it of more general applicability than the widely used technique of ordinary Least Squares. While there is a voluminous literature on EVM there is nothing on a general method for designing experiments when EVM applies. In this paper we present an extension of the concept of D-optimality to provide such a general method. It is illustrated by applying it to the estimation of copolymer reactivity ratios and to fitting an ellipse. 相似文献