A test for the statistical significance of DNA sequence similarities for application in databank searches

A method is developed, based on word-searching, which provides a rapid test for the statistical significance of DNA sequence similarities for use in databank searching. The method makes allowance for the lengths and dinucleotide compositions of the sequences being compared. A way is also described to calculate the power of the test, i.e. the probability of detecting a given similarity as being statistically significant. The effects on the power of the test of the scoring method, word length, sequence length, and sequence composition are examined. A novel scoring method is shown to be superior to the method currently used in most word-searching algorithms.     

Erosion und Korrosion of metallischer Werkstoffe in feststoffhaltigen Wässern

Erosion and corrosion of metallic materials in particle containing aqueous solutions The combined effect and mutual influence, respectively, of erosion and corrosion of metallic materials in particle containing flows was investigated. Materials under investigation are carbon steel of different hardness levels, ferritic chromium steel, austenitic stainless steel and brass. Corrosive medium was deionized water, acid (pH 4.5), alkaline (pH 10) and chloride (3% NaCl) solution. Quartz particles were used as abrasive at various particle concentrations, grain sizes and flow velocities. For comparison, tests were performed with pure water and under conditions of idle corrosion. Mechanical or corrosive influences dominate depending on material and test conditions, in some cases, synergistic effects of both mechanisms cause an increased mass loss.     

Failure loads for notched graphite/epoxy laminates with a softening strip

The strengths of two graphite/epoxy notched laminate systems with a softening strip were investigated. The softening strip was created by replacing the 0°-graphite/epoxy plies by a glass/epoxy composite. Experimental results indicated that the use of softening strips could significantly increase the laminate strength. Analysis was performed with finite elements developed using the classical laminated plate theory and was shown to be adequate. A simple point-stress failure criterion was used to predict the strength of notched laminates with softening strips and the result was found to be satisfactory.     

A construction of codes with exponential error bounds on arbitrarydiscrete memoryless channels

This correspondence proposes an explicit construction of codes achieving capacity for arbitrary discrete memoryless channels. The proposed code is obtained by concatenating variable inner codes and an algebraic geometry code. Further, we clarify that the proposed code achieves the error exponent obtained by Forney for concatenated codes     

Assessing Environmental Risks: Lessons From Superfund

This essay analyzes the use of risk assessment in Superfund, the controversial American hazardous waste cleanup programme. We argue that risk assessment has been used in three ways in discussing policy options in this programme: as a metric for assessing performance; as a means for resolving conflicts; and as a tool for comparing different environmental initiatives. Use of risk reduction as an analytical tool in European efforts to clean up hazardous waste sites is discussed. We conclude that while risk assessment has potential utility for each of these applications, there are also accompanying technical and political difficulties.     

Enhanced electron emission from phosphorus-doped diamond-cladsilicon field emitter arrays

Undoped and phosphorus (P)-doped diamond-clad Si field emitter arrays have been successfully fabricated using microwave plasma chemical vapor deposition (MPCVD) technology. The electron emission from the blunt diamond-clad microtips are much higher than those for the pure Si tips with sharp curvature due to a lower work function. Furthermore, the characteristics of emission current against applied voltage for the P-doped diamond-clad tips show superior emission at lower field to the undoped ones. After the examination of Auger electron spectroscopy (AES) and electrical characteristics of as-grown diamond, such a significant enhancement of the electron emission from the P-doped diamond-clad tips is attributed to a higher electron conductivity and defect densities