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81.
F Namouni F Doz ML Tanguy E Quintana J Michon H Pacquement E Bouffet JC Gentet D Plantaz P Lutz JP Vannier P Validire S Neuenschwander L Desjardins JM Zucker 《Canadian Metallurgical Quarterly》1997,33(14):2368-2375
This study investigates the role of high-dose chemotherapy with haematopoietic stem cell rescue as consolidation treatment in high-risk retinoblastoma (extraocular disease at diagnosis or relapse or invasion of cut end of optic nerve). 25 patients received high-dose chemotherapy including carboplatin (250 mg/m2/day from day 1 to day 5 for the 6 first patients and 350 mg/m2/day from day 1 to day 5 for the other patients), etoposide (350 mg/m2/day from day 1 to day 5) and cyclophosphamide (1.6 g/m2/day from day 2 to day 5) (CARBOPEC) followed by autologous haematopoietic stem cell rescue. 19 patients received this drug combination for chemosensitive extraocular relapse. The other 6 patients with histological high-risk factors were given this treatment as consolidation after enucleation and conventional chemotherapy. The three year disease-free survival was 67.1%. In 7 of the 9 relapsing patients, the first site of relapse was the central nervous system. All patients with central nervous system disease died except one. The main toxicity was haematological and digestive (mucositis and diarrhoea). 2 of the 13 evaluable patients had grade III and IV ototoxicity. One patient experienced an acute grade I reversible cardiotoxicity. The CARBOPEC regimen seems to be a promising therapeutic strategy in patients with high-risk retinoblastoma, especially those with bone and/or bone marrow involvement. This treatment did not improve the outcome of patients with central nervous system disease. 相似文献
82.
The physical properties of aluminum thin films depend strongly on their microstructure, which can be characterized using different techniques. In the present work, aluminum thin films—grown with different thickness on silicon substrates—were analyzed by atomic force microscopy (AFM) and grazing incidence x-ray techniques. The AFM was used as a high-resolution profilemeter for measuring edge angles, step heights, surface microstructure, and roughness. The structural properties (such as crystallographic orientation, crystallite size, and phase identification) were analyzed by grazing incidence x-ray diffraction. For small thickness, AFM images show small nucleation sites because of the short time of growth. Grain size grows as the thickness increases, and film morphology seems to be uniform with large grains. The AFM results of as-grown films show a linear increase in roughness along with thickness. Roughness values decrease with aging time after film preparation, until a constant value is observed. All films mainly have (111) orientation, and its intensity grows with film thickness, with respect to the (200) and (220) peaks. As the film thickness increases, the surface stress decreases. 相似文献
83.
Ionomeric composites based on sepiolite and hydrogenated poly(styrene butadiene) block copolymer were obtained and characterized from a microstructural and electrical point of view. Before blending, because of the high silanol group concentration in the sepiolite, the latter could be organophilized with suitable coupling agents. The resulting materials were easily processed into thin films or membranes 0.2–0.4 mm thick, their conductivity in some cases approaching 10?1 S/cm. Their suitability for film formation and good electrical properties indicate potential applications as electrolytes in polymer fuel cells. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 86: 3512–3519, 2002 相似文献
84.
P Casolo D Mosca C Amorotti B Drei A Raspadori P Di Blasio E Ganz G De Luca G Colli R De Maria D Amuso 《Canadian Metallurgical Quarterly》1997,68(2):207-11; discussion 212
Primary and sole breast lymphoma is a very rare disease. With the review of our series of 616 cases operated on for breast cancer, only 3 cases (0.48%) of primary breast non-Hodgkin lymphoma (LNH) have been observed. The authors outline the problems concerning diagnosis and therapy of this rare disease: pathological and immunohistochemical aspects are discussed. They stress the importance of staging in order to plan a correct multidisciplinary approach. 相似文献
85.
86.
Harrist R. Steven; Quintana Stephen M.; Strupp Hans H.; Henry William P. 《Canadian Metallurgical Quarterly》1994,31(1):49
[Correction Notice: An erratum for this article was reported in Vol 31(3) of Psychotherapy: Theory, Research, Practice, Training (see record 2009-17141-002). This article contained, as Figure 1, an SASB model. The authorship and copyrights for the model were not acknowledged. The following acknowledgement should have been included: "Adapted from Benjamin (1984). Principles of Prediction using Structural Analysis of Social Behavior (SASB). In R. A. Zucker, J. Aronoff, and A. J. Rabin (Eds.), Personality and the Prediction of Behavior (pp. 121- 174). New York: Academic." An apology is offered to the author, Dr. Lorna Smith Benjamin. The particular version used in the article was developed in collaboration with Clinton W. McLemore.] Investigated the internalization of positive aspects of therapist–patient (TP) interactions among 70 patients and their 16 therapists who participated in a 5-yr study (H. H. Strupp et al, unpublished) of time-limited dynamic psychotherapy. Patients sought help for anxiety, depression, or other problems with a clear interpersonal component and qualified for an Axis I or Axis II diagnosis on the Diagnostic and Statistical Manual of Mental Disorders-III (DSM-III). Instruments included the Structural Analysis of Social Behavior and outcome measures of depression, anxiety, and psychological functioning. Patients' intrapsychic functioning became more similar to interpersonal activity in the TP relationship over the course of psychotherapy. Intrapsychic movement toward interpersonal activity in the TP relationship was associated with positive outcome on measures of depression, anxiety, and on independent clinician ratings of patient psychological functioning. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
87.
Juntunen Cindy L.; Atkinson Donald R.; Reyes Carla; Gutierrez Maria 《Canadian Metallurgical Quarterly》1994,31(2):327
Investigated whether (1) feminist identity development for women therapists was related to their use of feminist therapy behaviors (FTBs) and (2) feminist identity development and use of FTBs for women therapists were related to self-identification as a feminist therapist. 153 women psychologists (aged 30–77 yrs) were administered a women's issues in therapy questionnaire, which included a short version of the Feminist Identity Scale (FIS; K. M. Rickard, 1989, 1990). Ss were categorized into stages of feminine identity development according to their scores on 4 subscales of the FIS: Passive-Acceptance (PA), Revelation (REV), Embeddedness (EMB), and Synthesis (SYN). Ss scoring high on SYN and REV, and low on PA, reported greater use of FTBs; scores on the EMB were not related to the use of FTBs. All 4 subscales were predictive of women therapists who self-identified as feminist therapists. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
88.
Sandra Aparecida de Assis Pedro Fernandes Bruno Sommer Ferreira Joaquim MS Cabral Olga Maria Mascarenhas Faria Oliveira 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》2004,79(3):277-280
A partially purified extract of pectinmethylesterase (PME) from acerola fruit was immobilized on various supports: glass, celite, chrysotile, agarose, concanavalin A Sepharose 4B, egg shell, polyacrylamide and gelatin. In addition, reticulation with glutaraldehyde was assessed, as well as the use of gelatin in the presence of celite, glass and silica. The highest immobilization yields were obtained when the pectinmethylesterase was immobilized in concanavalin A Sepharose 4B (81.7%) and in gelatin‐water (78.0%). Copyright © 2004 Society of Chemical Industry 相似文献
89.
Molecular model systems based on propyl phosphonic acid (ppa) were studied by means of density functional theory calculations in order to describe the acid-acid interaction and the formation of the hydration sphere. The formation of ppa dimers is reported and the energetic difference between two dimer structures is presented. The hydration sphere of ppa was represented by model systems ppa(H2O)n, for which the system with n=4 formed the first hydration sphere (h1), while n=7 can be considered a good approximation to the complete inner hydration sphere around the phosphonic acid group. The study of the ppa-H+ (H2O)n model systems showed an interesting structural behavior comparatively to the ppa(H2O)n systems. The protonated acids exhibited equivalent phosphorous-oxygen bonds and a general molecular structure is proposed to represent these protonated species. 相似文献
90.
Daniela D'Amato Maria Rosaria Corbo Matteo Alessandro Del Nobile & Milena Sinigaglia 《International Journal of Food Science & Technology》2006,41(10):1152-1157
In enology, alcoholic fermentation is a complex process involving several mechanisms. Slow and incomplete alcoholic fermentation is a chronic problem for the wine industry and factors leading to sluggish and stuck fermentations have been extensively studied and reviewed. The most studied cause of sluggish and stuck fermentation is the nitrogen content limitation. Nevertheless, other factors, such as temperature of fermentation and sugar concentration can affect the growth of yeasts. In this study we modelled the yeast growth‐cycle in wine model system as a function of temperature, sugar and ammonium concentrations; the individual effects and the interaction of these factors were analysed by means of a quadratic response surface methodology. Cell concentrations and weight loss were monitored in the whole wine fermentation process. The results of central composite design show that lower is the availability of nitrogen, higher is the cell growth rate; moreover, initial nitrogen concentration also influences survival time of Saccharomyces cerevisiae. 相似文献