Driver Deadtime Control and Its Impact on System Stability of Synchronous Buck Voltage Regulator

Driver dead-time control is a popular scheme used to prevent the occurrence of the shoot-through issue in a synchronous Buck voltage regulator. As the switching frequency is continually increasing in today's converter design, the deadtime interval is now long enough relative to the switching period to impact the system performance. In addition to its impact on efficiency, driver dead-time also impacts loop gain and system stability, especially under the critical load condition. In this paper, the influence of driver dead time on the synchronous buck converter is investigated in detail. With voltage mode control, the system loop gain will change under different load conditions due to the deadtime impact. The deadtime may cause sub-harmonic current ripple in the voltage regulator with sample-and-hold current mode control, while its impact on the peak current mode control can be ignored. Design equations are provided to avoid this issue. Some analysis data are included and compared to experimental results.     

JWL++: A Simple Reactive Flow Code Package for Detonation

JWL++ is a simple Reactive Flow model that includes time‐dependent reaction in prompt detonation. It consists of a Murnahan unreacted equation of state, a JWL reacted EOS, a mixer for the two EOS's and a single‐time‐constant exponential rate. The mixing can be done by four ways, using either pressure or pressure plus artificial viscosity in the rate, and also using either an analytic function or a pressure equilibrator. The model reproduces the Size Effect and detonation front curvature. Detonation failure can also be induced. JWL++ propagates also through an arbitrary geometry in 3‐D without the need for pre‐run program burn calculations. It is slower than a JWL/program “Burn” but faster than “Ignition & Growth”.     

Tracking severe weather storms in Doppler radar images

We describe an automatic storm-tracking system to help with the forecasting of severe storms. In this article, we present the concepts of fuzzy point, fuzzy vector, fuzzy length of a fuzzy vector, and fuzzy angle between two nonzero fuzzy vectors, that are used in our tracking algorithm. These concepts are used to overcome some of the limitations of our previous work, where fixed center-of-mass storm centers did not provide smooth tracks over time, while at the same time, their detection was very threshold sensitive. Our algorithm uses region splitting with dynamic thresholding to determine storm masses in Doppler radar intensity images. We represent the center of a hypothesized storm using a fuzzy point. These fuzzy storm centers are then tracked over time using an incremental relaxation algorithm. We have developed a visualization program using the X11 Athena toolkit for our storm visualization tool. The algorithm was tested on seven real radar image sequences obtained from the Atmospheric Environment Service radar station at King City, Ontario, Canada. We can obtain storm tracks that are long and smooth and which closely match an expert meteorologist's perception. © 1998 John Wiley & Sons, Inc. Int J Imaging Syst Technol, 9, 201–213, 1998     

The ovine pars tuberalis secretes a factor(s) that regulates gene expression in both lactotropic and nonlactotropic pituitary cells

The purpose of this study was to determine whether the cells of the ovine pars tuberalis (PT) secrete a factor(s) that can influence the activity of cells in the pars distalis (PD). By Northern blotting of total RNA isolated from PD cells that had been stimulated in the presence of cycloheximide (10 micrograms/ml), PT cell-conditioned medium was shown to induce a significant increase in the expression of the early response gene, c-fos, above both PD cell-conditioned and nonconditioned medium control levels (P < 0.05). Although forskolin (5 microM) induced a weak increase in c-fos expression in PD cells, the effect of PT medium conditioned in the presence of forskolin enhanced this expression more than additively (P < 0.05); furthermore, this effect was reversed by melatonin. These results are consistent with the release of a factor(s) from the PT, which for simplicity we have called tuberalin. This factor was released from PT cells in a time-dependent and cycloheximide-sensitive manner and was resistant to heating at 100 C for 10 min. Tuberalin activity could be size-fractionated using molecular size cut-off filters to produce activity in both the 1- to 10-kDa and more than 10-kDa size ranges. The activities in both of these fractions were sensitive to trypsin degradation and, therefore, appeared to be peptidergic. However, it was not clarified whether the biological activities were due to one or two components. Tuberalin also induced c-fos expression in other cell types, including GH3 and NIH3T3 cells. Dual labelling of PD cells by in situ hybridization using riboprobes for c-fos and PRL demonstrated that both the less than and more than 10-kDa fractions of tuberalin activated c-fos expression in some, but not all, lactotrophs in PD cell cultures, suggesting that a primary function of the PT is to regulate the activity of lactotrophs. This was supported further by enhanced secretion of PRL from PD cells in the presence of either PT-conditioned medium or PT cells in coculture. In addition, PT-conditioned medium was found to increase c-fos in a second cell type, which did not hybridize positively for PRL, indicating the existence of other endocrine interactions between the PT and PD.     

Coexpression of leptin receptor and preproneuropeptide Y mRNA in arcuate nucleus of mouse hypothalamus

Leptin, the protein product of the adipose tissue-specific ob (obese) gene (1), reduces the body weight, adiposity and food intake of obese ob/ob mice on peripheral or central injection (2, 3, 4). [125I]leptin binding has been detected in mouse choroid plexus (5), from which a leptin receptor gene was expression cloned (5). The gene has at least 6 splice variants (6, 7). Leptin receptor mRNA was localized in the hypothalamus by in situ hybridization being particularly abundantly expressed in the arcuate nucleus (8). There is evidence linking the physiological effects of injected leptin with hypothalamic neuropeptide Y (9, 10) (NPY), which has potent central effects on food intake and energy balance (11), and is also expressed in the arcuate nucleus. Here we report dual in situ hybridization studies for leptin receptor and NPY gene expression in the mouse arcuate nucleus, where the majority of cells examined expressed both genes. This provides the first direct evidence that leptin acts on cells that express NPY mRNA.     

Effects of counselor statements on rater judgments of client self-exploration.

Examined the influence of counselor statements on rater judgements of client self-exploration. Audiotaped segments of counseling interviews that included both counselor and client statements and identical autiotaped segments, but with the counselors' statements deleted, were rated on client self-exploration by separate groups of raters (totaling 20 counseling graduate students). A significantly positive correlation was found between the 2 sets of ratings. With 1 exception, no significant differences were found for each segment. Finally, no differences were found between ratings for segments, unedited and edited, in which counselors were functioning at high levels of accurate empathy and ratings in which counselors were functioning at low levels of accurate empathy. (34 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Gender affects rats' central nervous system histaminergic responses to dietary manipulation

The histaminergic system (histamine and its H1-receptor) of the central nervous system has been implicated in control of food intake. The reported studies were designed to examine the effects of food restriction and very low (1%) protein diets on central nervous system H1-receptors in male and female rats. In a series of experiments, groups of rats were freely fed a 25% protein diet, a 1% protein diet, or fed the 25% protein diet at 4 g/100 g body weight for 14-20 d. When freely fed 25% protein diets, females had higher whole-brain H1-receptor binding than males on d 1 (female 122.36 +/- 4.53 and male 65.78 +/- 3.82 pmol/g protein; P < 0.001). Changing diets affected central H1-receptor binding in both males and females (P < 0.003). When rats were fed both restricted levels of food and 1% protein diets, the receptor binding of males increased by d 5 whereas that of females decreased by d 5 (P < 0.001). When fed 1% protein diets, females had decreased H1-receptor binding (98.4 +/- 2.38 pmol/g protein) and that in males increased to 119.81 +/- 5.09 pmol/g protein. After 15 d, females had eaten significantly more food than males: females 166 +/- 4.9 g, males 124 +/- 1.9 g (P< 0.0007). Males had a significantly greater weight loss than females: males -28.8 +/- 2.6 g, females -17.08 +/- 0.97 g (P < 0.0007). When fed restricted diets, females had decreased H1-receptor binding (93.81 +/- 5.58 pmol/g) whereas binding in males increased to 111.27 +/- 8.55 pmol/g. Preliminary saturation binding studies indicated that restricted food intake lowered receptor density (females consuming 25% protein: 715 +/- 30 pmol/g protein; female restricted: 467 +/- 28 pmol/g protein, P < 0.05), while 1% protein increased receptor sensitivity, i.e., lowered KD (males consuming 25% protein: 15.3 +/- 1.8 nmol; males fed low protein: 2.8 +/- 0.27 nmol). This study suggests that dietary manipulation affects central H1-receptor binding in a gender-specific manner, thereby modulating central histaminergic activity during food or protein deficit.     

The concept of psychological regression: Metaphors, mapping, Queen Square, and Tavistock Square.

The term “regression” refers to events in which an individual changes from his or her present level of maturity and regains mental and behavioral characteristics shown at an earlier point in development. This definition has remained constant for over a century, but the implications of the concept have changed systematically from a perspective in which regression was considered pathological, to a current view in which regression may be seen as a positive step in psychotherapy or as a part of normal development. The concept of regression, famously employed by Sigmund Freud and others in his circle, derived from ideas suggested by Herbert Spencer and by John Hughlings Jackson. By the 1940s and '50s, the regression concept was applied by Winnicott and others in treatment of disturbed children and in adult psychotherapy. In addition, behavioral regression came to be seen as a part of a normal developmental trajectory, with a focus on expectable variability. The present article examines historical changes in the regression concept in terms of mapping to biomedical or other metaphors, in terms of a movement from earlier nativism toward an increased environmentalism in psychology, and with respect to other historical factors such as wartime events. The role of dominant metaphors in shifting perspectives on regression is described. (PsycINFO Database Record (c) 2011 APA, all rights reserved)