Production of periodic bars by vibrational drawing

One aspect of improving blade production is the production of blanks with a periodic profile from nickel and titanium alloys. In certain cases of vibrational deformation (in particular, in vibrational drawing), periodic change in the diameter of rod or wire over its axis is observed. This is associated with frictional oscillation and stability loss in deformation (on reaching the yield point in the rod, with the appearance of necking, or as a result of inertial forces). Formulas are obtained for use in determining the conditions of unstable deformation and stabilizing the production of periodic bars by regulating the parameters of vibrational drawing.     

Publication, specialization, and fragmentation: Psychology in the academy.

Argues that W. Thorngate's (see record 1991-03036-001) proposals to alter the academic reward system to reduce production of psychological literature are based on a rationalist-constructivist conception of the social orders of science and academia. A radical rethinking of psychologists' views on the science of psychology will be necessary for avoiding fragmentation of the discipline. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Gender differences in the relationship between left ventricular size and ambulatory blood pressure in borderline hypertension. The HARVEST Study

AIM: To assess whether the are gender differences in cardiac adaptation to raised blood pressure levels in young subjects with borderline to mild hypertension. METHODS AND RESULTS: In 499 18-45-year-old stage I hypertensive subjects (377 men and 122 women) with a mean age of 33 +/- 9 years and office blood pressure of 146 +/- 11/ 94 +/- 6 mmHg, ambulatory blood pressure monitoring in duplicate, echocardiography and 24-h urinary catecholamines measurement were performed. RESULTS: The whole group was divided into quartiles of increasing daytime blood pressure and differences in left ventricular echocardiographic data were analysed in the two sexes separately. In men no left ventricular parameter differed across the quartiles, while in women left ventricular mass, posterior wall thickness and interventricular septum thickness showed a clear tendency to increase with increasing levels of systolic blood pressure. In multiple regression analysis, daytime systolic blood pressure explained only a small fraction of the variance in left ventricular parameters in men, while in women daytime systolic blood pressure was a main determinant of left ventricular mass and posterior wall and septal thicknesses. Body weight explained most of the variance in all dimensional parameters in men. In women weight was an important predictor of left ventricular mass and diameter, but was unrelated to left ventricular posterior wall and septal thicknesses. CONCLUSIONS: Daytime systolic blood pressure is the most important predictor of left ventricular mass and geometry in pre-menopausal women with stage I hypertension, while in men left ventricular dimensional indices are chiefly explained by body weight.     

Twin-tubes: 3D tracking based on the ATLAS muon drift tubes

The Monitored Drift Tubes (MDTs) of the ATLAS Muon Spectrometer have been paired to form so-called twin-tubes to measure the coordinate which runs along the wire direction. This modification endows the MDTs with full 3D track reconstruction using specially designed electronic boards. The performance of the twin-tubes has been measured for an equipped MDT chamber at the ATLAS Muon Cosmic Ray Test Stand at NIKHEF. The efficiency of a twin-tube has been determined to be 99.8%, and the measured resolution 17 cm per hit. By equipping one multilayer consisting of three layers and combining the measurements a resolution of 10 cm has been obtained.     

Optical neuron by use of a laser diode with injection seeding andexternal optical feedback

We present an all-optical neuron by use of a multimode laser diode that is subjected to external optical feedback and light injection. The shape of the threshold function, that is needed for neural operation, is controlled by adjusting the external feedback level for two longitudinal cavity modes of the laser diode individually. One of the two modes corresponds to the output of the neuron, light injection at the wavelength of this mode provides excitatory input. Light injection in the other mode provides inhibitory input. When light corresponding to two input signals is injected in the same mode, summation of input signals can be achieved. A rate-equation model is used to explain the operating principle theoretically. The proposed injection seeding neuron is built using free-space optics to demonstrate the concept experimentally. The results are in good agreement with the predictions from the rate-equation model. Some experimental results show threshold functions that are preferable from a neural-network point of view. These results agree well with injection locking theory and experiments reported in literature.     

Effect of evening versus morning benazepril on 24-hour blood pressure: a comparative study with continuous intraarterial monitoring

In a single-blind, in-patient, crossover study, the influence on the circadian blood pressure (BP) profile of the 9:00 a.m. versus the 9:00 p.m. acute administration of a single dose of benazepril 10 mg, a new angiotensin-converting-enzyme inhibitor, was assessed in 10 hypertensive patients by means of 24-hour intraarterial ambulatory BP monitoring. Mean 24-hour BP for the three treatments (placebo, benazepril a.m., benazepril p.m.) were 155/93, 131/83 and 138/86 mmHg, respectively. No significant differences between the two benazepril schedules were found in terms of either 24-hour or day-time and night-time mean BP values. However, hourly averages showed that benazepril a.m. had a more sustained antihypertensive effect than benazepril p.m., where a loss of efficacy was observed 19 hours after the administration. BP responses to static and dynamic exercise and to cold pressor test were unchanged after both benazepril schedules, as were BP peaks. These results demonstrate that acute benazepril administration markedly reduces systolic and diastolic BP. The morning administration is preferable because it more effectively covers the whole 24 hours than an evening dose.     

Engineering the stability and the activity of a glycoside hydrolase

Glycosidases, the enzymes responsible in nature for the catabolism of carbohydrates, are well-studied catalysts widely used in industrial biotransformations and oligosaccharide synthesis, which are also attractive targets for drug development. Glycosidases from hyperthermophilic organisms (thriving at temperatures > 85 °C) are also interesting models to understand the molecular basis of protein stability and to produce robust tools for industrial applications. Here, we review the results obtained in the last two decades by our group on a β-glycosidase from the hyperthermophilic Archaeon Sulfolobus solfataricus. Our findings will be presented in the general context of the stability of proteins from hyperthermophiles and of the chemo-enzymatic synthesis of oligosaccharides.     

Review of Methods of theoretical psychology.

Reviews the book, Methods of theoretical psychology by André Kukla (see record 2001-18914-000). This comprehensive survey of the tools of theoretical psychology is the culmination of the author's previous writings (e.g., Kukla 1989, 1995) wherein he tried to "convince psychologists that our discipline had suffered from a gross and systematic underestimation of the scope, variety, and import of theoretical work" and "persuade my colleagues that there are many important theoretical issues the resolution of which does not call for empirical research" (p. xi). This is not a book in theoretical psychology (the author cites as examples the volumes by Marx and Hillix, and Wolman), but a book about theoretical psychology, the "types of theoretical activities" that "require nothing but thinking" (p. xi). Notable is the book's epigraph, a quotation from Jerry Fodor claiming that the distinction between psychological and philosophical theorizing is merely heuristic, and issuing the moral challenge for a plurality of argument styles that transcends disciplines. For Kukla has written a book about the logic of science, or what was traditionally referred to as the philosophy of science, and, as might be expected, examples are strewn throughout from the natural sciences as well as some classic theoretical problems in psychology, most notably, cognitive science. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Review of Images, Perception and Knowledge.

Reviews the book, Images, Perception and Knowledge edited by J. M. Nicholas. There are parts of this book that are worth reading, but the total is fragmentary. The reviewers get some artificial intelligence and computer simulation (Baylor & Racine), some brain function (Hebb, Pribram), some experimental psychology (Bugelski, Rosenberg, Paivio), some conceptual (Natsoulas, Henle, Pylyshyn) and philosophical (Hamlyn, Alston, Sloman) analysis, and out comes a bound entity entitled 'Images, Perception, and Knowledge.' It is true that all three of these topics are discussed at length, but they do not seem to constitute a well defined theme. The only justification for calling this a book is that all the parts are concerned with cognition. The reviewers see this 'conference book' as neither a conference (half of the book is reprinted) nor a book (it is more like a journal). The reviewers recommendation therefore, is that you not buy it, but that you borrow it so that you can take advantage of the individual chapters which are, in general, quite good. The epitaph for this effort could well be that 'the sum of the parts is greater than the whole.' (PsycINFO Database Record (c) 2010 APA, all rights reserved)