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141.
Aerial vehicle networks (AVNs) compose a large number of heterogeneous aerial nodes, such as unmanned aerial vehicles, aircrafts and helicopters. The main characteristics of these networks are the high mobility of aerial nodes and the dynamic network topology. AVNs represent attractive targets for attackers due to the fact that aerial nodes could be connected to an untrusted network and hence lead the attackers to launch lethal threats, e.g., aircraft crash. Therefore, the security of AVNs is mandatory. In this article, we examine the challenges of cyber detection methods to secure AVNs and review exiting security schemes proposed in the current literature. Furthermore, we propose a security framework to protect an aircraft (SFA) against malicious behaviors that target aircrafts communication systems. Numerical results show that SFA achieves a high accuracy detection and prediction rates as compared to the current intrusion detection for aircrafts communication system. 相似文献
142.
143.
Bichlmaier I Kurkela M Joshi T Siiskonen A Rüffer T Lang H Finel M Yli-Kauhaluoma J 《ChemMedChem》2007,2(6):881-889
The tricyclic sesquiterpenol (+)-longifolol served as a lead structure for the design of inhibitors of the human UDP-glucuronosyltransferase (UGT) 2B7. Twenty-four homochiral and epimeric longifolol derivatives were synthesized and screened for their ability to inhibit the enzyme. The absolute configuration at the stereogenic center C1' was determined by X-ray crystallography and 2D NMR spectroscopy (gHSQC, gNOESY). The phenyl-substituted secondary alcohol 16 b (beta-phenyllongifolol) displayed the highest affinity toward UGT2B7, and its inhibitory dissociation constant was 0.91 nM. The mode of inhibition was rapidly reversible and competitive. The inhibitor was not glucuronidated by UGT2B7 or other hepatic UGTs, presumably as a result of the high steric demand exerted by the phenyl group. Inhibition assays employing 14 other UGT isoforms suggested that inhibitor 16 b was highly selective for UGT2B7. 相似文献
144.
A set of 76 derivatives of the epimeric tricyclic sesquiterpenols longifolol and isolongifolol was subjected to inhibition and glucuronidation assays employing the human UDP-glucuronosyltransferase (UGT) 2B7. Detailed structure-activity relationships (SARs) with respect to functionality, stereochemical properties, and steric features were derived. To gain further insight into the SARs of UGT2B7 ligands herein, we have developed a 3D-quantitative structure-activity relationship (3D-QSAR) using Comparative Molecular Similarity Analysis (CoMSIA). The formation of the enzyme-inhibitor complex was predominantly controlled by spatially directed hydrophobic interactions. The glucuronidation rate was significantly influenced by the steric demand of substituents in proximity of the nucleophilic hydroxy group. The glucuronidation of the compounds was prevented by the introduction of bulky substituents such as isopropyl, tert-butyl, and phenyl groups. The epimeric longifolol derivatives of series D were the best inhibitors displaying IC(50) values as low as 4.6 nM. This study shows that high-potency substrates can be turned into potent inhibitors by addressing functional, stereochemical, and steric properties. 相似文献
145.
An experimental procedure that evaluates the quality of a grasp is developed. In this procedure human subjects grasp a rigid object that is subjected to an external load. Three formulations that capture the sense of grasping quality through the energy level stored in the gripper, maximum value of the applied finger forces, and through the distribution of the grasping forces are considered. The applied finger forces are measured and the quality values of the grasp based on these three different formulations are computed. These grasping quality values are compared with numerical human assessments, that are obtained via a psychophysical magnitude estimation method. We derive an augmented weighted functional that combines these three formulations, and show that it exhibits a high correlation with human quality assessment. Our results demonstrate that the most dominant mechanism that characterizes the quality of a rigid body grasp is the uniformity level of the contact forces. © 1997 John Wiley & Sons, Inc. 相似文献
146.
General theory of remote gaze estimation using the pupil center and corneal reflections 总被引:2,自引:0,他引:2
This paper presents a general theory for the remote estimation of the point-of-gaze (POG) from the coordinates of the centers of the pupil and corneal reflections. Corneal reflections are produced by light sources that illuminate the eye and the centers of the pupil and corneal reflections are estimated in video images from one or more cameras. The general theory covers the full range of possible system configurations. Using one camera and one light source, the POG can be estimated only if the head is completely stationary. Using one camera and multiple light sources, the POG can be estimated with free head movements, following the completion of a multiple-point calibration procedure. When multiple cameras and multiple light sources are used, the POG can be estimated following a simple one-point calibration procedure. Experimental and simulation results suggest that the main sources of gaze estimation errors are the discrepancy between the shape of real corneas and the spherical corneal shape assumed in the general theory, and the noise in the estimation of the centers of the pupil and corneal reflections. A detailed example of a system that uses the general theory to estimate the POG on a computer screen is presented. 相似文献
147.
Rosenthal A Horowitz M 《Journal of the Optical Society of America. A, Optics, image science, and vision》2006,23(1):57-68
In order to reconstruct the structure of a long-period grating, both the complex core-to-core transmission function and the complex core-to-cladding transmission function should be known. However, in practice, only the core-to-core transmission function of the grating can be measured. We demonstrate theoretically the reconstruction of long-period gratings from only the core-to-core transmission function. The reconstruction is performed by extracting the complex core-to-cladding transmission function of the grating from its core-to-core transmission function. Generally, the extraction is not unique; however, we show that by writing an additional grating in cascade to the interrogated grating, a unique reconstruction can be obtained. In weak long-period gratings, only the amplitude of the core-to-core transmission function is needed to reconstruct the grating. The results of our work can enable the experimental reconstruction of long-period gratings from their transmission function as well as the development of novel distributed sensors. 相似文献
148.
Moshe Dayan 《Journal of Superconductivity and Novel Magnetism》2013,26(3):575-587
Here, I extend my last work about the origin of the pseudogaps in underdoped cuprates (Dayan in arXiv:1011.3206 cond-mat, 2010) to include the mechanism of superconductivity. This is done by adapting the formalism of the double correlations in systems with nested Fermi surfaces to the semi one-dimensional system of strings of holes. It is proposed that magnetic interaction is crucial for the establishment of the pseudogap and the high temperature superconductivity. It is shown that superconductivity disturbs the completeness of the strings of holes, and creates fluctuations in them. This, in turn, reduces the magnetic interaction and the pseudogap order. 相似文献
149.
Moshe Shaked 《技术计量学》2013,55(4):457-466
Accelerated life testing for distributions with hazard rate functions of the form r(t) = Ag(t) + Bh(t) are considered. Let V 1, …, V k be stress levels larger than V 0—the stress level under normal conditions [V 0 > 0]—and let a(v) be a nondecreasing function on (0, ∞). We discuss a generalization of the common accelerated models (the power rule model and the Arrhenius model) by assuming that the hazard rate under the stress level V, is of the form (a(V t )) P (Ag(t) + Bh(t)). The maximum likelihood estimators of A, B and P for complete and censored samples are studied. The estimation procedure reduces to a solution of one equation with one unknown parameter. The estimation procedure under the assumption of aging is also described. The asymptotic variance-covariance matrix is given. 相似文献
150.