Investing in the Personality Vulnerability Research Program--Current Dividends and Future Growth: Rejoinder to Coyne, Thompson, and Whiffen (2004).

The authors do not see any benefit to J. C. Coyne. R. Thompson, and V. Whiffen's (2004) proposal to draw sharp boundaries between psychodynamic vulnerability theories, research on the onset of syndromal depression, and research with vulnerable, nondepressed populations. These domains have been and remain mutually relevant. Coyne et al. did not bring forward new evidence concerning the 6 issues addressed by D. C. Zuroff. M. Mongrain. and D. A. Santor (2004); consequently, the authors stand by their conclusions. According to Lakatos (as cited in B. Gholson & P. Barker. 1985), scientists justifiably continue to invest in research programs as long as the programs remain progressive. The personality vulnerability program is theoretically and empirically progressive and merits continued investment. Nevertheless, the field would benefit if Coyne et al. articulated a systematic contextualist research program to compete with the personality research program. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Measuring sheet resistance of CIGS solar cell's window layer by spatially resolved electroluminescence imaging

A spatially resolved electroluminescence (EL) imaging experiment is developed to measure the local sheet resistance of the window layer, directly on the completed CIGS cell. Our method can be applied to the EL imaging studies that are made in fundamental studies as well as in process inspection. The EL experiment consists in using solar cell as a light emitting device: a voltage is applied to the cell and its luminescence is detected. We develop an analytical and quantitative model to simulate the behavior of CIGS solar cells based on the spread sheet resistance effect in the window layer. We determine the repartition of the electric potential on the ZnO, for given cell's characteristics such as sheet resistance and contact geometries. Knowing the repartition of the potential, the EL intensity is measured and fitted against the model. The procedure allows the determination of the window layer sheet resistance.     

Polymer/layered silicate nanocomposites by combined intercalative polymerization and melt intercalation: a masterbatch process

Poly(ε-caprolactone) (PCL) and poly(vinyl chloride) (PVC) layered silicate nanocomposites were prepared by combination of intercalative polymerization and melt intercalation. In a first step, high clay content PCL nanocomposites were prepared by in situ polymerization of ε-caprolactone intercalated between selected organo-modified silicate layers. The polymerization was catalyzed with dibutyltin dimethoxide in the presence of montmorillonites, the surface of which were previously exchanged with (functionalized) long alkyl chains ammonium cations. Then, these highly filled PCL nanocomposites were added as masterbatches in commercial PCL and PVC by melt blending. The intercalation of PCL chains within the silicate layers by in situ polymerization proved to be very efficient, leading to the formation of intercalated and/or exfoliated structures depending on the organo-clay. These masterbatches were readily dispersed into the molten PCL and PVC matrices yielding intercalated/exfoliated layered silicate nanocomposites which could not be obtained by melt blending the matrix directly with the same organo-modified clays. The formation of nanocomposites was assessed both by X-ray diffraction and transmission electronic microscopy. Interestingly, this so-called ‘masterbatch’ two-step process allowed for preparing PCL nanocomposites even with non-modified natural clay, i.e. sodium montmorillonite, which showed a material stiffness much higher than the corresponding microcomposites recovered by direct melt intercalation. The thermal stability of PCL nanocomposites as a function of clay content was investigated by thermogravimetry (TGA).     

Long-term functional outcome following transient middle cerebral artery occlusion in the rat: Correlation between brain damage and behavioral impairment.

The assessment of both histological and functional long-term outcomes after cerebral ischemia is increasingly recommended for preclinical studies. Whereas correlations between behavioral impairments and primary ischemic lesion are documented, little is known about their relationships with remote nonischemic regions that undergo secondary degeneration, such as the thalamus. Anesthetized rats were subjected to mild (30 min) or severe (60 min) occlusion of the middle cerebral artery. Two months after ischemia, sensorimotor behavior was assessed according to the neurological score, limb-placing, adhesive-removal, and staircase tests; the final histological lesion was measured after this assessment. Cortical damage was correlated to all transient and long-lasting sensorimotor deficits, whereas striatal lesion was more consistently reflected by the forelimb-placing reflexes and adhesive-removal motor deficits. By contrast, the thalamic atrophy was not correlated to early neurological impairment, but rather to the late sensory deficit at the adhesive-removal test and to the skilled forepaw reaching alteration at the staircase test. This suggests that thalamus contributes, albeit moderately, to the ischemia-induced long-lasting sensorimotor deficits, some of which represent relevant targets for therapeutic interventions. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Caractéristiques associées à la coocurrence du trouble des conduites et de problèmes de consommation de psychotropes chez les gar?ons et les filles.

Although intervention for adolescents with concomitant conduct disorders and substance abuse must be adapted to the individual, familial and social characteristics of the adolescent, few studies have examined the characteristics specific to the concomitance of these problems. The objective of this study was to examine the differences between adolescents who present with one or both of these problems. The study sampled 486 teenagers (146 girls and 340 boys) divided into one of 4 groups on the basis of the presence or absence of conduct disorder and substance abuse. Results showed that girls with conduct disorder alone present problems as severe as those with concomitant conduct disorder and substance abuse but less severe than those with only substance abuse. For boys, those with the concomitant disorders appeared to have problems more servere than those with conduct disorders alone and less severe than those with substance abuse alone. These findings are discussed in terms of the need to tailor intervention to gender and presenting problem(s). (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

SPETA: Social pervasive e-Tourism advisor

Tourism is one of the major sources of income for many countries. Therefore, providing efficient, real-time service for tourists is a crucial competitive asset which needs to be enhanced using major technological advances. The current research has the objective of integrating technological innovation into an information system, in order to build a better user experience for the tourist. The principal strength of the approach is the fusion of context-aware pervasive systems, GIS systems, social networks and semantics. This paper presents the SPETA system, which uses knowledge of the user’s current location, preferences, as well as a history of past locations, in order to provide the type of recommender services that tourists expect from a real tour guide.     

Validation of the performance of a GMO multiplex screening assay based on microarray detection

A new screening method for the detection and identification of GMO, based on the use of multiplex PCR followed by microarray, has been developed and is presented. The technology is based on the identification of quite ubiquitous GMO genetic target elements first amplified by PCR, followed by direct hybridisation of the amplicons on a predefined microarray (DualChip^® GMO, Eppendorf, Germany). The validation was performed within the framework of a European project (Co-Extra, contract no 007158) and in collaboration with 12 laboratories specialised in GMO detection. The present study reports the strategy and the results of an ISO complying validation of the method carried out through an inter-laboratory study. Sets of blind samples were provided consisting of DNA reference materials covering all the elements detectable by specific probes present on the array. The GMO concentrations varied from 1% down to 0.045%. In addition, a mixture of two GMO events (0.1% RRS diluted in 100% TOPAS19/2) was incorporated in the study to test the robustness of the assay in extreme conditions. Data were processed according to ISO 5725 standard. The method was evaluated with predefined performance criteria with respect to the EC CRL method acceptance criteria. The overall method performance met the acceptance criteria; in particular, the results showed that the method is suitable for the detection of the different target elements at 0.1% concentration of GMO with a 95% accuracy rate. This collaborative trial showed that the method can be considered as fit for the purpose of screening with respect to its intra- and inter-laboratory accuracy. The results demonstrated the validity of combining multiplex PCR with array detection as provided by the DualChip^® GMO (Eppendorf, Germany) for the screening of GMO. The results showed that the technology is robust, practical and suitable as a screening tool.     

Inclusive Web Empirical Studies in Remote and In-Situ Settings: A User Evaluation of the RemoTest Platform

Web accessibility evaluation requires tests to be carried out with real users with disabilities performing real tasks or activities. To recruit an appropriate group of users and to observe their performance in the real world is difficult. For this reason we have developed RemoTest, a platform that assists researchers designing experiments, conducting remote and in-situ experimental sessions and analyzing the data gathered while the users are accessing the Web. Although this tool is oriented to experimenters, it is necessary to check whether the evaluation environments created by RemoTest are accessible or not to the users that participate in the tests. To this end, we conducted formal in-situ evaluations with 36 users with diverse characteristics. For this assessment, the participants were asked to install the platform, to fill in some automatically created questionnaires and to carry out several web navigation tasks. From the data gathered we analyzed the ease of the installation process, the accessibility of the automatically generated questionnaires, and user satisfaction. The results revealed the suitability of the platform for conducting inclusive experiments both in remote and in-situ contexts and provided guidelines on how the experiments should be set out.