Search for a protein kinase specific for treponin T

A specific to troponin T (as compared to f1 histone) proteinkinase is isolated using affinity chromatography on Sepharose 4B with covalently bound dephosphorylated troponin T. Homogeneous proteinkinase has a molecular weight of 175.000 and phosphorylates troponin T at a rate exceeding that of histone phosphorylation, while crude proteinkinase preparation has troponin T phosphorylation rate 15--20 times as low as that of histone phosphorylation. The enzyme isolated is capable of phosphorylating troponin T, but not troponin I, in the whole troponin complex.     

A preliminary report on the antiarrhythmic action of some newly synthesized glutarimide compounds

The effects of a new series of glutarimide compounds have been studied in acetylcholine induced auricular fibrillation in anaesthetized cats and epinephrine induced ventricular arrhythmmias in conscious pigeons. Some of the compounds showed varying degree of protective action against experimental arrhythmias. However these compounds were found to be less potent than quinidine. The mechanism of antiarrhythmic action has been discussed.     

CT abnormalities of the pituitary in hyperprolactinaemic women with normal or equivocal sellae radiologically

Sixteen young women with hyperprolactinaemia and normal or equivocal sella in radiographs underwent computed tomography using a Siemens Somatom II. In all but one case an abnormality was found. The sella was full in seven and partially empty in nine. A tumour was visible in six of the full and in four of the partially empty sellae. All but one of the 10 tumours was unilateral, and in seven the pituitary stalk was deviated away from the tumour. After administration of intravenous contrast (Urografin) four tumours showed diffuse enhancement, four ring enhancement, and two enhanced less than adjacent normal pituitary tissue. Two of the tumours have been subsequently shown histologically to be prolactinomas. Prolactin response to thyrotrophin-releasing hormone predicted a tumour in seven out of eight with visible tumours but also in three out of four without visible tumours; using metoclopramide, a tumour was predicted in six out of seven with tumours, but again in three out of four without visible tumours. Such results question the value of dynamic tests for the discrimination of tumours. We conclude that practically all women with sustained hyperprolactinaemia and a normal or equivocal sella radiologically have pituitary disease.     

酷睿2代T5系列处理器网友疑难解答

网友提问酷睿2T5X X X的技术参数?T5600:2M B二级缓存,1.83G H z主频,667M H z前端总线,支持虚拟化技术;T5500:2M B二级缓存,1.66G H z主频,667M H z前端总线,不支持虚拟化技术;另外,最新推出的T5200是降频“缩水”版本,2M B二级缓存,1.6G H z主频,533M H z前端总线,不支持虚拟