Binary rewriting and call interception for efficient runtime protection against buffer overflows

Buffer overflow vulnerabilities are one of the most commonly and widely exploited security vulnerabilities in programs. Most existing solutions for avoiding buffer overflows are either inadequate, inefficient or incompatible with existing code. In this paper, we present a novel approach for transparent and efficient runtime protection against buffer overflows. The approach is implemented by two tools: Type Information Extractor and Depositor (TIED) and LibsafePlus. TIED is first used on a binary executable or shared library file to extract type information from the debugging information inserted in the file by the compiler and reinsert it in the file as a data structure available at runtime. LibsafePlus is a shared library that is preloaded when the program is run. LibsafePlus intercepts unsafe C library calls such as strcpy and uses the type information made available by TIED at runtime to determine whether it would be ‘safe’ to carry out the operation. With our simple design we are able to protect most applications with a performance overhead of less than 10%. Copyright © 2006 John Wiley & Sons, Ltd.     

Fatigue characteristics of pulsed MIG-welded Al-Zn-Mg alloy

Pulse-current MIG welding of Al-Zn-Mg alloy was carried out using an extruded section of base material and Al-Mg (5183) filler wire. During welding the pulse parameters such as the mean current and pulse frequency were varied and their effect on the geometry and porosity content of weld deposit as well as the fatigue life of the weldment was studied. The pulse parameters were found to affect significantly the geometry and porosity content of weld deposit and consequently the fatigue life of the weldment. For a comparative study, weldments were also prepared by using conventional continuous current MIG-welding process, where welding currents equivalent to the mean currents of pulsed process were used. The fatigue life of the weldment was correlated with the geometry and porosity content of weld deposit.     

Pulsed underwater corona discharges as a source of strong oxidants: *OH and H2O2.

Because of undesirable side effects of chemical methods pulsed underwater corona discharges are emerging as a potential future advanced oxidation process (AOP) for water disinfection. In pulsed corona discharges a discharge channel is created, which contains a non-thermal plasma with a low degree of ionisation and low electron densities, but with electron energies of up to 10 eV. It has been demonstrated that electrons with this energy can dissociate water and oxygen molecules and produce various reactive radicals (*OH, H*, O*, HO2*), molecular species (H2O2, H2, O2), ultraviolet radiation and shock waves. It is supposed that the combination of all effects leads to a very efficient killing of microorganisms. To understand this in detail and to improve the efficiency of the overall system there is the need to develop suitable diagnostic methods for the quantitative determination of the various oxidants produced during the discharge. In this paper we present preliminary experimental results obtained with different chemical probes for *OH radicals, and H2O2 produced by pulsed corona discharges.     

Protective effect of Picroliv from Picrorhiza kurroa against Leishmania donovani infections in Mesocricetus auratus

The prevalent drugs for treatment of kala azar viz. sodium stibogluconate (SSG) and pentamidine cause severe toxic side effects and acute immunosuppression in the treated individuals. Picroliv, a standardized mixture of iridoid glycosides, prepared from the alcoholic extract of the root and rhizome of Picrorhiza kurroa has shown strong hepatoprotective activity against several models of hepatotoxicity. Therefore, the present study was undertaken with an objective to study the effects of Picroliv (12.5 mg/kg x 7 days oral) alone and in combination with SSG on parasitemia, lipid peroxidation and hepatic marker enzymes of golden hamsters during Leishmania donovani infection. The results indicated a marked hepatoprotective effect of Picroliv in terms of biochemical markers, and a significant antileishmanial activity implying that it can be utilized as an adjunct to chemotherapy or in combination therapy of kala azar along with sodium stibogluconate, thus enhancing the efficacy of antileishmanials.     

Regulation of interrenal secretion in the axolotl, Ambystoma mexicanum

The regulation of corticosteroid secretion of the adrenal cortex (interrenal tissue) of axolotl (Ambystoma mexicanum) was studied using in vitro preparations of kidney containing interrenal tissue. Normally, 0.3-0.65 ng/5 min corticosterone and 0.15-0.3 ng/5 min aldosterone were released from the tissue. Regulatory peptides were effective in the following range: ACTH = arginine vasotocin > urotensin II > angiotensin II. They stimulate an elevation of corticosterone (plus 0.2-1 ng/5 min) and of aldosterone (plus 0.05-0.15 ng/5 min). The three primary effector systems leading to second messengers, adenylate cyclase (forming cAMP), phospholipase C (forming InsP3 + DAG), and phospholipase A2 (liberating arachidonic acid) are involved in stimulation of biosynthesis. It can be suggested that the second messengers stimulate the biosynthesis at the level of the steps between pregnenolone and corticosterone ('3 beta-hydroxysteroid-dehydrogenase etc.), because the release of corticosterone is more stimulated than aldosterone. This is different than the regulation of anuran interrenal tissue. Ca++ ions are involved in corticosterone secretion. Verapamil inhibits immediately the secretion of corticosteroids and elevation of external Ca++ stimulates the release. It is suggested that Ca++ mediates the secretion process itself. Metamorphosis does not change the response of the interrenal gland compared with the neotenic animal.     

Increased incidence of spina bifida occulta in fluorosis prone areas

Spina bifida, a congenital deformity of the posterior wall of vertebrae of the spine, is a midline defect of skin, vertebral arches and neural tube, usually in the lumbosacral region. Its incidence is reported to be 0.2 to 0.4 per 1000 live births. Various hypotheses have been put forward as etiological factors for spina bifida including consumption of potato affected by blight and hardness of drinking water but these have not been proven. Two groups of 50 randomly chosen children were established. The study group consisted of children aged 5 to 12 years, weighing 15 to 30 kg, consuming fluoride rich drinking water (4.5 and 8.5 ppm fluoride; WHO permissible limit is 1.5 ppm fluoride), and manifesting either clinical, dental and/or skeletal fluorosis. The control group consisted of age and weight-matched children, consuming less than or equal to 1.5 ppm fluoride in drinking water and not showing any evidence of fluoride toxicity. These children were evaluated for antenatal history, general clinical examination (especially for dimples, tufts of hair, haemangioma on skin throughout the length of spine), other congenital abnormalities, evidence of fluoride toxicity, biochemical estimation for fluoride levels in blood and serum and by skiagrams of the spine to examine for the presence of spina bifida occulta. A total of 22 (44%) of the 50 children in group A, the study group, and 6 (12%) of the 50 children in group B, the control group, revealed spina bifida occulta in the lumbosacral region.(ABSTRACT TRUNCATED AT 250 WORDS)     

Value of image-guided needle aspiration cytology in the assessment of thoracolumbar and sacrococcygeal masses

We have used a primary cloning assay to determine the frequency of 6-thioguanine (TG)-resistant tubular epithelial cells in kidney tissue from 72 human donors ranging in age from 2 to 94 years. The frequency of TG-resistant mutants ranged from approximately 5 x 10(-5) for donors in the first decade of life to approximately 2.5 x 10(-4) for donors in the eighth and later decades of life. Two different statistical analyses indicated that this increase in mutant frequency is exponential with age. We also observed a 2-fold higher TG-resistant mutant frequency in nephrectomy kidneys containing a coincident renal carcinoma. DNA sequence analyses revealed HPRT gene mutations in each of 14 TG-resistant mutants from seven unrelated donors. Thirteen of these 14 mutants resulted from independent mutational events. These results suggest that somatic mutations are common in renal--and perhaps in other human--epithelia, and thus could play an important role in the genesis of age-associated disease.     

Selection of optimized features for fusion of palm print and finger knuckle‐based person authentication

The impact of digital technology in biometrics is much more efficient at interpreting data than humans, which results in completely replacement of manual identification procedures in forensic science. Because the single modality‐based biometric frameworks limit performance in terms of accuracy and anti‐spoofing capabilities due to the presence of low quality data, therefore, information fusion of more than one biometric characteristic in pursuit of high recognition results can be beneficial. In this article, we present a multimodal biometric system based on information fusion of palm print and finger knuckle traits, which are least associated to any criminal investigation as evidence yet. The proposed multimodal biometric system might be useful to identify the suspects in case of physical beating or kidnapping and establish supportive scientific evidences, when no fingerprint or face information is present in photographs. The first step in our work is data preprocessing, in which region of interest of palm and finger knuckle images have been extracted. To minimize nonuniform illumination effects, we first normalize the detected circular palm or finger knuckle and then apply line ordinal pattern (LOP)‐based encoding scheme for texture enrichment. The nondecimated quaternion wavelet provides denser feature representation at multiple scales and orientations when extracted over proposed LOP encoding and increases the discrimination power of line and ridge features. To best of our knowledge, this first attempt is a combination of backtracking search algorithm and 2D²LDA has been employed to select the dominant palm and knuckle features for classification. The classifiers output for two modalities are combined at unsupervised rank level fusion rule through Borda count method, which shows an increase in performance in terms of recognition and verification, that is, 100% (correct recognition rate), 0.26% (equal error rate), 3.52 (discriminative index), and 1,262 m (speed).     

Artificial intelligence capability: Conceptualization,measurement calibration,and empirical study on its impact on organizational creativity and firm performance

Artificial intelligence (AI) has been heralded by many as the next source of business value. Grounded on the resource-based theory of the firm and on recent work on AI at the organizational context, this study (1) identifies the AI-specific resources that jointly create an AI capability and provides a definition, (2) develops an instrument to capture the AI capability of the firms, and (3) examines the relationship between an AI capability and organizational creativity and performance. Findings empirically support the suggested theoretical framework and corresponding instrument and provide evidence that an AI capability results in increased organizational creativity and performance.