Small-active-area germanium avalanche photodiode for single-mode fibre at 1.3 ?m wavelength

A germanium avalanche photodiode of 30 ?m active area diameter has been fabricated and tested. The multiplied dark current is as low as 5 nA at room temperature. A module using this diode and a spherical lens has been assembled and coupled with a single-mode fibre of core diameter 10 ?m. The quantum efficiency of the module is 90% at 1.3 ?m. The sensitivity is measured at 45 Mbit/s and at 1.3 ?m. Minimum detectable powers obtained for 10?11 error rate are ?51.9 dBm and ?50.7 dBm at 25°C and 50°C, respectively.     

An Integrated Controlled-Current PWM Rectifier Chopper Link for Sliding Mode Position Control

Position controllers must handle kinetic energy exchanges during acceleration and deceleration of large inertias. Temporary buffer storage in capacitors is expensive. The system that can manage the power exchange with ease is the integrated controlled-current pulsewidth-modulated (PWM) rectifier/controlled-current PWM chopper link. Bidirectional power is accomplished by bidirectional current flow in the dc link for both modulators. The three-phase currents in the rectifier side are near sinusoidal in waveform at unity power factor. The performance of the system as a position controller in an environment of the sliding mode strategy is studied. The sliding mode strategy offers robust characteristics to the controller.     

Simultaneous manifestation of squamous cell carcinoma in identical twins with epidermolysis bullosa

We report a case of identical twins with recessive dystrophic epidermolysis bullosa, who developed squamous cell carcinoma in the hand at the latter half of their third decade. To our knowledge, this is the first case of manifestation of squamous cell carcinoma in identical twins and may contribute to the understanding of oncogenesis in such patients.     

Dis3, implicated in mitotic control, binds directly to Ran and enhances the GEF activity of RCC1

Using the two-hybrid method, we isolated a Saccharomyces cerevisiae cDNA encoding a protein homologous to Schizosaccharomyces pombe protein Dis3sp, using as bait, human GTPase Ran. The DIS3 gene is essential for viability and complements S.pombe mutant dis3-54 which is defective in mitosis. Although Dis3sc has no homology to RanBP1, it bound directly to Ran and the S.cerevisiae Ran homologue Cnr1, but not to the S.cerevisiae RCC1 homologue Srm1. Upon binding to Ran with a 1:1 molar ratio, Dis3sc enhanced a nucleotide-releasing activity of RCC1 on Ran. In the presence of Dis3sc, the K(m) of RCC1 on Ran decreased by half, while the kcat was unchanged. In vivo, Dis3sp was present as oligomers of M(r) 670-200 kDa as previously reported, and the 200 kDa oligomer of Dis3sp was found to include Spi1 and Pim1, the S.pombe homologues of Ran and RCC1, respectively. Although the biological function of the heterotrimeric oligomer consisting of Dis3, Spi1 and Pim1 is unknown, our results indicate that Dis3 is a component of the RCC1-Ran pathway.     

InGaAsP double-channel- planar-buried-heterostructure laser diode (DC-PBH LD) with effective current confinement

A new high-performance 1.3-μm InGaAsP semiconductor laser is described, in which effective current confinement into the active region has been realized. A p-n-p-n current blocking structure is made by liquid-phase epitaxy (LPE) on both sides of the active-stripe mesa which is defined by a pair of channels in the double-heterostructure wafer. The double-channel-planar-buried-heterostructure laser diodes (DC-PBH LD's) exhibit high-laser performances, such as a high differential quantum efficiency of 78-percent maximum, which results in high electrical to optical power conversion efficiency 43 percent, and high light output power of over 50 mW, as a result of the improvement in the current blocking structure. The threshold current temperature sensitivity is found experimentally to be reduced remarkably by increasing the doping concentration in the p-cladding layer. Characteristic temperature as high as 100 K has been obtained. CW operation is possible up to 130°C.     

Development of µGC (micro gas chromatography) with high performance micromachined chip column

A micro gas chromatography (µGC) instrument applying a high performance chip column fabricated on a silicon wafer was developed. Experimental results of the chip column and protyping of a µGC instrument are described. Approximately 35 000 theoretical plates were generated with the chip column coated liquid phase (5% phenyl-/95% dimethyl-polysiloxane). The theoretical plates of the chip column were close to those of the capillary column. Experimental minimum height equivalent to a theoretical plate (HETP, H_min) of the chip column was 1.2 times higher than the calculated H_min. A prototype µGC applying the chip column was developed. The µGC generated approximately 35 000 theoretical plates, similar to the theoretical plates obtained by a commercial GC instrument. Copyright © 2009 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.     

日本国保桥本市民医院工程简介

本文对日本国保桥本市民医院工程做一概述。     

Plasma CVD of (BaSr)TiO3 Dielectrics for Gigabit DRAM Capacitors

Electron cyclotron resonance (ECR) plasma chemical vapor deposition (CVD) of (BaSr)TiO₃ dielectrics is reviewed. The oxygen plasma lowered the crystallization temperature and carbon contamination. (BaSr)TiO₃ CVD process was developed under conditions of relatively low deposition rate of 1.1 nm/min and a relatively low deposition temperature of 550°C. Utilizing this process, we developed a gigabit dynamic random access memory (DRAM) capacitor technology involving the preparation of a thin (BaSr)TiO₃ capacitor dielectric over a RuO₂/Ru storage node contacting a TiN/TiSi _X /poly-Si plug. The ECR plasma CVD enabled uniform deposition of gigabit-DRAM-quality (BaSr)TiO₃ films on the electrode sidewalls. The storage node contact improved in endurance against oxidation, by fabricating the buried-in TiN/TiSi _X plug (TiN-capped plug) under the RuO₂/Ru storage node. (BaSr)TiO₃ films with a small equivalent SiO₂ thickness of 0.38 nm and a leakage current density of 8.5×10^–7 A/cm² at an applied voltage of 1.0 V, were obtained without any further annealing process. An equivalent SiO₂ thickness of 0.40 nm on the RuO₂ sidewall was also achieved. It is concluded that this technology has reached the requirements for gigabit DRAM capacitors.     

Acceptor recognition of kojibiose phosphorylase from Thermoanaerobacter brockii: syntheses of glycosyl glycerol and myo-inositol

The glucosyl transfer reaction of kojibiose phosphorylase (KP; EC 2.4.1.230) was examined using glycerol or myo-inositol as an acceptor. In the case of glycerol, KP produced two main transfer products: saccharides A and B. The structure of saccharide A was O-alpha-D-glucopyranosyl-(1-->1)-glycerol and that of saccharide B was O-alpha-D-glucopyranosyl-(1-->2)-O-alpha-D-glucopyranosyl-(1-->1)-glycerol. These results show that KP transferred a glucose residue to the hydroxyl group at position 1 of glycerol. On the other hand, when myo-inositol was used as an acceptor, KP produced four transfer products: saccharides 1-4. The structures of saccharides 1 and 2 were O-alpha-D-glucopyranosyl-(1-->1)- and O-alpha-D-glucopyranosyl-(1-->5)-myo-inositol, respectively; those of saccharides 3 and 4 were O-alpha-D-glucopyranosyl-(1-->2)-O-alpha-D-glucopyranosyl-(1-->1)- and O-alpha-D-glucopyranosyl-(1-->2)-O-alpha-D-glucopyranosyl-(1-->5)-myo-inositol, respectively. KP transferred a glucose residue to the hydroxyl group at position 1 or 5 of myo-inositol. On the basis of the structures of their glucosyl transfer products, glycerol and myo-inositol were found to have a common structure with three hydroxyl groups corresponding to the hydroxyl group of the glucose molecule at positions 2, 3 and 4. The conformation of these three hydroxyl groups in the structure is equatorial. This structure is the substrate recognition site of KP. It has been suggested that KP strictly recognizes the structures of glycerol and myo-inositol, and catalyzes the transfer reaction of a glucose residue to the hydroxyl group at position 1 in glycerol, and at position 1 or 5 in myo-inositol, corresponding to position 2 in glucose.